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How neuroimaging can be better utilized to yield diagnostic information about individuals

Researchers from Dartmouth and University Medicine Essen found that strong links between brain measures and traits can be obtained when machine learning algorithms are utilized. This approach allows for high-powered results from moderate sample sizes, opening up studies of many traits and clinical conditions previously inaccessible.

SourceDartmouth College·JournalNature·TypeCommentary/editorial·DateMar 14, 2023

Any regular physical activity at any age linked to better brain function in later life

A long-term study found that regular leisure time physical activity at any age is associated with better brain function in later life. Maintaining an exercise routine throughout adulthood was particularly beneficial for preserving mental acuity and memory. The study, which included over 1,400 participants, showed that being physically ...

SourceBMJ Group·JournalJournal of Neurology Neurosurgery & Psychiatry·TypeObservational study·DateFeb 21, 2023

What is clinically meaningful to slow Alzheimer’s progression?

The work group reframed what is clinically meaningful to slow Alzheimer's disease progression, including the need for combination therapies and realistic expectations of benefits and risks. Slowing brain deterioration by four to six months in early stages may preserve function, leading to meaningful outcomes for patients and families.

SourceMayo Clinic·JournalAlzheimer s & Dementia·DateFeb 7, 2023

New smartphone app designed by University of Toronto researchers shown to significantly improve memory recall

Researchers developed HippoCamera, a new smartphone app that significantly improves memory recall by boosting attention to daily events. Users record videos and audio descriptions of everyday experiences, which are then replayed to reinforce memory consolidation.

SourceUniversity of Toronto·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJan 16, 2023

The major chord that cures nightmares

A new therapy combining Imagery Rehearsal Therapy with Targeted Memory Reactivation has been shown to significantly reduce nightmare frequency and increase positive dreams in patients. The treatment, which involves associating a major piano chord with positive scenarios, resulted in lasting benefits even three months after the experiment.

SourceUniversité de Genève·JournalCurrent Biology·TypeNews article·DateOct 27, 2022

Video games offer the potential of “experiential medicine”

Scientists at UC San Francisco's Neuroscape Center have developed video game interventions that improve key aspects of cognition in aging adults, including short-term memory, attention and long-term memory. The games use adaptive closed-loop algorithms to challenge players, keeping them engaged while adapting difficulty levels.

SourceUniversity of California - San Francisco·JournalProceedings of the National Academy of Sciences·DateOct 3, 2022

Fitness trackers reveal links between exercise, memory, and mental health

A new study from Dartmouth College found that specific intensities of exercise over a long period are associated with different aspects of memory and mental health. Participants who exercised at moderate intensities performed better on episodic memory tasks, while those who exercised at high intensities did better on spatial memory tasks.

SourceDartmouth College·JournalScientific Reports·TypeExperimental study·DateSep 15, 2022

Making a memory positive or negative

Salk researchers identify neurotensin as a key molecule in the brain's valence assignment process, which associates good or bad feelings with memories. The discovery could lead to a better understanding of why some people retain more negative emotions than positive ones, and may pave the way for new therapeutic targets.

SourceSalk Institute·JournalNature·DateJul 20, 2022

Research probes how people control unwanted thoughts

A new study published in PLOS Computational Biology suggests that proactively avoiding associations can help prevent the repetitive looping of unwanted thoughts. Researchers found that most people use reactive control, which can strengthen unwanted thoughts, but also discovered that preemptive control can partially mitigate this effect.

SourcePLOS·JournalPLOS Computational Biology·TypeExperimental study·DateJul 14, 2022

Where the mind is without fear: Scientists discover mechanism behind the chemically induced suppression of fearful memories

Researchers at Tokyo University of Science identify brain regions and signaling pathways involved in fear extinction via delta receptor activation. The study suggests a potential therapeutic agent for post-traumatic stress disorders by suppressing fearful memories.

SourceTokyo University of Science·JournalFrontiers in Behavioral Neuroscience·TypeExperimental study·DateApr 25, 2022

Association of subjective memory complaints with structural brain abnormalities, cognitive decline among older adults

Researchers found a strong association between subjective memory complaints and larger white matter hyperintensity volumes, indicating abnormal brain structure. The study also showed faster cognitive decline among those with subjective memory complaints, highlighting their importance as an early sign of cognitive impairment.

SourceJAMA Network·JournalJAMA Network Open·DateApr 15, 2022

Scientists pick up the 'slack' on describing the brain networks behind motor function

A new study by Ritsumeikan University reveals that whole-body dynamic balance training increases brain connectivity and improves motor learning. The research found significant changes in brain activity associated with offline learning, opening up new avenues for studying neural networks during natural tasks.

SourceRitsumeikan University·JournalMedicine & Science in Sports & Exercise·TypeExperimental study·DateNov 22, 2021

Altering traumatic memories

Texas A&M researchers have developed a method to indirectly retrieve and weaken fear memories, which could lead to more effective therapy for treating trauma. By reactivating traumatic memories through conditioning procedures, scientists can make them vulnerable to disruption.

SourceTexas A&M University·JournalNature Neuroscience·DateApr 8, 2021

Paper: Emotionally appealing ads may not always help consumer memory

A new study by Hayden Noel found that emotionally arousing advertisements can have a negative effect on immediate memory but a positive effect on delayed memory if the level of emotional arousal is congruent with the ad's claims. The research has practical implications for advertisers seeking to develop effective message strategies.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalInternational Journal of Advertising·DateJan 7, 2021

Sport and memory go hand in hand

Neuroscientists at UNIGE discover that intense physical exercise improves memory and brain activation, particularly in young individuals. Regular sports activity can potentially enhance learning and reduce the risk of neurodegenerative diseases like Alzheimer's.

SourceUniversité de Genève·JournalScientific Reports·DateSep 23, 2020

Protein 'chameleon' colors long-term memory

Researchers at Rice University and UTHealth have discovered how a chameleon-like protein, CPEB3, interacts with actin filaments in neurons. This interaction enables the protein to adapt its binding sites to either SUMO or actin, allowing it to form long-lived aggregates that store memories.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateAug 24, 2020

Dreaming with purpose

Adult-born neurons in the hippocampus play a crucial role in memory consolidation during REM sleep, according to a study published in Neuron. The researchers found that activity in these neurons is necessary for memory consolidation and that synaptic changes occur during learning, enabling memory formation.

SourceUniversity of Tsukuba·JournalNeuron·DateJun 5, 2020

Certain personality traits may affect risk of 'pre-dementia'

A study of 524 adults aged 65+ found that openness was linked to a 6% reduced risk of motoric cognitive risk (MCR), while neuroticism increased the risk of non-amnestic MCI. Personality traits played an independent role in pre-dementia syndromes, emphasizing their importance in dementia risk assessment.

SourceWiley·JournalJournal of the American Geriatrics Society·DateJun 3, 2020

Memory games: Eating well to remember

A study of 139,000 older Australians found strong links between certain food groups, such as fruit, vegetables, and protein-rich foods, and reduced memory loss and comorbid heart disease. Age-specific dietary guidelines may be necessary to prevent cognitive impairment in older populations.

SourceUniversity of Technology Sydney·JournalInternational Journal of Public Health·DateFeb 17, 2020