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New $1.25 million research project will map materials at the nanoscale

A University of Central Florida researcher is leading a $1.25 million project to map and manipulate materials at the nanoscale. The research aims to unlock new capabilities of materials at the nanoscale, potentially leading to new catalysts and compounds applicable in quantum science, renewable energy, life sciences and sustainability.

Chemists uncover cracks in the amour of cellulose nanocrystals

Researchers at Kanazawa University and their international collaborators used 3D-AFM and molecular dynamics simulations to study the surface chemistry and structure of individual cellulose nanocrystal particles. The findings reveal new details on chain arrangements, structural defects, and water molecule arrangement near the CNC surface.

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Tip tricks control reactions in a single molecule

Scientists have developed a method to control chemical reactions in a single molecule by applying voltage pulses, resulting in unprecedented selectivity. By fine-tuning the voltage, researchers can interconvert different products formed during the reaction.

Nanoscale observations simplify how scientists describe earthquake movement

Researchers at the University of Illinois used single calcite crystals with varying surface roughness to simplify the physics of fault movement. The study found that friction can increase or decrease with sliding velocity depending on mineral types and environment, providing a fundamental understanding of rate-and-state equations.

NYU Abu Dhabi researchers develop novel 3D atomic force microscopy probes

Researchers have developed novel 3D atomic force microscopy (AFM) probes with improved designs, materials, and production processes. The new probes enable high-resolution, high-speed AFM imaging under air and liquid environments, opening doors for advanced applications in fields like biomedical sciences.

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How ultrathin polymer films can be used for storage technology

Scientists from Martin-Luther-University Halle-Wittenberg discovered that precisely applied mechanical pressure can improve the electronic properties of polyvinylidene fluoride (PVDF) films. The team used atomic force microscopy to control and reorient electrical charges in the material, enabling stable nano-scale structures with high ...

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Using nanodiamonds as sensors just got easier

University of Rochester researchers adapt excited state lifetime thermometry to extract temperatures of nanoscale materials from light emitted by nitrogen vacancy centers in single nanodiamonds. The technique allows for precise measurement of temperature changes on fast time scales and is safe for imaging sensitive nanoscale materials ...

The Diels-Alder reaction, on-surface

Researchers successfully carried out the first on-surface intramolecular Diels-Alder reaction, generating valuable intermediate molecules. This breakthrough allows for a better understanding of the transformation's mechanisms and potential design of new reactions.

Apple iPad Pro 11-inch (M4)

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Speeding up atomic force microscopy

Kanazawa University scientists design a zero-latency amplitude detector for high-speed atomic force microscopy, significantly improving temporal resolution. The new detector enables faster recording of biological processes with higher video frame rates and reduced invasiveness.

Sharpest images ever reveal the patchy face of living bacteria

Researchers have recorded the sharpest images of living bacteria, revealing a complex architecture that makes them harder to kill by antibiotics. The study found that bacteria with protective outer layers may have stronger and weaker spots on their surface.

First evidence of microtubules’ mechanosensitive behavior

A research team led by Associate Professor Akira Kakugo of Hokkaido University has provided direct evidence that microtubules function as mechanosensors, slowing down kinesin movement when bent. This phenomenon is attributed to enhanced interaction energy between kinesin and deformed microtubule structural units.

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Researchers measure the breakup of a single chemical bond

Using advanced microscopy techniques, researchers recorded the breaking of a single chemical bond between a carbon atom and an iron atom on different molecules. The team measured the mechanical forces applied at the moment of breakage, revealing insights into the nature of these bonds and their implications for catalysis.

New super-resolution microscopy method approaches the atomic scale

Scientists at Weill Cornell Medicine developed a computational technique that greatly increases the resolution of atomic force microscopy, revealing atomic-level details on proteins and biological structures. The new method allows researchers to study biological molecules under physiologically relevant conditions, providing high-resolu...

A scanning quantum sensing microscope with nanoscale electric-field imaging

Researchers developed a scanning quantum sensing microscope that maps local electric fields with a spatial resolution of ~10 nm and sensitivity close to an elementary charge. The technique allows for reversible control of single NV's charge states, enabling the purification of NV's electrostatic environment.

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How acidic are atoms?

Researchers at Vienna University of Technology have developed a new microscopy technique that allows for the measurement of atomic acidity on surfaces. This breakthrough enables analysis of catalysts on an atomic scale, which is crucial for improving chemical reactions.

Two-phase material with surprising properties

Researchers at TU Wien have discovered a two-phase material with surprising electro-mechanical properties that change dramatically above a certain temperature. The team found that the crystals responsible for these properties remain electroactive, but the macroscopic behavior disappears due to a loss of contact between crystal grains.

New microscopy concept enters into force

A team led by Alexander Eichler has demonstrated the first scanning force microscope with a vibrating substrate, pushing sensitivity to its fundamental limit. The approach uses a perforated membrane as the 'table' and features an optical interferometer for sensitive measurement.

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High-speed atomic force microscopy visualizes cell protein factories

Researchers use high-speed atomic force microscopy to visualize the structural dynamics and factor pooling of ribosome stalk proteins, shedding light on the translational GTPase factor mechanism. The study reveals two conformations of the stalk protein and provides evidence for a potential role in further stages of protein synthesis.

