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Interdisciplinary researchers receive $2M to develop next-generation 3D ultrasound imaging device

Interdisciplinary researchers at the Beckman Institute have received a four-year, $2M award from the National Institutes of Health to develop a device that can instantly enable real-time 3D ultrasound imaging. The device, named FASTER, is designed to improve high-quality medical imaging accessibility in diverse communities.

Towards stable, sustained Raman imaging of large samples at the nanoscale

A research team from Japan has developed a stable TERS system that enables characterization of defect analysis in large-sized WS2 layers at high pixel resolution. The team successfully imaged nanoscale defects over a period of 6 hours in a micrometer-sized WS2 film without significant signal loss.

SourceInstitute of Post-LED Photonics, Tokushima University·JournalScience Advances·TypeExperimental study·DateJul 15, 2022

Artificial intelligence technology accelerates super-resolution localization photoacoustic imaging of blood vessels

A new AI-based localization technique enhances photoacoustic imaging speed and spatial resolution, reducing laser exposure and imaging time. The technology offers a solution for preclinical and clinical applications requiring fast and fine spatial resolution.

Researchers demonstrate label-free super-resolution microscopy

A new measurement and imaging approach resolves nanostructures smaller than the diffraction limit without dyes or labels, using polarization and angle-resolved images of transmitted light. The method measures particle size and position with high accuracy, closing the gap between conventional microscopes and super-resolution techniques.

SourceOptica·JournalOptica·DateApr 21, 2022

OLID-SDOM reveals fluorescence anisotropy of subcellular structures in live cells

Researchers create OLID-SDOM to map weak fluorescence anisotropy in live cells, achieving high-resolution images of subcellular structures at 100 frames per second. The method overcomes limitations of previous techniques, enabling the study of molecular arrangement and rotation in biological systems.

AI and ghost imaging boosts super resolution imaging

A team of scientists developed an AI-driven super-resolution technique called Ghost Imaging using Deep neural network Constraint (GIDC) to overcome the diffraction limit in long-distance imaging. GIDC uses single-pixel measurements and a physics-enhanced deep neural network to restore high-quality images.

OLID-SDOM reveals fluorescence anisotropy of subcellular structures in live cells

A new method termed Optical Lock-in Detection Super-resolution Dipole Orientation Mapping (OLID-SDOM) is developed for weak fluorescence anisotropy mapping in live cells. This approach achieves high spatial resolution and speed, allowing for the study of subcellular structures with unprecedented precision.

Correlative chemical imaging directly in neurons

Researchers use super-resolution infrared imaging combined with X-ray fluorescence nano-imaging to study amyloid toxicity on a subcellular level. They found that the distribution of trace elements in neurons is related to molecular mechanisms of Alzheimer's disease, offering new insights into preventing neuronal damage.

Nanoimprinted hyperlens array: Paving the way for practical super-resolution imaging

Researchers at Pohang University of Science & Technology have developed a scalable fabrication process for large-scale hyperlens devices using nanoimprint lithography. This breakthrough enables the creation of sub-diffraction features down to 160 nm, paving the way for practical super-resolution imaging in various fields.