Articles tagged with Raman Spectroscopy
The COCOON Lab provides a coordinated suite of microscopes that work together to connect macro-scale observations to findings at the nanoscale. This allows researchers to study biological and industrial materials in unprecedented detail, from the macroscale down to the molecular scale.
Researchers at Texas A&M University develop a laser technique called TRIP to directly measure quantum forces shaping proteins, enabling accurate prediction of how pharmaceutical drugs interact with them. This breakthrough could lead to the design of medicines tailored to specific diseases, revolutionizing precision medicine.
Oxygen isotopes in forsterite affect Raman spectroscopy results by causing frequency shifts, lower symmetry, and peak splitting, leading to broader peaks. The study provides a theoretical framework for better interpretation of spectra data.
Scientists discovered a method to predict cellular protein makeup from Raman light measurements, leveraging the power of Raman spectroscopy. The technique reveals globally coordinated abundance ratios across various conditions, with a core of proteins maintaining stability while smaller groups adapt to environmental changes.
Wiley has released additional data to its IR and Raman spectral libraries, significantly broadening compound coverage. The new release includes mineral spectra from the American Museum of Natural History, supporting researchers in making informed scientific decisions.
Researchers found that pill bugs do not simply incorporate ingested CaCO3 minerals as building blocks. Instead, they actively restructure CaCO3 within their bodies to form their tergite cuticles. This study highlights the biological control underlying mineral formation and provides new insights into biomineralization mechanisms.
A new optical-coupled scanning probe microscope uses a remote liquefaction cryogen-free system to visualize individual atoms and probe electronic and chemical properties without freezing budget. The system achieves stable base temperature and low noise levels, making it ideal for continuous experiments and studies of slow processes.
Rice University scientists create a detailed map of the Alzheimer's brain using hyperspectral Raman imaging and machine learning. The findings show that chemical changes are unevenly distributed across the brain and extend beyond amyloid plaques, revealing broader metabolic differences between healthy and diseased brains.
Wachs was recognized for his work on mixed oxide catalysts that guide the rational design of solid catalysts for air pollution remediation, sustainable energy, fuels, chemicals, and pharmaceuticals. His election to the NAE honors his contributions to chemical engineering and the modern field of operando molecular spectroscopy.
A team of engineers at Universiti Sains Malaysia has developed a novel surface-imprinted polymer grafted onto ordered mesoporous silica, which achieves high selectivity for chloramphenicol removal. The adsorbent demonstrated excellent reusability and thermodynamic properties, making it an efficient solution for water purification.
Researchers developed a new compact Raman imaging system that can differentiate between tumor and normal tissue, offering a promising route to earlier cancer detection. The system uses special SERS nanoparticles to detect faint signals from tumor markers, highlighting spots likely to contain tumor tissue.
Researchers use empress cicada wings as a ready-made nanostructure template to enhance surface-enhanced Raman spectroscopy (SERS) performance. The cylindrical nanostructures separated by five-nanometer gaps amplify Raman scattering signals by a factor of a million compared to non-coated cicada wings.
Researchers at MIT have developed a shoebox-sized device that can measure blood glucose levels using Raman spectroscopy, potentially replacing finger pricks for people with diabetes. The device's accuracy is similar to that of commercially available continuous glucose monitoring sensors.
Wiley has expanded its spectral libraries with major updates to IR, Raman, and LC-MS collections, delivering researchers enhanced capabilities for faster and more confident compound identification. The expansion brings over 9.5 million high-quality spectra, including 1 million IR spectra and 161,000 Raman spectra.
A new analytical tool using Raman spectroscopy enables rapid monitoring of vaccine quality and quantity, with results in 30 seconds or less. The tool operates on the production line, saving time and money in vaccine production.
Scientists at Meijo University developed a new method to synthesize small-diameter single-walled carbon nanowires with a high density of long linear carbon chains. The breakthrough enables researchers to probe the properties of these unstable carbon chains, which have outstanding theoretical mechanical strength and thermal conductivity.
KnowItAll 2026 introduces Trendfinder, a tool that brings Principal Component Analysis (PCA) into the KnowItAll environment, enabling simplified chemometric analysis. The new application also enhances LC-MS and NMR capabilities, providing users with advanced analytical capabilities.
Researchers use surface-enhanced Raman spectroscopy to analyze vaginal fluid biochemical fingerprints, detecting specific bacterial species like Lactobacillus iners. The portable device produces comparable results to high-end lab equipment, suggesting its potential for point-of-care monitoring.
Researchers propose a Coulomb attraction-driven spontaneous molecule-hotspot pairing mechanism to achieve synergistic enhancement of electromagnetic and chemical mechanisms in surface-enhanced Raman spectroscopy. This synergy enables efficient detection of single molecules with improved universality, uniformity, robustness, and stability.
