Researchers at the University of Illinois used single calcite crystals with varying surface roughness to simplify the physics of fault movement. The study found that friction can increase or decrease with sliding velocity depending on mineral types and environment, providing a fundamental understanding of rate-and-state equations.
Researchers have developed novel 3D atomic force microscopy (AFM) probes with improved designs, materials, and production processes. The new probes enable high-resolution, high-speed AFM imaging under air and liquid environments, opening doors for advanced applications in fields like biomedical sciences.
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Scientists from Martin-Luther-University Halle-Wittenberg discovered that precisely applied mechanical pressure can improve the electronic properties of polyvinylidene fluoride (PVDF) films. The team used atomic force microscopy to control and reorient electrical charges in the material, enabling stable nano-scale structures with high ...
A research team from Japan has developed a stable TERS system that enables characterization of defect analysis in large-sized WS2 layers at high pixel resolution. The team successfully imaged nanoscale defects over a period of 6 hours in a micrometer-sized WS2 film without significant signal loss.
Researchers at Samsung have developed a novel approach to inspect critical dimensions of semiconductor devices, improving speed and resolution. The new 'line-scan hyperspectral imaging' (LHSI) technique offers faster measurements with high spatial resolution, outperforming existing methods.
A study by researchers at Pusan National University has investigated the relationship between surface structures and nanoscale friction in multi-layered CVD graphene. They found that only the top-most layer of graphene was twisted with respect to the rest, affecting layer-dependent nanoscale friction.
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The study found that trace solvent additives enhance ordering and crystallization of polymer microstructure, increasing power conversion and photocurrent density by up to 3 times. This improvement helps form a network that efficiently transports photogenerated charges, increasing local photocurrents.
University of Rochester researchers adapt excited state lifetime thermometry to extract temperatures of nanoscale materials from light emitted by nitrogen vacancy centers in single nanodiamonds. The technique allows for precise measurement of temperature changes on fast time scales and is safe for imaging sensitive nanoscale materials ...
Researchers successfully carried out the first on-surface intramolecular Diels-Alder reaction, generating valuable intermediate molecules. This breakthrough allows for a better understanding of the transformation's mechanisms and potential design of new reactions.
Researchers at Japan Advanced Institute of Science and Technology have developed a novel method to fabricate diamond probes with controlled shape and higher sensitivity. These probes enabled the imaging of periodic magnetic domain structures in ferromagnets, showing promise for quantum applications.
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A team of researchers has developed a new technique to embed single atoms in silicon wafers, mirroring methods used to build conventional devices. The technique creates large-scale patterns of controlled atoms that can be manipulated and read out, enabling the construction of large-scale quantum devices.
Kanazawa University scientists design a zero-latency amplitude detector for high-speed atomic force microscopy, significantly improving temporal resolution. The new detector enables faster recording of biological processes with higher video frame rates and reduced invasiveness.
Scientists confirm existence of sigma-hole, a phenomenon previously predicted but never directly observed. This breakthrough enables understanding of interactions between individual atoms or molecules, facilitating refinement of material and structural properties.
Researchers have recorded the sharpest images of living bacteria, revealing a complex architecture that makes them harder to kill by antibiotics. The study found that bacteria with protective outer layers may have stronger and weaker spots on their surface.
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A research team led by Associate Professor Akira Kakugo of Hokkaido University has provided direct evidence that microtubules function as mechanosensors, slowing down kinesin movement when bent. This phenomenon is attributed to enhanced interaction energy between kinesin and deformed microtubule structural units.
Using advanced microscopy techniques, researchers recorded the breaking of a single chemical bond between a carbon atom and an iron atom on different molecules. The team measured the mechanical forces applied at the moment of breakage, revealing insights into the nature of these bonds and their implications for catalysis.
Scientists at Osaka University successfully mapped the three-dimensional forces acting on quantum dots with unprecedented subnanometer resolution, opening up new avenues for nanotechnology and optical manipulation. This breakthrough could lead to advances in photocatalysts and optical tweezers.
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Scientists at Weill Cornell Medicine developed a computational technique that greatly increases the resolution of atomic force microscopy, revealing atomic-level details on proteins and biological structures. The new method allows researchers to study biological molecules under physiologically relevant conditions, providing high-resolu...
Researchers developed a machine learning technique to speed up microscopic cell analysis, reducing processing time from months to just seconds. The new approach uses neural networks to create detailed maps of cell composition without disrupting the cells, enabling rapid label-free biochemical composition mapping.
Researchers developed a scanning quantum sensing microscope that maps local electric fields with a spatial resolution of ~10 nm and sensitivity close to an elementary charge. The technique allows for reversible control of single NV's charge states, enabling the purification of NV's electrostatic environment.
