Articles tagged with Medical Journals
Researchers from Jilin University provide a comprehensive overview of brain injury biomarkers, including neuron-specific enolase, ubiquitin C-terminal hydrolase-L1, and neurofilament proteins. These biomarkers can help identify brain injuries and predict disease progression.
A new framework aims to facilitate better communication between authors, reviewers, and readers of observational studies. The proposed guidelines promote the adoption of intervention effects in medical journals, enabling more accurate causal inference.
Researchers identified elevated MALAT1 levels in various blood cancers, correlating with adverse outcomes. MALAT1 promotes cancer cell proliferation, migration, invasion, and metastasis through multiple mechanisms.
Researchers have identified CAR-T cell therapy as a potential treatment for autoimmune diseases such as rheumatoid arthritis, SLE, and type 1 Diabetes Mellitus. Early studies have shown promising results in reducing disease activity and improving patients' quality of life, but long-term data on safety and efficacy is limited.
Researchers identify a promising prognostic biomarker for lung cancer using circulating tumor DNA-based minimal residual disease detection. The study found that this method can effectively guide treatment decisions and predict recurrence risk, potentially modifying the lung cancer treatment paradigm.
Researchers discuss recent advances in brain mapping, emphasizing the need to establish precise neuromodulation paradigms based on individual characteristics. Individualized brain mapping methods have evolved from manual labeling to staining techniques across multiple subjects.
A new study reveals gaps in including migrants and refugees in national data collection systems, hindering their human rights and societies' well-being. The authors propose a roadmap for European health systems to improve data quality and promote equity in healthcare.
A study published in Psychological Medicine found that the widely prescribed sedative alprazolam XR may be less effective than believed, with publication bias inflating its efficacy by over 40%. This suggests caution for patients and clinicians starting a prescription for panic disorder.
The guidance paper outlines reliable methods and research practices for improving evidence syntheses. It emphasizes the need for proper education in methodology and cautions against relying solely on appraisal tools and software programs.
The study found a decreasing trend in the global TBL cancer burden from 1990 to 2019, but regional variations persisted. The burden was highest in upper-middle-income countries and lowest in high-income countries.
The study analyzed historical data on coal miners in China, revealing a strong correlation between raw coal production, mining technology, and CWP incidence. The researchers identified key turning points in disease incidence, linked to changes in diagnostic criteria and labor management, as well as coal industry policy reforms.
Researchers from McGill University and Ontario Tech University examine the drivers of specialty drug diffusion. They propose a framework that suggests clinical studies affect the diffusion through a multi-stage scientific evidence production process. The study finds that marketing activities have no significant effect on prescriptions.
Researchers have developed a new manufacturing pipeline to simplify and advance high-value manufacturing of tissue-compatible organs, reducing costs and increasing efficiency. This breakthrough aims to address the dire need for artificially engineered organs and tissue grafts, potentially saving thousands of lives in the UK.
A Chinese Medical Journal review highlights the health hazards of air pollution, particularly from fine particulate matter (PM2.5), which is associated with increased risks of cardiovascular disease, hospitalization, and respiratory mortality. The study suggests that reducing PM2.5 levels through government interventions and individual...
Researchers found that psilocybin facilitates fear extinction in mice by promoting hippocampal neuroplasticity. The study's results improve our understanding of the restorative effects of psilocybin on the brain and may lead to alternative treatments for PTSD.
The study revealed lower age-standardized rate of NENs incidence in China (1.14 per 100,000) compared to the USA (6.26 per 100,000). The most common sites for primary NEN tumors progressed were found to be the pancreas, stomach, lungs, and rectum.
A University of Cambridge analysis identified 98% of reports from trials evaluating new school-based physical exercise programs as lacking key details about teacher training. The study urged journal editors to update their submission guidelines to encourage better reporting, with seven journals already altered their guidance.
Researchers from China conducted a comprehensive review of dual therapy (DT) for H. pylori eradication, highlighting its high efficacy and patient compliance with minimal adverse events. High-dose DT administered over 14 days has emerged as the most effective treatment option.
A traditional Mediterranean-type diet rich in seafood, fruit, and nuts is associated with a lower risk of dementia. Individuals with higher adherence had up to 23% lower risk compared to those with lower adherence. The study, published in BMC Medicine, analyzed data from 60,298 individuals from the UK Biobank.
