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Ultrapotent compound may help treat C. diff, reduce recurrence

Researchers have created ultrapotent compounds to treat Clostridioides difficile (C. diff), a leading cause of healthcare-associated infections in the US. The compounds show significant advantages over current antibiotics, including minimum inhibitory concentration values as low as 0.003 μg/mL and improved prevention of recurrence.

SourcePurdue University·JournalJournal of Medicinal Chemistry·DateSep 25, 2020

Breakthrough for tomorrow's dentistry

Researchers at Karolinska Institutet have identified all cell populations in mouse teeth and young human teeth, deciphering differentiation pathways of odontoblasts and ameloblasts. The study sheds light on tooth sensitivity and the formation of enamel.

SourceKarolinska Institutet·JournalNature Communications·DateSep 23, 2020

Is rheumatoid arthritis two different diseases?

A new study published in PLOS Medicine suggests that rheumatoid arthritis patients with and without autoantibodies have distinct conditions. Longitudinal data from 1,285 RA patients showed improved disease activity but varying long-term outcomes depending on autoantibody status.

SourcePLOS·JournalPLOS Medicine·DateSep 22, 2020

Wels catfish genome assembled

A research team has successfully sequenced and assembled the Wels catfish genome, which is expected to reveal insights into its remarkable growth rate, appetite, and lifespan. The study's findings will help address bottlenecks in aquaculture and conservation of wild populations.

Fungi in a warmer world

A $1m research project will examine fossilised fungi from 15-17 million years ago to forecast the impact of predicted rises in current global temperature on present day species. The study aims to understand how fungi respond to past warm climates, which could provide valuable information for adapting to climate change.

Southern hemisphere could see up to 30% less rain at end of the century

Climate models suggest that tropical and subtropical southern hemisphere countries, including Brazil, may experience longer droughts and reduced rainfall by the end of the century. The mid-Pliocene period, which occurred 3 million years ago, shares characteristics with modern warming, indicating a possible future scenario.

The brain's memory abilities inspire AI experts in making neural networks less 'forgetful'

Researchers at UMass Amherst and Baylor College of Medicine developed a new method to protect deep neural networks from catastrophic forgetting, inspired by the brain's 'replay' ability. The method, called generative replay, generates high-level representations of previously seen data, preventing the network from forgetting earlier lea...

SourceUniversity of Massachusetts Amherst·JournalNature Communications·DateSep 17, 2020

Brazilian researcher creates an ultra-simple inexpensive method to fabricate optical fiber

A novel process for fabricating special optical fiber has been developed by Brazilian researcher Cristiano Cordeiro, simplifying the conventional method that requires costly equipment. The new process can be completed in under an hour and is significantly cheaper, enabling more researchers to produce their own optical fiber.

Your paper notebook could become your next tablet

Purdue engineers have developed a simple printing process that renders any paper or cardboard packaging into easy-to-use human-machine interfaces. The technology allows for the fabrication of vertical pressure sensors without external batteries, harvesting energy from user contact.

SourcePurdue University·JournalNano Energy·DateSep 1, 2020

Scientists unlock crops' power to resist floods

Researchers have discovered a way to make staple foods resistant to flooding triggered by climate change. By manipulating enzymes that control plant responses to low oxygen levels, scientists hope to create flood-tolerant crops that can help mitigate the devastating impact of extreme weather events on food production.

SourceUniversity of Sydney·JournalProceedings of the National Academy of Sciences·DateAug 31, 2020

Being a selfish jerk doesn't get you ahead, research finds

Two 14-year longitudinal studies found that people with disagreeable personality traits, such as being combative and manipulative, are not more likely to achieve power than those who are nice. In contrast, extroverts were the most likely to advance in their organizations based on sociability, energy, and assertiveness.

SourceUniversity of California - Berkeley Haas School of Business·JournalProceedings of the National Academy of Sciences·DateAug 31, 2020

Giant nanomachine aids the immune system

Researchers have created an atomic structure of the peptide-loading complex, a biological nanomachine that loads antigens onto MHC molecules. This allows for detailed molecular dynamics simulations to study its dynamics and mechanism, enabling targeted interventions in immune processes.

SourceRuhr-University Bochum·JournalProceedings of the National Academy of Sciences·DateAug 28, 2020

Insect wings inspire new ways to fight superbugs

Researchers have discovered how insect wing-inspired nanomaterials kill bacteria on contact, with patterns that stretch, slice or tear cells apart. The findings hold promise for developing low-cost and scalable anti-bacterial surfaces for use in implants and hospitals to combat deadly superbugs.

SourceRMIT University·JournalNature Reviews Microbiology·DateAug 18, 2020

Discovered a new method of biofortification that transforms leaves into nutrient stores

A team of researchers at CSIC and CRAG has discovered a new method to transform chloroplasts in leaves into chromoplasts, which produce high levels of carotenoids. This process can increase the nutritional value of crops and provide a sustainable source for the food and cosmetic industries.

SourceCentre for Research in Agricultural Genomics (CRAG)·JournalProceedings of the National Academy of Sciences·DateAug 17, 2020

KIST finds a strong correlation between ultrasonic stroke rehabilitation treatment and brain waves

Researchers at KIST found a strong correlation between ultrasonic stroke rehabilitation treatment and changes in delta brain waves, which can improve motor functions. The study lays the foundation for developing a patient-specific stimulation method to estimate therapeutic effects.

SourceNational Research Council of Science & Technology·JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering·DateAug 12, 2020

Group produces materials via self-organization in chemical systems

The Campinas Electrochemistry Group produces novel materials through self-organization in chemical systems. The group aims to achieve a deeper understanding of these processes to control their growth and structure. This research has the potential to lead to advancements in catalytic efficiency, selectivity, and material properties.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalThe Journal of Physical Chemistry C·DateAug 12, 2020

SDSU professor finds after-hours cannabis use has no impact on workplace performance

A recent study by Dr. Jeremy Bernerth and H. Jack Walker found that using cannabis after work hours does not compromise job performance as assessed by supervisors. In fact, the researchers suggest that after-hours cannabis use may offer some work-related benefits, such as helping employees relax and restore energy after a long day.

SourceSan Diego State University·JournalGroup & Organization Management·DateAug 11, 2020