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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Nanoscale observations simplify how scientists describe earthquake movement

Researchers at the University of Illinois used single calcite crystals with varying surface roughness to simplify the physics of fault movement. The study found that friction can increase or decrease with sliding velocity depending on mineral types and environment, providing a fundamental understanding of rate-and-state equations.

NYU Abu Dhabi researchers develop novel 3D atomic force microscopy probes

Researchers have developed novel 3D atomic force microscopy (AFM) probes with improved designs, materials, and production processes. The new probes enable high-resolution, high-speed AFM imaging under air and liquid environments, opening doors for advanced applications in fields like biomedical sciences.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

How ultrathin polymer films can be used for storage technology

Scientists from Martin-Luther-University Halle-Wittenberg discovered that precisely applied mechanical pressure can improve the electronic properties of polyvinylidene fluoride (PVDF) films. The team used atomic force microscopy to control and reorient electrical charges in the material, enabling stable nano-scale structures with high ...

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Using nanodiamonds as sensors just got easier

University of Rochester researchers adapt excited state lifetime thermometry to extract temperatures of nanoscale materials from light emitted by nitrogen vacancy centers in single nanodiamonds. The technique allows for precise measurement of temperature changes on fast time scales and is safe for imaging sensitive nanoscale materials ...

The Diels-Alder reaction, on-surface

Researchers successfully carried out the first on-surface intramolecular Diels-Alder reaction, generating valuable intermediate molecules. This breakthrough allows for a better understanding of the transformation's mechanisms and potential design of new reactions.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Speeding up atomic force microscopy

Kanazawa University scientists design a zero-latency amplitude detector for high-speed atomic force microscopy, significantly improving temporal resolution. The new detector enables faster recording of biological processes with higher video frame rates and reduced invasiveness.

Sharpest images ever reveal the patchy face of living bacteria

Researchers have recorded the sharpest images of living bacteria, revealing a complex architecture that makes them harder to kill by antibiotics. The study found that bacteria with protective outer layers may have stronger and weaker spots on their surface.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

First evidence of microtubules’ mechanosensitive behavior

A research team led by Associate Professor Akira Kakugo of Hokkaido University has provided direct evidence that microtubules function as mechanosensors, slowing down kinesin movement when bent. This phenomenon is attributed to enhanced interaction energy between kinesin and deformed microtubule structural units.

Researchers measure the breakup of a single chemical bond

Using advanced microscopy techniques, researchers recorded the breaking of a single chemical bond between a carbon atom and an iron atom on different molecules. The team measured the mechanical forces applied at the moment of breakage, revealing insights into the nature of these bonds and their implications for catalysis.

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New super-resolution microscopy method approaches the atomic scale

Scientists at Weill Cornell Medicine developed a computational technique that greatly increases the resolution of atomic force microscopy, revealing atomic-level details on proteins and biological structures. The new method allows researchers to study biological molecules under physiologically relevant conditions, providing high-resolu...

A scanning quantum sensing microscope with nanoscale electric-field imaging

Researchers developed a scanning quantum sensing microscope that maps local electric fields with a spatial resolution of ~10 nm and sensitivity close to an elementary charge. The technique allows for reversible control of single NV's charge states, enabling the purification of NV's electrostatic environment.

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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

How acidic are atoms?

Researchers at Vienna University of Technology have developed a new microscopy technique that allows for the measurement of atomic acidity on surfaces. This breakthrough enables analysis of catalysts on an atomic scale, which is crucial for improving chemical reactions.

Two-phase material with surprising properties

Researchers at TU Wien have discovered a two-phase material with surprising electro-mechanical properties that change dramatically above a certain temperature. The team found that the crystals responsible for these properties remain electroactive, but the macroscopic behavior disappears due to a loss of contact between crystal grains.

New microscopy concept enters into force

A team led by Alexander Eichler has demonstrated the first scanning force microscope with a vibrating substrate, pushing sensitivity to its fundamental limit. The approach uses a perforated membrane as the 'table' and features an optical interferometer for sensitive measurement.

Sony Alpha a7 IV (Body Only)

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High-speed atomic force microscopy visualizes cell protein factories

Researchers use high-speed atomic force microscopy to visualize the structural dynamics and factor pooling of ribosome stalk proteins, shedding light on the translational GTPase factor mechanism. The study reveals two conformations of the stalk protein and provides evidence for a potential role in further stages of protein synthesis.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Quantum light squeezes the noise out of microscopy signals

Researchers at ORNL developed a quantum microscope that measures signals with sensitivity better than classical limits, revealing fine details hidden by noise in microscopy signals. The approach uses squeezed light to reduce noise and achieve higher signal-to-noise ratios.

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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

'Seeing' and 'manipulating' functions of living cells

Researchers have developed a technique to control and visualize cell function expression at a high level, enabling minimally invasive surgery to living cells. This innovation aims to solve the mystery of life by manipulating cellular functions and visualizing biomolecules.

Polycatenanes in mesoscale

A Japanese research group led by Professor Shiki Yagai has successfully created polycatenanes, self-assembled molecule rings that can be observed under a microscope. By using atomic force microscopy, they confirmed the structure of poly[22]catenane made up of as many as 22 connected rings, reaching up to 500 nm in length.

