Articles tagged with Neurospheres
The study proposes a model to understand the complications caused by zika virus infection during pregnancy. The researchers found that zika virus alters protein expression in neural cells, affecting energy production and RNA metabolism, which can lead to defective myelination and microcephaly.
Researchers have found that Zika virus alters the expression of hundreds of genes responsible for guiding brain cell formation, leading to microcephaly. The study reveals new therapeutic targets by analyzing molecular interactions in infected brain cells.
Research by Brazilian scientists at D'Or Institute for Research and Education reveals Zika virus infection in human neural stem cells causes cell death, malformations, and reduced growth in neurospheres and brain organoids. The study highlights the etiological nature of microcephaly cases in Brazil.
A study by Hong Wu and colleagues found that knocking out the gene Pten in mice hyper-activated a signaling pathway regulating cell proliferation and death in the brain. This led to an increase in brain size and cell number, suggesting PTEN regulates neural stem cell growth.