A large-scale observational study from China demonstrates a strong link between ideal cardiovascular health and lower mortality rates. Individuals with higher scores on behavioral and medical factors had approximately a 50% lower risk of all-cause, CVD, and respiratory mortality compared to those with lower scores.
Researchers identified key metabolic pathways in tumor-associated macrophages that contribute to cancer development and progression. Targeting these pathways may provide a new perspective for immunotherapy-based cancer treatments.
Despite a significant increase in integrated plastic surgery residency positions, applications have remained unchanged. The number of applicants per available training slot decreased by about half, making it easier for accepted candidates to secure spots.
The EU project CRAFT-OA aims to strengthen institutional publishing using Diamond Open Access model across Europe. The project will enable local platforms and service providers to expand their content services with the aim of networking them with other information systems in science.
The American Society of Anesthesiologists' (ASA) new practice guidelines for monitoring and reversing neuromuscular blockade aim to reduce residual paralysis after general anesthesia. This can lead to decreased postoperative complications such as pneumonia, respiratory arrest, and reintubation.
Researchers analyzed nearly 9,600 patients who underwent nerve decompression surgery for upper extremity conditions and found a higher likelihood of migraine diagnosis. The study suggests a possible biologic and genetic overlap between carpal tunnel syndrome and migraines.
The editorial urges wealthy nations to step up support for Africa and vulnerable countries in addressing past, present, and future impacts of climate change. The climate crisis has destroyed a fifth of the GDP of the most vulnerable countries.
Over 250 health journals globally publish an editorial urging wealthy nations to provide climate justice for Africa, citing severe flooding, increased infectious diseases, and economic devastation. The authors argue that achieving the $100bn climate finance target is now 'globally critical' to forestall systemic risks.
A recent study published in Wilderness & Environmental Medicine reveals a significant gender gap in leadership roles and publishing opportunities within the WMS and its journal. The findings show that women comprise only 10% of board presidents, 18% of recognition awards, and 20% of mainstage presenters.
Valentin Fuster, MD, PhD, is honored with the TCT Career Achievement Award for his transformative work in interventional cardiology and patient care. He has made significant global contributions to cardiovascular medicine.
Dr. Nathan Hogaboom has won the prestigious Ernest Bors, MD Award for Scientific Development for his pioneering work on regenerative rehabilitation research in spinal cord injury. His award-winning study applied novel principles to treat debilitating shoulder pain in wheelchair users with spinal cord injury.
The Journal of Nutrition Education and Behavior has awarded its top honors for 2022 to researchers who developed innovative programs and interventions to promote healthy eating habits. The awards recognize the excellence of articles, research briefs, and educational materials published in the journal.
A Rutgers study reveals that racial and ethnic minority groups were less likely to obtain prescriptions to treat opioid addiction during the COVID-19 pandemic. This trend is particularly concerning, as minority groups face more barriers to healthcare and are already disproportionately affected by the pandemic.
Researchers discuss Hepatitis D's life cycle and interactions with its host, exploring strategies for further research to combat this overlooked virus. HDV coinfects people with hepatitis B, rapidly progressing to liver cirrhosis and cancer if left untreated, with a review published in the Chinese Medical Journal.
Patients with a history of unprovoked venous thromboembolism who stop treatment after negative D-dimer tests experience an eight-fold increased risk of recurrence compared to those on low-dose apixaban. Low-dose apixaban was found safe and effective for these patients
Research published in PLOS ONE reveals women make up approximately a quarter of first authors in The Lancet, JAMA, and NEJM. Despite some progress, no notable improvement was observed between 2002 and 2019, highlighting the persistence of a glass ceiling in academic medicine.
A recent study published in PLOS Biology explores the intersection of open science practices and biosecurity risks, proposing solutions to mitigate catastrophic misuse. The authors argue that controlling access to research materials and software is necessary to prevent the spread of risky information.
A new study found that women's health research is disproportionately focused on reproductive years, particularly pregnancy, leaving few articles on major causes of illness and death. Non-communicable diseases, such as cancer and cardiovascular disease, are poorly covered in women's health publications.
Researchers found that many medical journal websites use third-party tracking, which could facilitate targeted pharmaceutical advertising. This study highlights the need for transparency and regulation in this area.
Predatory academic practices are rising globally, with over 80% of researchers indicating they have used problematic outlets. The IAP report recommends training, responsible publishing policies, and transparency in peer-review systems to combat these practices.
A VA research team found increased risks of mental health disorders, including depression, anxiety, and sleep disorders, in individuals who had COVID-19 infection. The study analyzed medical records of nearly 154,000 patients with COVID-19 and compared them to over 11 million people without COVID-19.
