Articles tagged with Open Access
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed a definition for heat waves and found that long-duration heat waves have the greatest impact on mortality, with elderly women particularly vulnerable. The study highlights the need for tailored public health interventions to address heat-related mortality in different cities.
A groundbreaking study published in BMC Medical Genomics found significant changes in gene expression due to cigarette smoke exposure. The research, involving 1,240 individuals, identified over 323 unique genes whose expression levels were correlated with smoking behavior, revealing a sobering link between smoking and gene expression.
Researchers found that obese people preferred public health interventions perceived as non-judgmental and empowering. Participants were less likely to view stigmatizing or shaming approaches as effective. Non-commercial techniques, such as personalised care planning and long-term support systems, were also supported.
Researchers created FucM mouse mutants to investigate the role of the fucose mutarotase enzyme in sexual preference. The study found that female mice with the gene knockout displayed drastically reduced sexual receptivity and altered brain development, leading to masculine-like behavior.
Researchers found that virtual food can elicit comparable emotional responses as real food, including increased heart rate and skin conductance. The study suggests the potential use of virtual reality therapy for evaluating and treating eating disorders.
Researchers found that raising juvenile salmon at 16°C causes skeletal deformities. Fast growth temperatures disrupt bone and cartilage production, leading to increased deformity rates. The study suggests temperature-induced growth is severely affecting osteoblasts and chondrocyte cells.
Researchers found that consuming dark chocolate can significantly reduce systolic blood pressure by 5mmHg, comparable to 30 minutes of moderate exercise. This effect is most pronounced in individuals with high blood pressure, potentially reducing the risk of cardiovascular events by 20% over five years.
Researchers tracked bumblebee movements in Arctic conditions, finding that bees work a day shift and retire before midnight. The study suggests that bees may have an internal sense of time based on light intensity or temperature changes.
A team of researchers discovered the molecular mechanisms governing Gerbera's unique inflorescence structure, characterized by three different flower types. The study highlights an expanded gene family that likely plays a new role in the formation of this complex structure, differing from Arabidopsis species.
A study published in BMC Research Notes found that public health campaigns in Swiss media frequently featured negative threats despite a focus on positive, gain-framed messages. Regional newspapers played a crucial role in reporting the campaign, producing more detailed articles than other media outlets.
A study found that psychotropic medications were associated with 429 adverse drug reactions in Danish children under 17, with serious reactions including birth defects and neonatal withdrawal syndrome. The researchers called for tighter controls on the prescription of these medicines to pregnant women.
Researchers found that breeding males were more aggressive towards neighboring males than strangers, potentially to protect paternity. The study suggests the 'Nasty Neighbor' phenomenon helps limit territorial costs.
Resveratrol supplementation has been shown to decrease energy intake by 13% and increase resting metabolic rate by 29% in mouse lemurs. The study demonstrates the compound's potential effects on obesity therapies, providing novel information on its impact on energy metabolism.
Researchers found Campylobacter jejuni and Chlamydophila psittaci in 69.1% and 52.6% of pigeons in Madrid, respectively. These bacteria can cause diarrhea in humans through aerosols, direct contact, or contaminated food and water.
Researchers discovered damselfish selectively weed algal gardens to promote Polysiphonia growth, reducing competition from other algae. This 'gardening' behavior leads to a mutualistic association between the fish and Polysiphonia, showcasing cultivation mutualism in non-terrestrial habitats.
A new yeast strain, TMB3130, has been developed to ferment pentose sugars, significantly improving aerobic growth rate and biomass concentration. This breakthrough enables the efficient production of ethanol from non-food materials, such as agricultural residues.
The study found that nearly 97.5% of Scotland's adults are at risk for multiple health problems, with low education and socio-economic circumstances being key drivers. The prevalence of these risk factors is particularly high in the most deprived communities, highlighting the need for targeted interventions.
Researchers found that an online self-management tool significantly improved asthma symptoms in those with partly controlled or uncontrolled asthma. The system, which allows patients to measure lung function and receive personalized advice, led to a 80% participation rate in the first three months.
A team of researchers from the University of Liverpool identified a male pheromone called darcin, which attracts females and is responsible for learned preference for specific males in mice. Darcin consistently doubled the time spent near a male's scent and was shown to stimulate female memory and attraction.
The 'manifesto' outlines eight key points, including NTDs are tool ready with cost-efficient interventions, yet tool deficient, requiring sustained international support and community involvement to achieve global NTD control. The authors emphasize the need for urgent, renewed, and innovative efforts to tackle NTDs.