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Researchers at Vienna University of Technology have developed a new microscopy technique that allows for the measurement of atomic acidity on surfaces. This breakthrough enables analysis of catalysts on an atomic scale, which is crucial for improving chemical reactions.
Researchers at Kanazawa University created a new AFM approach to increase frame rates up to 30 fps, reducing sample disturbance and improving imaging capabilities.
Researchers at TU Wien have discovered a two-phase material with surprising electro-mechanical properties that change dramatically above a certain temperature. The team found that the crystals responsible for these properties remain electroactive, but the macroscopic behavior disappears due to a loss of contact between crystal grains.
A team led by Alexander Eichler has demonstrated the first scanning force microscope with a vibrating substrate, pushing sensitivity to its fundamental limit. The approach uses a perforated membrane as the 'table' and features an optical interferometer for sensitive measurement.
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Researchers use high-speed atomic force microscopy to visualize the structural dynamics and factor pooling of ribosome stalk proteins, shedding light on the translational GTPase factor mechanism. The study reveals two conformations of the stalk protein and provides evidence for a potential role in further stages of protein synthesis.
The study uses high-speed atomic force microscopy to image several intrinsically disordered proteins (IDPs) and identify parameters defining protein shapes and sizes. The technique reveals globules that appear and disappear, as well as transformations between fully unstructured and loosely folded conformations.
The BioAFMviewer software allows for the computational emulation of AFM scanning on any biomolecular structure, generating simulated graphics and movies. This facilitates the comparison of high-resolution structural data with AFM results, aiding in the analysis and interpretation of experimental outcomes.
Researchers at Binghamton University have won NSF funding for a new method of producing microscopic circuits. They plan to use carbon nanotubes to etch circuit patterns onto materials, potentially creating less expensive and more efficient production methods.
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Researchers at ORNL developed a quantum microscope that measures signals with sensitivity better than classical limits, revealing fine details hidden by noise in microscopy signals. The approach uses squeezed light to reduce noise and achieve higher signal-to-noise ratios.
Researchers at Kanazawa University developed a method to overcome constraints in high-sensitivity atomic force microscopy for photosensitive samples. By driving cantilevers with megahertz frequencies, they achieved stable control and imaging of surface topography and composition.
Studies of alpha-synuclein protein aggregates found variations in elongation rates and fibril structures, depending on cross-seeding and pH levels. High-speed atomic force microscopy enabled visualization of growth over time, shedding light on amyloid-related diseases.
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Researchers have developed a technique to control and visualize cell function expression at a high level, enabling minimally invasive surgery to living cells. This innovation aims to solve the mystery of life by manipulating cellular functions and visualizing biomolecules.
A Japanese research group led by Professor Shiki Yagai has successfully created polycatenanes, self-assembled molecule rings that can be observed under a microscope. By using atomic force microscopy, they confirmed the structure of poly[22]catenane made up of as many as 22 connected rings, reaching up to 500 nm in length.
Scientists study FG-NUPs in normal and colorectal cancer cells, finding altered conformational dynamics in cancer cells. The structure of the central plug is smaller, hindering filamentous features in cancer cells.
Developing new techniques to improve atomic force microscopy has reduced the noise associated with the technique. By utilizing a piezo component to maintain zero deflection, researchers can record IR signals with improved precision and image smaller sample volumes, like cell membranes.
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A new microscopy technique called Pulsed Force Kelvin Probe Force Microscopy (PF-KPFM) has been developed, allowing for less than 10 nanometer measurements of work function and surface potential in a single-pass AFM scan. This breakthrough enables the characterization of the electrical properties of nanomaterials at the nanoscale.
Researchers at TU Wien develop a method to study metal oxide surfaces using a single oxygen atom attached to an atomic force microscope tip, allowing for gentle examination of surface structures without altering the atoms. The technique reveals different ways oxygen molecules attach to titanium atoms on the surface.
Researchers visualized solid electrolyte interphase formation on battery-grade materials using in situ atomic force microscopy. They found SEI was thicker and stronger than on HOPG, providing new insights into battery interface structure and evolution.
A new visualization method using atomic force microscopy is developed to determine the distribution of components in battery electrodes, providing insights into optimal composite electrode conditions. The method has potential to improve performance and safety of all-solid-state lithium-ion batteries.
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Researchers create a novel method using magnetic tweezers to study the mechanical forces that activate proteins like VWF, which initiates blood clots. The technique reveals the unfolding of VWF dimers under low forces, shedding light on the first step in blood coagulation.