Researchers develop compact, noninvasive imaging system combining LC-OCT and Raman microspectroscopy to examine skin cancer structures and chemical composition. The AI model achieves high classification accuracy for basal cell carcinoma and other types, offering new insights into cancer development and behavior.
Scientists discovered a novel method to synthesize gold-polymer nanocomposites within living E. coli bacteria, creating natural microreactors for complex nanostructure formation. The approach enables spatially controlled and eco-friendly synthesis of functional materials.
Researchers at Macquarie University developed a new technique to narrow laser linewidth by factors exceeding 10,000 using diamond crystals and Raman scattering. This breakthrough could revolutionize quantum computing, atomic clocks, and gravitational wave detection with improved spectral purity.
Researchers at Rice University have developed a new method to fabricate ultrapure diamond films for quantum and electronic applications. By growing an extra layer of diamond on top of the substrate after ion implantation, they can bypass high-temperature annealing and generate higher-purity films.
A team successfully observed hydrogen and deuterium molecules confined within a picocavity, revealing unprecedented detail about their vibrational modes. The study demonstrates a pronounced isotope-dependent effect, highlighting the potential for advanced molecular spectroscopy and nanoscale sensing.
University of Missouri scientists have developed an ice lithography technique that etches small patterns onto fragile biological surfaces without damaging them. The method uses frozen ethanol to protect the surface and apply precise patterns.
A team of researchers at Rice University developed a new strategy for identifying hazardous pollutants in soil using light-based imaging and machine learning algorithms. The approach can detect toxic compounds like PAHs and PACs even when no experimental data is available, addressing a critical gap in environmental monitoring.
Researchers at TU Graz have developed a new method for detecting nanoplastics in transparent body fluids, including urine, tear fluid, and blood plasma. The method uses optofluidic force induction and Raman spectroscopy to determine the size and chemical composition of particles.
A new study reports that Raman spectroscopy, a noninvasive technique, can distinguish between abnormal FCD type II tissue and healthy brain cells with remarkable accuracy. This method could provide real-time guidance for surgeons to more accurately identify and remove affected tissue during surgery.
The new method enables accurate detection of polycyclic aromatic hydrocarbons (PAHs) and their derivatives (PACs) in placental samples, providing critical insights into maternal and fetal health. This breakthrough could inform public health measures and improve fetal and maternal health outcomes.
Goethe University has established a new professorship in experimental physics, solid-state physicist Olena Fedchenko has been appointed to the position. The professorship was made possible by Gisela Eckhardt's €11.5 million bequest.
Osaka University researchers have reported a method that gives high-resolution Raman microscopy images of biological samples, up to eight times brighter than previous methods. This technique uses no stains and doesn't require chemicals to fix cells in position, providing a highly representative view of processes and cell behavior.
Researchers developed a deep learning-based method for identifying 2D materials using Raman spectroscopy, achieving high classification accuracy and reducing manual intervention. The new approach generates synthetic data to enhance datasets, enabling precise material characterization even with scarce experimental data.
Scientists at the University of Tokyo have developed a new system that increases the measurement rate of Raman spectroscopy, a technique used to identify molecules. This improvement enables faster identification of molecules and cells, with applications in biomedical diagnostics and material analytics.
Researchers from Niigata University have developed novel glass-forming liquid electrolytes with high ion conduction and efficiency. These materials offer unique advantages in terms of efficiency and application-specific adaptability, paving the way for next-generation energy storage devices.
A new SERS microfluidic system was developed by Shanghai Jiao Tong University researchers, achieving a detection limit lower than 10 ppt of harmful substances. The system uses femtosecond laser-induced nanoparticle implantation into flexible substrate for sensitive and reusable microfluidics detection.
Researchers developed a thin gold membrane with pores to selectively amplify Raman signals from surfaces, enabling the study of surfaces for the first time. This breakthrough improves the efficiency and degradation behavior of batteries, catalysts, and solar cells.
Researchers developed a simple method to measure nano/microplastic concentrations in soil using spectroscopy, eliminating the need for separation processes. The method uses a wavelength combination of 220–260 nm and 280–340 nm to accurately quantify N/MPs in different soil types.
Researchers developed a technology to detect infectious disease viruses in real-time using a single nano-spectroscopic sensor. The system uses molecular fingerprinting and can detect specific substances with tailored detection, enabling rapid and precise analysis.
Researchers develop innovative treatment to alleviate deleterious effects of hyperkalemia, a disease affecting 350 million people worldwide. The new mineral-based therapy uses ion transfer to flush excess potassium from the body, offering a safer alternative to existing treatments.
Researchers at Bar-Ilan University have developed a highly sensitive plasmonic-based detector for detecting piperidine residue in water, posing a significant health risk. The device uses nanometer-sized holes on a metal surface to amplify light, enabling the detection of low concentrations.