Researchers found that children born to HIV-positive mothers with specific TLR9 gene variants are at a higher risk of acquiring the virus. The study confirms the relevance of innate immunity in perinatal HIV-1 infection and may lead to new therapeutic strategies.
Researchers found a significant increase in male fetal losses following the 9/11 attacks, with fewer boys born in December 2001. The study suggests that psychological shock from the event may have threatened the lives of male fetuses across the US.
A systematic review found that Tai Chi is associated with reduced stress, anxiety, and depression, as well as improved mood and self-esteem. However, the quality of the studies was generally modest, highlighting the need for more high-quality randomized trials to confirm these findings.
Researchers discover that most of the genomic output from dark matter transcripts is associated with existing genes. Only a small percentage of these transcripts remain unexplained and appear to be background noise.
The American Society for Microbiology has launched a new open access online journal, mBio, to publish cutting-edge research in microbiology and related fields. The journal features a wide range of topics, including influenza vaccine strategies, universal vaccines, and fungal diseases.
Researchers found that strenuous exercise like running a marathon shifts the balance between pro- and anti-apoptotic genes, potentially halting cellular suicide. The study suggests that sirtuin proteins may play a key role in this process, offering new insights into the effects of exercise on cell death.
The article describes the publication of four new Neotropical plant species in the genus Solanum, governed by the International Code of Botanical Nomenclature (ICBN). Dr. Sandra Knapp, a leading plant taxonomist, separates the printing process from the publisher, enabling online-only publication while complying with ICBN rules.
A recent survey of e-cigarette users found that the devices are helpful in quitting smoking for most people. However, respondents expressed concerns about potential health risks and the lack of regulation surrounding e-cigarettes. The study highlights the need for further research on the efficacy and safety of e-cigarettes.
Researchers investigated the role of low-frequency auditory spatial cues in barn owls' ability to localize sounds. They found that these cues dominate azimuth representation, while high-frequency cues dominate elevation representation. These findings have implications for understanding sound localization in other species, including hum...
Researchers found that rainfall affects sex ratios in African buffalo, with more males born during rainy seasons. The study suggests the presence of sex ratio genes influencing semen quality and female-biased sex ratios during dry periods.
A recent investigation found that 125 out of 940 completed clinical trials for acute ischemic stroke were not published in full, with some trials involving fewer than 10 patients. The study highlights the importance of publishing trial results to ensure patient safety and inform clinical practice.
Researchers found that martial arts fall exercises can reduce hip impact forces, making them safe for older adults with osteoporosis if precautions are taken. The study suggests that martial arts training could be a viable option for preventing hip fractures in this population.
Researchers developed a novel hybrid of two orchid species, creating a unique scent that attracted a distinct wild bee. The offspring's floral odor was highly attractive to solitary bees unfamiliar with the parent plants' scent.
Researchers found strong correlation between colder weather, low rainfall, and higher prostate cancer rates in the US. The study suggests that persistent organic pollutants may be to blame, with cold weather slowing their degradation.
Researchers found that a Mediterranean diet high in phenols represses pro-inflammatory genes, which could contribute to reduced cardiovascular disease risk. The study also suggests that this diet can alter the activity of immune system cells, leading to a less deleterious inflammatory profile.
Research finds disabled children in the UK face higher levels of poverty and personal and social disadvantage compared to their non-disabled peers. The study, published in BMC Pediatrics, found that households with disabled children are more likely to rely on social security benefits and experience additional financial costs.
Researchers found that earplugs and eye masks improved sleep quality, increased REM sleep, and reduced arousals in ICU patients. The study suggests promoting routine use of these aids to potentially enhance clinical outcomes.
A study published in Tobacco Induced Diseases found that work pressures can actually lower a smoker's nicotine dependence. Employees who experience stress at work are likely to smoke less than they otherwise would, suggesting that heavy workload may drive employees to smoke only in their spare time.
A study published in BMC Biology found that male fallow deer vocalizations contain accurate information about their competitive abilities, which change dynamically with age. The researchers also discovered that the deer's vocal identity changes substantially from one year to the next.
Researchers found that nicotine withdrawal syndrome is more common in agitated smokers than non-smokers, increasing risks of accidental tube removals. The study highlights the need for improved strategies to prevent agitation or treat it earlier in critically ill patients.
