Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Research suggests that sleep apnea can lead to erectile dysfunction due to chronic intermittent hypoxia. However, treatment with tadalafil can reverse the effects and improve sexual function in mice exposed to CIH for extended periods. Further studies are needed to explore alternative interventions.
A genetic mutation in the Prion Protein Gene is linked to mad cow disease, according to a new study by Kansas State University researcher Juergen A. Richt. The mutation affects less than 1 in 2,000 cattle and can be combated through selective breeding and culling of genetically affected animals.
A study at UT Southwestern Medical Center found that a bacterial molecule must be inactivated, not just killed, for an animal to regain full health after infection. The 'signal' molecule, lipopolysaccharide (LPS), triggers the immune response and causes inflammation, but also suppresses it temporarily.
International researchers establish protocols for reproducible toxicological testing of nanomaterials in cells and animals. The International Alliance for NanoEHS Harmonization aims to improve correlations between in vitro and animal testing.
A team of international researchers formed the International Alliance for NanoEHS Harmonization (IANH) to establish reproducible toxicological testing protocols for nanomaterials. The alliance aims to address key gaps in scientific knowledge and accelerate understanding of nanotechnology's social implications.
A Tel Aviv University study found that two-thirds of cat-dog households reported a positive relationship, while aggression was observed in 10%. Cats and dogs can learn to read each other's body signals, suggesting they may have more in common than thought.
Scientists have identified biomarkers in cattle urine that can indicate the presence and progression of Bovine Spongiform Encephalopathy disease. This discovery may lead to a urine-based test for detecting BSE in live animals, allowing for alternative surveillance procedures and improving breeding stock health.
Researchers have developed a gene therapy that prevents blindness in an animal model of mitochondrial dysfunction. The treatment, which involves allotropic expression of mitochondrial genes, restored normal function to human fibroblasts with mutated mtDNA, effectively rescuing animals from impending blindness.
Researchers report that male and female rufous-and-white wren partners sing duets to keep track of each other when apart. The duets also serve as a form of aggressive territory defense, with birds responding aggressively to rival individuals.
Researchers at Yerkes National Primate Research Center created an animal model to study the effects of chronic stress on behavior, physiology, and reproduction. Corticotropin-releasing factor (CRF) is a key neurohormone involved in stress response, and its increased expression is linked to anxiety, depression, and infertility.
Research found that a specific gene variation associated with pair-bonding in voles also affects human males, leading to weaker relationships and increased marital problems. Women married to men carrying the variant reported lower marital quality without lower satisfaction.
Researchers have found that large flightless birds of the southern continents did not share a common flightless ancestor. Instead, each species lost its ability to fly after diverging from ancestors that had the ability to fly. This challenges the long-held assumption of vicariance and suggests parallel evolution among these bird species.
The Entomological Society of America has named 10 new Fellows, including Dr. Robert N. Coulson, John G. Hildebrand, and Dr. Lawrence A. Lacey, for their outstanding contributions to research and teaching in the field of entomology.
Researchers at Durham University have developed two synthetic molecules that can direct stem cells to 'differentiate' into specific tissue types, improving the reliability of experiments and potentially reducing animal use. The new molecules, EC23 and EC19, are more stable than natural compounds currently used in laboratory research.
New research reveals that wolves prioritize seafood, specifically salmon, over deer when available. The study shows that wolves reduce deer hunting activity and focus on fishing during autumn when salmon is abundant.
A novel 3D ultrasound probe guides catheter procedures with clearer real-time images, eliminating x-ray radiation and contrast agent risks. The device is portable and provides continuous imaging, enabling wider range of interventional procedures.
Male Jamaican anole lizards use visual displays to mark their territory, including push-ups, head bobs, and dewlap extensions, to warn other males away. This behavior helps avoid physical confrontations and establishes dominance before dawn and dusk, when these lizards are most active.
Researchers at UT Southwestern Medical Center discovered that antidepressants need new nerve cells to reduce depression-like behavior in mice. Exercise also stimulates the generation of new nerve cells in the same area. The study suggests a possible mechanism for developing drugs to treat depression by stimulating growth of nerve cells.
Male Anolis lizards engage in push-ups, head bobs, and dewlap extensions to defend their territory at dawn and dusk. This behavior is unique among animals, marking the first recorded use of non-acoustic signaling at these times.
A new test for perfect pitch reveals that many non-musicians have the ability to recognize pitches without musical training. The study found a surprising number of people who unconsciously identified notes even when transposed, indicating true perfect pitch.
