Articles tagged with Nmr Spectroscopy
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers have developed a method to isolate and separate para and ortho water molecules, which differ in their nuclear spin states. This breakthrough could provide new insights into various phenomena, including the study of interstellar ice and protein structures.
High-field nuclear magnetic resonance spectroscopy (≥ 7.0T) detected abnormalities in the hippocampus of Alzheimer's disease rats, including reduced N-acetylaspartate wave crest, elevated creatine and choline wave crest, and neuronal shrinkage.
A team of engineers has created a portable device for nuclear magnetic resonance (NMR) spectroscopy using minuscule chips, reducing the footprint for multidimensional analysis of molecules. The devices can operate accurately over a wide temperature range and may be assembled into a massively parallel array to accelerate analysis of com...
Researchers have developed a new theory to analyze interacting nuclear spins in solvents, revealing that the Nuclear Overhauser Effect is long-range due to electromagnetic radiation frequency. This breakthrough improves understanding of molecular structures and dynamics, opening up new applications for NMR spectroscopy.
Researchers at Brown University used a novel approach to nuclear magnetic resonance spectroscopy to resolve the key interaction between two proteins. The study reveals that the GroEL chaperone is a permissive captor, allowing the smaller protein to bind at two hydrophobic sites and detach, resulting in conformational heterogeneity.
A chemist at UC Riverside is using advanced spectroscopy methods to verify the presence of pomegranate compounds in juices sold as pomegranate juice. By analyzing unique biochemicals, she aims to detect adulterated products and potentially apply this technology to other food and beverage items.
Researchers explored how changes in water content affect bone's structure and dynamics, revealing dynamical structural changes in collagen. The study's success enables future research into atomic-level behaviors of bone under different conditions.
Researchers have determined the structure of a protein within its natural environment, Escherichia coli, for the first time using nuclear magnetic resonance (NMR) spectroscopy. This milestone advances our understanding of molecular biology and opens new avenues for investigating protein interactions in living systems.
Researchers at the University of Illinois have developed a new technique to determine the atomic-scale structure of membrane proteins using solid-state nuclear magnetic resonance spectroscopy. This breakthrough enables high-resolution structural information, which is crucial for understanding protein function.
Researchers are using solid-state NMR spectroscopy to explore the properties of natural antibiotics called antimicrobial peptides (AMPs), which are produced by virtually all animals. AMPs have shown promise in targeting microbes without harming healthy host cells.
Brüschweiler recognized for fundamental contributions to nuclear magnetic resonance spectroscopy and its applications in protein characterization, leading to a deeper understanding of protein behavior and potential disease treatments.
Martin Saunders will receive the James Flack Norris Award for his seminal contributions to NMR spectroscopy, structures, and rearrangements of carbocations. He developed new methods for studying these highly reactive species, allowing him to discover detailed mechanisms and rates of rapid rearrangement reactions.
The new 800 MHz magnet will enable researchers to study larger and more complex biological systems, including protein folding and complex formation. This advancement is expected to significantly improve understanding of normal biological function and regulation, as well as the development of diseases and drug response.
The National Institute of General Medical Sciences (NIGMS) is supporting the construction of four new 900 MHz NMR magnets, the largest size available. This funding will enable researchers to study the structure and behavior of biological molecules, revealing insights into normal cellular processes and shedding light on diseases.
Researchers developed a new 'ex situ' method to recover high-resolution NMR spectroscopy data from samples in nonuniform fields. This breakthrough extends the use of NMR as an analytical tool, enabling studies on previously inaccessible samples.
The new microfluidic-NMR system enables high-performance capillary electrophoresis separations and simultaneous NMR spectroscopy, facilitating the development of desktop spectrometers. The technology has significant applications in drug discovery and combinatorial chemistry.