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Butantan Institute’s dengue vaccine protects 79.6% of those vaccinated, study shows

The Butantan-DV vaccine has been shown to be effective in preventing dengue development in 79.6% of vaccinated individuals, regardless of age group or prior exposure history. The vaccine also demonstrated safety for all participants, with mild to moderate side effects reported.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateFeb 1, 2024

Ethnic disparities in cancer mortality in the capital and northeast of the State of São Paulo, Brazil

Cancer kills more Black people than White individuals in the Barretos region, whereas in São Paulo city, it is the opposite, according to a study published in Cancer Causes & Control. The disparity is most pronounced for breast and cervical cancer among Black women.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalCancer Causes & Control·TypeData/statistical analysis·DateJan 30, 2024

Nearly two-thirds of low-risk pulmonary embolism patients are hospitalized after ED visit

A study of over 1.6 million ED visits found that nearly two-thirds of low-risk pulmonary embolism patients were hospitalized, despite evidence suggesting safety in outpatient management. Researchers suggest further investigation into ED triage decisions to improve appropriate use of outpatient care.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateJan 29, 2024

Obesity and alcohol are contributing to increases in bowel cancer rates among young adults

Experts predict a significant increase in bowel cancer death rates among young adults in the EU and UK, driven by rising obesity and heavy alcohol consumption. Death rates are predicted to rise by 26% in men and nearly 39% in women in the UK, with similar increases seen in Italy and other European countries.

SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·TypeData/statistical analysis·DateJan 28, 2024

Car accidents, accidental overdoses account for majority of accidental deaths among U.S. soldiers deployed in Afghanistan/Iraq wars—but death rates differ by time since deployment, age, and gender

Rates of fatal motor vehicle accidents were highest among military members immediately following their return from deployment, while the highest rates of fatal accidental overdose deaths occurred later in postdeployment life. Younger soldiers between 18-24 years old were at highest risk for MVA and accidental overdoses.

SourceBoston University School of Public Health·JournalAnnals of Epidemiology·TypeObservational study·DateJan 25, 2024

Risk of death during heatwaves in Brazil linked to socioeconomic factors

A new study found that heatwaves in Brazil are disproportionately affecting female, elderly, Black, Brown, and low-education individuals, resulting in a staggering 48,075 deaths between 2000 and 2018. The research highlights the need for targeted efforts to reduce mortality rates during future heatwaves.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateJan 24, 2024

Death rate higher than expected for patients with functional, nonepileptic seizures

A Michigan Medicine-led study found that patients with functional seizures have a death rate almost 2.5 times higher than expected, comparable to epilepsy and serious mental health conditions. The study highlights the need for improved access to holistic, multidisciplinary treatment for functional neurological disorders.

SourceMichigan Medicine - University of Michigan·JournalNeurology Clinical Practice·TypeObservational study·DateJan 24, 2024

Understanding healthy and happy expectancy in former soviet countries

Researchers found that populations in Central Asian countries have significantly higher healthy and happy life expectancies compared to Russians, despite lower socioeconomic development. This challenges the understanding of health and raises questions about contributing factors to healthier lives in these communities.

SourceSophia University·JournalPopulation Research and Policy Review·TypeData/statistical analysis·DateJan 11, 2024

About 22 high school age adolescents died each week from overdoses in 2022, driven by fentanyl-laced prescription pills

A new study found that fentanyl-laced prescription pills are driving a surge in overdose deaths among high school age adolescents in the US. The death rate for this group has increased to 5.2 per 100,000, with Arizona and Colorado experiencing rates double the national average.

SourceUniversity of California - Los Angeles Health Sciences·JournalNew England Journal of Medicine·TypeData/statistical analysis·DateJan 6, 2024

Doctor Who festive specials linked to lower death rates

A new Doctor Who episode aired during the festive period is associated with lower death rates in the subsequent year across the UK. The study highlights the positive effect doctors can have when working during the holiday season, suggesting that watching a doctor care for people may encourage health-seeking behavior.

SourceBMJ Group·JournalThe BMJ·TypeCommentary/editorial·DateDec 18, 2023

Few patients receive opioid agonist therapy after opioid overdose, despite benefits

Only 4.1% of hospital encounters for opioid overdoses led to opioid agonist therapy (OAT) initiation within a week of discharge from hospital, highlighting missed opportunities to prevent future mortality and morbidity related to opioid use disorder. Studies show that prompt OAT initiation in the emergency department is crucial to redu...

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·TypeObservational study·DateDec 18, 2023

Air conditioning has reduced mortality due to high temperatures in Spain by one third

A study published in Environment International found that air conditioning reduced heat-related mortality in Spain by up to 31.5%, while heating systems contributed to a decrease of 50.8% in extreme cold-related fatalities. However, the effect may be attenuated by an ageing population.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·TypeData/statistical analysis·DateDec 18, 2023

Deaths from heart valve infections drop across U.S. overall, but surged among young adults

A new study found that deaths from infective endocarditis decreased overall in the US, but rose sharply among people ages 25-44, likely linked to the opioid crisis. Researchers call for more investigation into the trends and recommend comprehensive care plans including substance use disorder screening and treatment.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateDec 13, 2023

Even small amounts of physical activity could be valuable in late-stage lung cancer

New research found that less than five minutes of daily physical activity can be beneficial for people living with inoperable lung cancer, reducing mortality rates by 60% compared to those who were largely inactive. Healthcare providers should investigate a person's levels of physical activity in early management of the disease.

SourceCurtin University·JournalJournal of Clinical Medicine·TypeRandomized controlled/clinical trial·DateDec 7, 2023

Trends in adult smoking prevalence

A study of 353,000 US adults found a decline in smoking prevalence from 2011 to 2022, except for those 65 and older. The greatest gains in reducing smoking-attributable morbidity and mortality can be achieved by targeting individuals with low socioeconomic status.

SourceJAMA Network·JournalJAMA Health Forum·DateDec 1, 2023

Choice of intravenous fluid therapy could improve survival in critically ill patients

A new meta-analysis found that intravenous fluid therapy using balanced solutions can reduce the risk of in-hospital death in critically ill patients by four percent. Balanced solutions are more closely matched to human blood chemistry than commonly used saline, and may be associated with lower mortality rates.

SourceGeorge Institute for Global Health·JournalThe Lancet Respiratory Medicine·TypeMeta-analysis·DateNov 30, 2023

Prioritizing circulation before the airway in trauma may improve outcomes for patients with massive bleeding

A literature review found that prioritizing circulation before the airway in trauma patients with major blood loss leads to improved outcomes, including lower mortality rates. This approach, known as CAB, has gained acceptance over the ABC model and is now being recommended by the American College of Surgeons.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·TypeLiterature review·DateNov 28, 2023

Colorectal cancer in sub-Saharan Africa: Lack of basic care is costing lives

A new study found that most people with colorectal cancer in sub-Saharan Africa receive inadequate treatment, leading to significantly improved life expectancy through simple measures. The mortality rate is up to 3.5 times higher in regions studied compared to countries with medium HDI scores.

SourceMartin-Luther-Universität Halle-Wittenberg·JournalJournal of the National Comprehensive Cancer Network·TypeObservational study·DateNov 22, 2023

Chinese Medical Journal article reveals key insights on the trends of asthma mortality

A recent study analyzed asthma mortality rates in China and the US from 1990 to 2019, revealing substantial differences in mortality rates and risk factors. The study found that smoking was a leading risk factor for asthma mortality in China, while high body mass index (BMI) was a larger public health challenge in the US.

SourceCactus Communications·JournalChinese Medical Journal·TypeData/statistical analysis·DateNov 22, 2023