A new Chinese Medical Journal study explores the risks of non-alcoholic steatohepatitis (NASH) turning into liver cancer. Early detection through simple medication and lifestyle changes can prevent NAFLD from progressing to more severe conditions, such as cirrhosis and hepatocellular carcinoma.
A clinical trial found that over half of patients with non-small cell lung cancer (NSCLC) with a HER2 gene mutation had their tumors stop growing or shrink after treatment with trastuzumab deruxtecan. The drug showed durable responses in 54.9% of patients, with median survival period of 17.8 months.
A new study found that depression and anxiety symptoms have doubled in children and adolescents globally during the pandemic. The study recommends prioritizing recovery planning now to mitigate sustained mental health effects.
A systematic evaluation of COVID-19 studies in patients with psoriasis and psoriatic arthritis found high risk of bias and quality issues. The median score for all studies was 47.2% indicating a high risk of bias, mainly due to selection bias.
Researchers compared reporting practices for race, sex, and socioeconomic status in randomized clinical trials published in 2015 and 2019. The study found improvements in reporting these factors over time.
A new study reveals that sleep disorders are a common symptom of multiple system atrophy, with greater severity correlating to more neuronal damage. The research found specific associations between sleep-related symptoms and MSA severity, including the parkinsonism subtype.
Researchers assessed changes in article views of articles published in three leading medical journals since COVID-19 started, finding a significant decline in views. The study reveals that online engagement has been impacted by the pandemic, with many journals experiencing a drop in article views.
Researchers compared medRxiv preprint server studies to subsequent medical journal publications and non-preprint articles. The study found significant impact of preprint sharing on research dissemination during the pandemic.
Researchers at the University of Texas at Austin found that articles published in journals accepting reprint fees are nearly three times more likely to be written by authors receiving industry payments. Journals with higher commercial practices have more author conflicts, suggesting a need for stricter open access publishing.
A new study by The George Institute for Global Health found that prediabetes is associated with a higher risk of cardiovascular disease and death. Researchers analyzed over 10 million people and found that early detection and proper treatment can have significant benefits in reducing the burden of these conditions.
A new study found that online symptom checkers are only accurate about a third of the time, and 'Dr. Google' is often incorrect in its diagnoses. The research also found that triage advice provided more accurate results, but lacked quality control and transparency.
A Queensland University of Technology study proposes a simple 'odds-and-evens' approach to safely relaxing COVID-19 lockdown restrictions. By allowing people to leave their homes based on odd or even house numbers, governments can balance competing priorities and create valuable experimental data.
A study found that children and teens aged 8-18 provide an average of 5 hours per day in caregiving activities, including tasks like medication management and cooking meals. Despite their efforts, many youth feel isolated and undertrained, highlighting the need for training and support.
CMAJ's new editor-in-chief, Andreas Laupacis, outlines three priorities for the journal: publishing research relevant to Canadian physicians, expanding nonresearch sections, and increasing patient involvement. He plans to visit universities and healthcare professionals across Canada to gather ideas on improving healthcare.
A recent study found that women scientists are 21% less likely to author invited commentaries in medical journals compared to their male peers. The disparity grows as women progress in their careers, reaching up to 40% for the most senior authors. This lack of diversity in perspectives can hamper health research progress.
Dr. Andreas Laupacis, a renowned medical leader and researcher, has been appointed as the new editor-in-chief of CMAJ. He aims to increase research impact, enhance health policy voice, and promote medical knowledge.
The Lancet Group's new Diversity Pledge and No All-Male Panel Policy aim to increase the representation of women and colleagues from low-income countries among editorial advisers, peer reviewers, and authors. The policies also commit to reflecting a broader range of voices in communications activities.
A comprehensive analysis of 3,000 clinical studies published across three top medical journals identified nearly 400 established medical practices as ineffective. Cardiovascular disease and public health/preventive medicine were the most commonly represented categories among these reversals.
Richard Horton, Lancet editor-in-chief, will receive the $100,000 Roux Prize for his relentless advocacy on global health issues. The honor recognizes his commitment to advance health internationally and challenge the medical profession.
A new editorial argues that the term 'second victim' unfairly shifts blame from healthcare systems to individual providers. The University of Kentucky's Melissa Clarkson and co-authors advocate for a patient-centered approach, prioritizing cultural changes over institutional scapegoating.