Scientists at the University of Pittsburgh Center for Vaccine Research are testing vaccines designed to protect against the deadliest strain of avian flu, H5N1. The $3.6M grant will support animal studies using virus-like particles that could potentially offer enhanced protection against new strains.
Dinoflagellates have evolved a unique way to pack their genetic material into compact chromosomes without using histones. This discovery raises questions about the evolution of chromosomes and whether dinoflagellates once had histones but lost them. The study provides new insights into the biochemical basis of chromosome formation.
Research finds that children exposed to pets, suffering from early respiratory or ear infections, and growing up in large families are more likely to become adult snorers. Additionally, these factors may enhance inflammatory processes and alter upper airway anatomy, increasing the risk of adult snoring.
Researchers at Kansas State University have developed a rapid test that can detect multiple diseases and antibiotic resistance in a single sample, reducing the diagnosis time from days to just 24 hours. The test has the potential to improve clinical diagnosis of animal and human infections, as well as enhance our response to bioterrori...
Researchers at Cold Spring Harbor Laboratory discovered that laboratory rats' brains signal uncertainty when making decisions, reflecting their level of confidence. The study found that rats preferentially abort uncertain trials, indicating that confidence plays a crucial role in guiding behavior.
A recent study suggests that experienced elephant matriarchs give their family groups an edge in periods of famine and drought. The study found correlations between calf survivorship and the movements of the group, with older female members playing a crucial role.
Research suggests that increased testosterone in male mice increases their ability to transmit diseases, driving transmission through close social contact. The study found that treated mice made significantly more contacts with both males and females than untreated mice, leading to a higher risk of disease spread.
Researchers discuss the difficulties in diagnosing and treating Barrett's oesophagus, a pre-cancerous condition often associated with chronic acid reflux. The authors suggest improving detection and treatment by developing standardized indicators, less costly screening methods, and laboratory animal models.
Researchers found that phytoestrogens from soy can cause irreversible changes in the brain's reproductive development, leading to early-onset puberty and symptoms of advanced menopause. The study also shows that these compounds can alter the sex-specific organization of the hypothalamus, a critical region for female reproduction.
Researchers at UCSF have identified a new virus, Avian Bornavirus (ABV), as the cause of Proventricular Dilation Disease (PDD) in parrots and exotic birds. The discovery could have profound consequences on conservation efforts for endangered species like the Spix's Macaw.
Researchers have developed a genetically engineered mouse model of chronic sinusitis, which mimics the disease's symptoms and provides a new tool for studying and treating the condition. The 'stuffy nose' mice suffer from reversible loss of smell due to inflammation, offering hope for developing new therapies.
Recent research reveals that spotted hyenas often hunt alone to avoid feeding competition within their social group and instead opt for solo hunts to ensure individual survival. By doing so, they tap into a previously unknown strategy for increasing their chances of capturing prey.
Recent studies on mice have found six specific chromosomal locations that significantly correlate to the inheritance of high physical activity traits. Furthermore, 17 other genetic locations were identified that also control activity levels through interaction with each other, accounting for approximately 84% of behavioral differences ...
A recent study published in Neuron reveals that the brain's decision-making region encodes information associated with the magnitude and delay of rewards. This finding sheds light on why humans and animals prefer immediate over delayed rewards, known as temporal discounting.
Researchers from the University of Bristol found that mammals have two decision-making systems: a fast-but-inaccurate sub-cortical brain and a slow-but-accurate outer cortex. The study suggests that the older system may still be beneficial in modern situations, potentially preventing atrophy and smaller brains in future humans.
A study by the University of Exeter reveals a disturbing rise in cetacean strandings off Cornwall's coast, with most incidents attributed to bycatch in marine fisheries. The researchers are calling for increased conservation efforts and regulations to safeguard the future of Cornish cetaceans.
Resveratrol slows age-related deterioration and functional decline in mice, improving cardiovascular function, bone health, and motor coordination. However, it does not increase longevity when started at middle age.
A study published in PLOS ONE found that editors' expectations for quality reporting have a strong relationship with journal quality. Italian journals, which lack international standards, perform poorly compared to UK journals, indicating the importance of editorial leadership in promoting high-quality research.
Research reveals that life-extending proteins can have damaging effects on brain cells, depending on the circumstances. The findings suggest a complex role for sirtuins, which can both protect against aging and promote oxidative stress.
A study found that enhanced proteolytic activity in the circulation may be the root cause of diverse metabolic problems. The researchers showed that a drug developed for unrelated purposes was effective in counteracting this mechanism, reversing symptoms of high blood pressure, insulin resistance and immune suppression.