Researchers used X-ray imaging and nanoscale techniques to analyze the chemical processes involved in aging oil paints. The study found that metal soaps can cause deterioration in artworks, particularly those composed of oil paints. The findings have implications for art conservation and potential solutions to prevent further damage.
A multinational team successfully alters oxygen atoms' charge states and achieves reversible conversion to molecular oxygen using Kelvin probe force spectroscopy. The researchers found that controlled bonding between adjacent oxygen atoms can be induced remotely via surface polarons.
Engineers developed a novel scanning quantum dot microscopy method that enables the accurate measurement of electrical potentials at molecular resolution. This breakthrough allows for high-resolution images of potential fields, previously unattainable, and opens up possibilities for creating nanostructures via 3D printing.
Scorpion venom contains compounds that bind to K+ channels, inhibiting their function. High-speed atomic force microscopy revealed the association and dissociation dynamics of a peptide, AgTx2, with the K+ channel KcsA. The study found that AgTx2 binding is facilitated by an induced-fit mechanism, accelerating binding by 400-fold.
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Researchers at Oak Ridge National Laboratory have developed an online tool to evaluate the moisture durability of a building's envelope, enabling better-informed decisions for energy efficiency. Additionally, the lab has pioneered a new technique using pressure to manipulate magnetism in thin film materials used in electronic devices.
Researchers from Forschungszentrum Jülich developed a new scanning quantum dot microscopy method that can measure electric potentials of individual atoms and molecules. This allows for the characterization of biomolecules like DNA and opens up new opportunities for chip manufacture.
A team of scientists at Shinshu University used a newly customized tool to study hydrogel microspheres, observing structural differences that were previously unexplained. The study reveals that the method of production greatly affects the structure and behavior of thermoresponsive microgels.
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The study found that acidic environments make the HA0 molecule flatter and more circular, inducing conformational changes. The researchers used high-speed atomic force microscopy to visualize the structure of HA0 in real-time, paving the way for developing therapeutic approaches against influenza A viruses.
A new technique using micropipette force sensors measures the tiny forces exerted by living cells and microorganisms with high precision. The method allows for testing the reaction of cells to environmental factors and has potential applications in biomedicine, such as identifying drugs for infectious diseases.
Researchers have discovered that atomic force microscopes can be used to map the interior of materials, revealing patterns and properties previously unknown at the surface. This new technique has the potential to improve the design of computer chips and reduce energy consumption.
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Researchers from Empa successfully synthesized chain-shaped molecules between two microscopically small gold tips. The properties of the resulting molecule can be monitored in real time during synthesis, enabling the creation of electrically conductive molecules with atomic precision.
A team of researchers has discovered a 'blind spot' in atomic force microscopy that can lead to incorrect results due to the use of certain force laws. However, they have also developed a new mathematical method to identify and avoid this issue, safeguarding atomic force measurements from inaccurate results.
A team at University of Washington demonstrates an innovative approach to bridge AFM and big data, offering better spatial resolution and accuracy. By using sequential excitation strategy, they deduce physical insight from PCA data and speed up analysis by orders of magnitude.
University of Missouri researchers have developed a new microscope that allows them to observe individual proteins in an unfrozen sample. This breakthrough enables scientists to predict how cells will behave when new components are introduced, which could lead to the creation of more effective drugs with fewer side effects.
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A team of scientists has obtained direct images of dissolved organic carbon molecules from the ocean using atomic force microscopy. The visualization provides clues about their persistence in the marine environment and sheds light on the cycling of carbon in oceans, helping better understand the overall health of marine environments.
Researchers at EPFL have invented a new method to examine protein assembly mechanisms in real time using atomic force microscopy. The technique, which uses pulsed laser light, allows for the observation of dynamic processes that were previously impossible to study.
A team of physicists has successfully imaged individual impurity atoms in graphene ribbons using atomic force microscopy. The technique allowed them to identify boron and nitrogen atoms, expanding graphene's properties for applications like transistors and circuits.
Physicists and chemists at the University of Münster have developed a microscopic method to image organic molecules with exceptional resolution. The technique uses an atomically defined probe tip that greatly increases imaging resolution by reducing undesired interaction between atoms.
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The new microscope developed by SFU researchers allows for the study of molecular interactions under high forces and fast spinning speeds, revealing new insights into collagen stability. This breakthrough has significant implications for developing better treatments to prevent collagen degradation.
Researchers at the University of Alberta have developed a new way to produce high-density DC current, vastly improving over existing triboelectric nanogenerators. The discovery enables continuous flow of electricity from nanoscale movement and vibration, opening up potential applications in sensors, wearable devices, and more.