Quantum light squeezes the noise out of microscopy signals

Researchers at ORNL developed a quantum microscope that measures signals with sensitivity better than classical limits, revealing fine details hidden by noise in microscopy signals. The approach uses squeezed light to reduce noise and achieve higher signal-to-noise ratios.

Apple MacBook Pro 14-inch (M4 Pro)

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'Seeing' and 'manipulating' functions of living cells

Researchers have developed a technique to control and visualize cell function expression at a high level, enabling minimally invasive surgery to living cells. This innovation aims to solve the mystery of life by manipulating cellular functions and visualizing biomolecules.

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Polycatenanes in mesoscale

A Japanese research group led by Professor Shiki Yagai has successfully created polycatenanes, self-assembled molecule rings that can be observed under a microscope. By using atomic force microscopy, they confirmed the structure of poly[22]catenane made up of as many as 22 connected rings, reaching up to 500 nm in length.

Developing new techniques to improve atomic force microscopy

Developing new techniques to improve atomic force microscopy has reduced the noise associated with the technique. By utilizing a piezo component to maintain zero deflection, researchers can record IR signals with improved precision and image smaller sample volumes, like cell membranes.

How to gently caress atoms

Researchers at TU Wien develop a method to study metal oxide surfaces using a single oxygen atom attached to an atomic force microscope tip, allowing for gentle examination of surface structures without altering the atoms. The technique reveals different ways oxygen molecules attach to titanium atoms on the surface.

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Biophysics: Stretching proteins with magnetic tweezers

Researchers create a novel method using magnetic tweezers to study the mechanical forces that activate proteins like VWF, which initiates blood clots. The technique reveals the unfolding of VWF dimers under low forces, shedding light on the first step in blood coagulation.

Scientists explore aged paint in microscopic detail to inform preservation efforts

Researchers used X-ray imaging and nanoscale techniques to analyze the chemical processes involved in aging oil paints. The study found that metal soaps can cause deterioration in artworks, particularly those composed of oil paints. The findings have implications for art conservation and potential solutions to prevent further damage.

Researchers put a new spin on molecular oxygen

A multinational team successfully alters oxygen atoms' charge states and achieves reversible conversion to molecular oxygen using Kelvin probe force spectroscopy. The researchers found that controlled bonding between adjacent oxygen atoms can be induced remotely via surface polarons.

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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Engineers revolutionize molecular microscopy

Engineers developed a novel scanning quantum dot microscopy method that enables the accurate measurement of electrical potentials at molecular resolution. This breakthrough allows for high-resolution images of potential fields, previously unattainable, and opens up possibilities for creating nanostructures via 3D printing.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Uncovering microgel mysteries

A team of scientists at Shinshu University used a newly customized tool to study hydrogel microspheres, observing structural differences that were previously unexplained. The study reveals that the method of production greatly affects the structure and behavior of thermoresponsive microgels.

Virulence factor of the influenza A virus mapped in real-time

The study found that acidic environments make the HA0 molecule flatter and more circular, inducing conformational changes. The researchers used high-speed atomic force microscopy to visualize the structure of HA0 in real-time, paving the way for developing therapeutic approaches against influenza A viruses.

Measuring forces of living cells and microorganisms

A new technique using micropipette force sensors measures the tiny forces exerted by living cells and microorganisms with high precision. The method allows for testing the reaction of cells to environmental factors and has potential applications in biomedicine, such as identifying drugs for infectious diseases.

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Use a microscope as a shovel? UConn researchers dig it

Researchers have discovered that atomic force microscopes can be used to map the interior of materials, revealing patterns and properties previously unknown at the surface. This new technique has the potential to improve the design of computer chips and reduce energy consumption.

Hand-knitted molecules

Researchers from Empa successfully synthesized chain-shaped molecules between two microscopically small gold tips. The properties of the resulting molecule can be monitored in real time during synthesis, enabling the creation of electrically conductive molecules with atomic precision.

Seeing and avoiding the 'blind spot' in atomic force measurements

A team of researchers has discovered a 'blind spot' in atomic force microscopy that can lead to incorrect results due to the use of certain force laws. However, they have also developed a new mathematical method to identify and avoid this issue, safeguarding atomic force measurements from inaccurate results.

Smart data enhances atomic force microscopy

A team at University of Washington demonstrates an innovative approach to bridge AFM and big data, offering better spatial resolution and accuracy. By using sequential excitation strategy, they deduce physical insight from PCA data and speed up analysis by orders of magnitude.

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Cell behavior, once shrouded in mystery, is revealed in new light

University of Missouri researchers have developed a new microscope that allows them to observe individual proteins in an unfrozen sample. This breakthrough enables scientists to predict how cells will behave when new components are introduced, which could lead to the creation of more effective drugs with fewer side effects.

Observing cellular activity, one molecule at a time

Researchers at EPFL have invented a new method to examine protein assembly mechanisms in real time using atomic force microscopy. The technique, which uses pulsed laser light, allows for the observation of dynamic processes that were previously impossible to study.

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Individual impurity atoms detectable in graphene

A team of physicists has successfully imaged individual impurity atoms in graphene ribbons using atomic force microscopy. The technique allowed them to identify boron and nitrogen atoms, expanding graphene's properties for applications like transistors and circuits.