The Conservation Leadership Programme awarded 28 research teams in 14 countries with $475,000 support. Winners focus on protecting endangered species and habitats worldwide, including tigers, hooded cranes, and threatened amphibians.
A newly discovered life history among tetrapods reveals a Malagasy chameleon spends most of its life in an egg, hatching after just 4-5 months. This rapid growth rate is unlike any other known four-legged animal.
A large-scale genome analysis reveals that birds did not evolve from a common ancestor as previously thought, but instead underwent multiple adaptations to diverse environments. The study's results challenge current classifications and provide valuable insights into the evolutionary history of birds.
The Early Bird Project, a five-year study funded by the National Science Foundation, has collected DNA sequence data from 169 bird species. The research revealed that birds adapted to diverse environments multiple times and that distinctive lifestyles evolved independently. The study's findings will be published in Science on June 27.
Fossils of Ventastega, a primitive tetrapod, provide insights into the transition from fish to land animals. The new discoveries show that different parts of the body evolved at different speeds during this process.
A new microfluidic device developed by Georgia Tech engineers can automatically position, image, determine the phenotype of and sort small animals such as Caenorhabditis elegans for genetic studies. The device achieves high accuracy at a rate of several hundred animals per hour, greatly reducing processing time and increasing throughput.
Two alternative test methods, the bovine corneal opacity and permeability (BCOP) assay and the isolated chicken eye (ICE) assay, have been accepted for ocular safety testing. These non-animal tests can identify substances that may cause permanent or severe eye damage, reducing animal use in this area.
The Plant Metabolic Network (PMN) is a web-based resource dedicated to understanding plant metabolism, providing researchers with essential information to engineer crops for food, biofuels, and medicines. The database currently contains over 500 biochemical pathways from 290 plant species.
A new oral formulation of vitamin B12 has shown promise in improving absorption rates without the need for invasive injections. The eligen technology has been tested in animal studies and is currently being conducted in human trials.
Research into crystal meth addiction has been limited to animal studies, but potential therapeutic agents targeting dopamine and non-dopamine systems are in clinical testing. The article highlights the need for accelerated clinical trials to address the public health importance of this issue.
A new family tree of all British birds provides clues about which species might be endangered next, with declining populations clustered together on the same branches. The study found a link between closely related birds and chances of population decline, but also noted that geographical area inhabited by species is not a key factor.
Research from the American Museum of Natural History shows that global warming is causing species in Madagascar's mountainous north to move up tropical mountains as their habitats shift upward. The study found an average shift of 19-51 meters over a decade, linked to temperature increases of 0.1°C to 0.37°C.
Scientists have disrupted malaria parasite transmission in animal tests by blocking potassium channels, preventing the formation of new infectious parasites. This breakthrough could pave the way for new anti-malaria treatments and counteracting the spread of the disease.
Researchers have developed two new methods to better estimate the numbers of European Otters and their effects on fish farming industries. Genetic analyses of faeces can prove a promising approach in investigating otter populations. The information can be used to ensure effective nature conservation by calculating fish eaten per pond a...
Scientists have found a gene, MagA, that allows mammalian cells to produce tiny magnetic particles, making them visible under magnetic resonance imaging (MRI). The gene shows potential as an imaging tool for tracking cells' movement through the body.
Researchers found that only two strains of Salmonella are common in garden birds, which are sensitive to antibiotics. This contrasts with the more resistant strains found in livestock and humans, highlighting the need for alternative approaches to infection control.
A study by California Polytechnic State University researchers has linked Toxoplasma gondii, a parasite typically associated with cats, to marine mammal deaths worldwide. The team discovered that northern anchovies may be spreading the parasite through the ocean's filter-feeding mechanism, posing a potential transmission risk to mammals.
Scientists have identified p16 as a gene that accelerates cellular aging, while p19 slows it down. The study sheds light on the development of aging-related characteristics such as loss of muscle mass and cataracts.
Researchers at University of Washington and Johns Hopkins University propose that shuffling emerged as a precursor to bipedal behavior to conserve metabolic energy. For distances less than 30 feet, shuffling would be efficient, while longer distances would favor all fours.
New research on azhdarchid pterosaurs suggests they were strongly adapted for life on the ground, with features such as long limbs, stiff necks, and padded feet. The study argues that these reptiles were specialized terrestrial stalkers, using their unique anatomy to pick up prey from the ground.