Developing new techniques to improve atomic force microscopy

Developing new techniques to improve atomic force microscopy has reduced the noise associated with the technique. By utilizing a piezo component to maintain zero deflection, researchers can record IR signals with improved precision and image smaller sample volumes, like cell membranes.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

How to gently caress atoms

Researchers at TU Wien develop a method to study metal oxide surfaces using a single oxygen atom attached to an atomic force microscope tip, allowing for gentle examination of surface structures without altering the atoms. The technique reveals different ways oxygen molecules attach to titanium atoms on the surface.

DJI Air 3 (RC-N2)

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Biophysics: Stretching proteins with magnetic tweezers

Researchers create a novel method using magnetic tweezers to study the mechanical forces that activate proteins like VWF, which initiates blood clots. The technique reveals the unfolding of VWF dimers under low forces, shedding light on the first step in blood coagulation.

Scientists explore aged paint in microscopic detail to inform preservation efforts

Researchers used X-ray imaging and nanoscale techniques to analyze the chemical processes involved in aging oil paints. The study found that metal soaps can cause deterioration in artworks, particularly those composed of oil paints. The findings have implications for art conservation and potential solutions to prevent further damage.

Researchers put a new spin on molecular oxygen

A multinational team successfully alters oxygen atoms' charge states and achieves reversible conversion to molecular oxygen using Kelvin probe force spectroscopy. The researchers found that controlled bonding between adjacent oxygen atoms can be induced remotely via surface polarons.

Engineers revolutionize molecular microscopy

Engineers developed a novel scanning quantum dot microscopy method that enables the accurate measurement of electrical potentials at molecular resolution. This breakthrough allows for high-resolution images of potential fields, previously unattainable, and opens up possibilities for creating nanostructures via 3D printing.

Garmin GPSMAP 67i with inReach

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Uncovering microgel mysteries

A team of scientists at Shinshu University used a newly customized tool to study hydrogel microspheres, observing structural differences that were previously unexplained. The study reveals that the method of production greatly affects the structure and behavior of thermoresponsive microgels.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Virulence factor of the influenza A virus mapped in real-time

The study found that acidic environments make the HA0 molecule flatter and more circular, inducing conformational changes. The researchers used high-speed atomic force microscopy to visualize the structure of HA0 in real-time, paving the way for developing therapeutic approaches against influenza A viruses.

Measuring forces of living cells and microorganisms

A new technique using micropipette force sensors measures the tiny forces exerted by living cells and microorganisms with high precision. The method allows for testing the reaction of cells to environmental factors and has potential applications in biomedicine, such as identifying drugs for infectious diseases.

Use a microscope as a shovel? UConn researchers dig it

Researchers have discovered that atomic force microscopes can be used to map the interior of materials, revealing patterns and properties previously unknown at the surface. This new technique has the potential to improve the design of computer chips and reduce energy consumption.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Hand-knitted molecules

Researchers from Empa successfully synthesized chain-shaped molecules between two microscopically small gold tips. The properties of the resulting molecule can be monitored in real time during synthesis, enabling the creation of electrically conductive molecules with atomic precision.

Seeing and avoiding the 'blind spot' in atomic force measurements

A team of researchers has discovered a 'blind spot' in atomic force microscopy that can lead to incorrect results due to the use of certain force laws. However, they have also developed a new mathematical method to identify and avoid this issue, safeguarding atomic force measurements from inaccurate results.

Smart data enhances atomic force microscopy

A team at University of Washington demonstrates an innovative approach to bridge AFM and big data, offering better spatial resolution and accuracy. By using sequential excitation strategy, they deduce physical insight from PCA data and speed up analysis by orders of magnitude.

Cell behavior, once shrouded in mystery, is revealed in new light

University of Missouri researchers have developed a new microscope that allows them to observe individual proteins in an unfrozen sample. This breakthrough enables scientists to predict how cells will behave when new components are introduced, which could lead to the creation of more effective drugs with fewer side effects.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Observing cellular activity, one molecule at a time

Researchers at EPFL have invented a new method to examine protein assembly mechanisms in real time using atomic force microscopy. The technique, which uses pulsed laser light, allows for the observation of dynamic processes that were previously impossible to study.

Individual impurity atoms detectable in graphene

A team of physicists has successfully imaged individual impurity atoms in graphene ribbons using atomic force microscopy. The technique allowed them to identify boron and nitrogen atoms, expanding graphene's properties for applications like transistors and circuits.

Sensing interactions between molecules

Physicists and chemists at the University of Münster have developed a microscopic method to image organic molecules with exceptional resolution. The technique uses an atomically defined probe tip that greatly increases imaging resolution by reducing undesired interaction between atoms.

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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Discovery sets new world standard in nano generators

Researchers at the University of Alberta have developed a new way to produce high-density DC current, vastly improving over existing triboelectric nanogenerators. The discovery enables continuous flow of electricity from nanoscale movement and vibration, opening up potential applications in sensors, wearable devices, and more.