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Study reports ibrutinib and venetoclax combo effective as front-line therapy for select chronic lymphocytic leukemia patients

Researchers found that the combination of ibrutinib and venetoclax was highly effective in achieving complete remission with undetectable minimal residual disease in high-risk CLL patients. The study also showed that this combination therapy had no new toxic effects compared to individual agents.

SourceUniversity of Texas M. D. Anderson Cancer Center·JournalNew England Journal of Medicine·DateMay 29, 2019

New boost for ToCoTronics

The University of Würzburg's ToCoTronics SFB has secured additional funding to continue research on topological materials. The project aims to optimize material quality, generate new interfaces with superconductors and ferromagnets, and explore spin-orbital coupling with Coulomb interaction.

UT Institute of Agriculture awarded nearly $1 million to study woody biomass feedstock logistics

A team at UTIA will determine key parameters for efficient logistics systems using innovative approaches, including evaluating alternative preprocessing technologies and modeling techno-economic analyses. The study aims to expedite commercialized cellulosic biofuel production by balancing cost and quality in feedstock logistics.

The smell of dark chocolate, demystified

Researchers identified volatile compounds contributing to dark chocolate's distinctive aroma, including β-ionone and other essential components. By quantifying these substances using stable isotope dilution analysis, the team successfully reconstructed the scents of two dark chocolates with remarkable accuracy.

SourceAmerican Chemical Society·JournalJournal of Agricultural and Food Chemistry·DateMay 8, 2019

Mental disorders more common in people who live alone

Research found that living alone is positively associated with common mental disorders across all ages and sexes. The prevalence of people living alone was linked to an increased risk of mental health issues, with loneliness explaining 84% of the association.

SourcePLOS·JournalPLOS ONE·DateMay 1, 2019

Biomimicry of basic instinct

Chemical engineers at the University of Pittsburgh have developed a system that mimics feeding, fighting, and fleeing responses in microbial particles. The system uses catalyst-coated sheets to create chemical gradients, allowing particles to respond to their environment and interact with each other.

SourceUniversity of Pittsburgh·JournalProceedings of the National Academy of Sciences·DateApr 25, 2019

Irregular schedules raise risk of injury for miners working long hours

Researchers from the University of Illinois at Chicago found that injured miners who worked shifts longer than 9 hours tended to have irregular schedules or less than two years on the job. Long work shifts were associated with a 32% increased risk of injury resulting in death and a 73% increased risk of multiple worker injuries.

SourceUniversity of Illinois Chicago·JournalOccupational and Environmental Medicine·DateApr 15, 2019