Researchers found that most H5N1 outbreaks occurred at sites with temperatures between 0°C and 2°C, where wild waterbirds congregated along freezing fronts. This congregation created ideal conditions for the transmission of the virus within and between species.
A recent study by Zalika Klemenc-Ketis and colleagues suggests that raised carbon dioxide levels in the blood may contribute to near-death experiences. The research found a significant association between high CO2 levels and NDEs, with 11 of 52 cardiac arrest patients reporting the phenomenon.
Researchers have discovered small animals in the Mediterranean Sea that live their entire lives without oxygen and reproduce despite a complete absence of oxygen. These multicellular organisms possess organelles resembling hydrogenosomes found in anaerobic environments, challenging our current understanding of life on Earth.
Researchers have created the first class of reagents to potently and selectively inhibit miRNAs in C. elegans, a widely used model organism. The new reagents efficiently and specifically inhibited targeted miRNA in different tissues, including the hypodermis, vulva, and nervous system.
Research suggests that females initiate courtship in crayfish and send conflicting signals to males via urine sprays. This allows females to gauge male size and strength, ensuring only the fittest males fertilize their eggs.
Researchers found that variations in the giggles' pitch and timbre can encode information about a hyena's age, dominance status, and individual signature. This allows hyenas to establish feeding rights and organize their food-gathering activities.
The European Union-funded Infrafrontier project has expanded its network of partners to include six new countries: Canada, Czech Republic, Austria, France, Italy, and the Czech Republic. This international collaboration aims to create an open-access research infrastructure for high-quality mouse models in biomedical research.
Researchers taught goldfish to associate a light flash with a shock, inducing fear. However, fish injected with lidocaine in the cerebellum showed no fear and returned to normal behavior after the anesthesia wore off. This study suggests that understanding brain processes related to fear may lead to human phobia cures.
A new portable device can determine the strength of alcoholic drinks rapidly and easily, using a simple infrared sensor. The technique has been shown to be just as accurate as traditional lab-based methods and can be used in developing countries.
The study compared two chemical name dictionaries and found that automatic curation with Chemlist outperformed manual curation with ChemSpider. The Chemlist dictionary achieved a higher recall and better F-score, while ChemSpider's precision was higher after filtering and disambiguation.
A study published in PLOS Computational Biology found that patient referrals between hospitals influence the rates of hospital-acquired infections, with University Medical Centers showing higher rates. The authors suggest focusing interventions on central hospitals in the network of patient referrals.
Researchers followed 1162 healthy French men and women for nine years, monitoring plasma selenium concentrations and incidence of dysglycemia. High selenium levels in men were associated with a lower risk of developing dysglycemia, while no such association was found in women.
Researchers developed a 'Braccio di Ferro' robot to assist patients in learning arm movements again. The interactive robot helps patients perform correct movements, promoting motor system learning and improving movement ability.
A study on fruit-flies published in PLOS Biology found that genes beneficial to males are detrimental to females, and vice versa. This genetic conflict maintains genetic variation within species by regulating sex-specific characteristics and strategies, such as resource acquisition for reproduction.
Researchers found stress and poor coping mechanisms are common among people who grind their teeth at night. Stress has been implicated in the development of sleep bruxism, which can lead to tooth wear, sensitivity, and muscle pain.
A study published in BMC Gastroenterology found that thiopurine therapy significantly improved the health-related quality of life of Inflammatory Bowel Disease (IBD) patients. The clinical trial, conducted by Guillermo Bastida and his team, reported a substantial improvement in quality of life after one year of treatment.
Researchers found that the IGF1 gene variant responsible for small size in dogs is closely related to that found in Middle Eastern wolves, supporting an ancient origin. The study also suggests that smaller body size may have been desirable in densely populated agricultural societies where dogs lived indoors or in confined spaces.
Researchers investigating UK samples have found no association between XMRV and chronic fatigue syndrome, contradicting a previous report. The study suggests that CFS may encompass a range of diseases and that further investigations are needed to confirm or rule out an association with XMRV infection.
A systematic review found that neonatal and infant circumcision by trained staff rarely results in problems, with relatively minor adverse events being low among infants under one year old. However, complications are more common when performed by inexperienced providers or with subpar equipment.
Researchers found that patients who walked at least two bouts of 1500 steps each on three days a week reported significantly less arthritis pain and improved physical function. Glucosamine sulphate supplementation also showed benefits, with both groups achieving significant improvement in symptoms.