A study combining disulfiram (Antabuse) with buprenorphine found that participants who received both experienced longer periods of cocaine abstinence and achieved continuous abstinence sooner than those receiving only buprenorphine. No significant differences were observed in opiate abstinence between the two groups.
The National Institute on Drug Abuse's Principles of Drug Addiction Treatment outline essential components of effective treatment based on 30 years of research. The guide highlights the importance of individualized approaches and treatment effectiveness.
Researchers have identified two brain chemicals, delta-FosB and GluR2, as major contributors to the addiction process. The study found that delta-FosB increases sensitivity to cocaine reward by activating genes involved in glutamate receptors, leading to compulsive behavior.
The National Institute on Drug Abuse (NIDA) is hosting a two-day national conference to discuss the latest scientific research on nicotine addiction. The conference will highlight the behavioral and neurobiological bases of nicotine addiction, as well as state-of-the-art treatment strategies and prevention methods.