A new excitation method called transient stimulated Raman scattering (TSRS) has been developed to achieve natural-linewidth-limit spectral lines with sub-mM sensitivity. TSRS uses broadband femtosecond laser pulse trains to manipulate vibrational wave packets in the time domain, enabling high-density Raman probes and barcode imaging.
Scientists develop innovative approach for hyper-spectral resolution and high-speed spectral acquisition using amplified femtosecond-pulse bursts. The technique offers high spectral resolution and motion-free scanning, promising applications in gas sensing, chemical analysis, and molecular dynamics tracking.
A new method for phase-modulated stimulated Raman scattering tomography enables rapid, label-free 3D chemical imaging of live cells and tissues. This technique improves lateral resolution and imaging depth compared to conventional methods.
The UK Centre for Multimodal Correlative Microscopy and Spectroscopy (CoreMiS) will enable researchers to analyze environmental samples with unprecedented detail. CoreMiS has already been used to study ancient artifacts, detect pollutants in drinking water, and investigate antimicrobial resistance.
Researchers use water as a nonlinear medium to create a supercontinuum white laser covering an impressive spectral range from UV to far infrared. The resulting ultrabroadband source has potential in ultrafast spectroscopy, hyperspectral imaging, and scientific research.
Researchers developed a novel WGM microprobe to enhance Raman signals by combining surface-enhanced Raman spectroscopy (SERS) and whispering-gallery-mode (WGM) microresonators. The platform enables 2D hyperspectral imaging with signal enhancement, opening opportunities for material analysis and chemical imaging.
Researchers found that adding niobium oxide to silicate glass increases bond density and connectivity, enhancing mechanical and thermal stability. This discovery could lead to the development of innovative glass formulations for various applications, including optics, medicine, and data transmission.
Researchers employed laser-induced breakdown spectroscopy, FTIR, and Raman spectroscopy to analyze gemstones from the Arabian-Nubian Shield. The study distinguished natural gems from synthetics and isolated elements contributing to their quality, shedding light on ancient trade routes.
A novel Raman technique called thermostable-Raman-interaction-profiling (TRIP) allows for label-free and highly reproducible Raman spectroscopy measurements, breaking a 50-year-old challenge. The TRIP method enables the detection of protein-ligand interactions in real-time, potentially shortening drug and vaccine testing timelines.
Researchers developed a polarization-angle-resolved Raman microscope to visualize disorder effects on ferroelectric polarization. The study reveals slow response of nanometer-scale electric polarization, enabling significant charge storage and enhanced dielectric properties.
Researchers created a new method, RESORT, to image and analyze living systems in unprecedented detail. The technique combines benefits of super-resolution fluorescence and vibrational imaging, allowing for high spatial resolution and analysis of complex interactions.
The InVADER Mission successfully deployed a high-tech laser laboratory on the ocean floor, marking a paradigm shift in ocean research and exploration. The Laser Divebot collects compositional data without disturbing the environment, removing the need for physical samples.
A new platform has been established to improve the analysis of dynamic metabolic features in cells. The Raman-based flow cytometry tool allows for the profiling of cell populations without labeling or destroying them, providing a non-invasive big-data type for culture-independent phenomes.
Cooperative transitions occur when molecules shift their structure in synchrony, like a row of dominoes flowing seamlessly to the floor. The collaborative method is fast, energy-efficient, and easily reversible, helping living systems operate quickly and efficiently.
Researchers review combination of instrumentation and computational approaches to coherent Raman scattering (CRS), enhancing signal amplification and breaking cross-section limits. Hyperspectral CRS offers potential for deciphering chemical compositions in complex environments, but requires algorithms for information extraction.
Researchers developed high-throughput Raman microscope for rapid large-area imaging hundreds of times faster than traditional approach. The new technique enables label-free molecular analysis and multiplex chemical imaging, holding promise for efficient medical diagnoses and drug development.
Researchers use red-shifted TERS to track tip-induced molecular configurational changes of a single CO molecule on Cu(100) surface, revealing the weakening of C−O bond and tilting angle.
A new open-access Raman spectral library enables scientists to detect molecular 'fingerprints' of particles and better trace sources of ocean plastic pollution. The database adds 42 polymer types, including those from non-plastic particles, to improve accuracy.
Researchers have developed a new method for detecting ultrafast electronic processes using entangled photons, enabling high-resolution Raman spectroscopy. The technique overcomes the diffraction limit and allows for sensitive detection of molecular excitations on the femtosecond scale.
Researchers at Duke University developed nanorattles that amplify signals from separate biomarkers, allowing for accurate detection of head and neck cancers without biopsies. The technology uses machine learning algorithms to tease apart multiple biomarker signals, making it possible to target multiple diseases simultaneously.