Articles tagged with Two Photon Microscopy
SCAPE, a new high-speed 3D microscope developed by Elizabeth Hillman, overcomes major hurdles in biomedical research imaging. It allows for real-time 3D imaging at cellular resolution in behaving organisms, capturing complex dynamics like neurons firing in the brain or cells moving in the zebrafish heart.
A new library of tools called Thunder enables neuroscientists to quickly analyze large amounts of brain activity data, generating unprecedented insights into how the brain works.
Researchers will use photoacoustic microscopy to measure oxygen consumption rates of individual cells, mapping distributions of cellular metabolism. The technology has potential applications in gauging cellular health and metabolic state for stress response and toxicity studies.
A novel imaging technique combines high resolution, high penetration depth, and high imaging speed to capture detailed information from live biological samples without damaging them. The technique uses two-photon excitation in sheet-illumination mode, enabling fast imaging speed and reducing light-induced damage.
Researchers developed a non-invasive ultra-high-speed microscope to visualize brain activity in real-time, recording the firing of thousands of individual neurons in 3D. This technology could help decipher 'miscommunications' in neuropsychiatric disorders like autism and schizophrenia.
Researchers developed a method to stabilize living lung tissue for imaging, allowing observation of live cell interactions and immune responses to lung injury. This breakthrough impacts disease research by enabling scientists to look deeper into physiological aspects of injury and diseases.
Researchers employed intravital two-photon microscopy to study immune cells in mice with viral meningitis. They found that T-cells didn't attack infected cells but instead recruited monocytes and neutrophils, which caused fatal seizures.
Researchers used two-photon microscopy to visualize T lymphocyte infiltration into solid tumours in real-time. T lymphocytes target tumour cells by recognizing the antigen and binding with enzymes, ultimately leading to cell death.
A new scanning microscopy technique, SPIM, combines high spatial resolution with sensitivity to subtle electrical activity, enabling the visualization of both electronic and physical patterns in devices. The method has been successfully validated by comparing its images with atomic force microscopy scans.
Researchers have created a handheld device that uses two-photon microendoscopy to image individual cells in living subjects, enabling insights into cellular behavior and its impact on organisms. The technique has been successfully demonstrated using live mice, providing detailed images of blood vessels in the hippocampus.
Researchers at Cornell University developed a new approach to using quantum dots for biological studies of living animals, achieving high-resolution three-dimensional images inside living tissue. The technique, known as multiphoton microscopy with quantum-dot imaging, outperforms conventional methods by 1,000 times in brightness and re...
Researchers at Max Planck Institute discovered that long-term potentiation in hippocampal neurons is linked to the emergence of new dendritic spines. This phenomenon suggests that structural changes play a crucial role in storing information in the brain.
Researchers at Cornell University discovered that chloroplasts are connected by long, slender tubules, allowing them to exchange proteins and potentially other molecules. This finding reveals a new form of communication between organelles within plant cells.