Articles tagged with Depression
Researchers have identified 19 genes and 25 corresponding proteins that may contribute to the cause of depression. These findings offer promise as potential targets for new depression treatments and could serve as biomarkers for depressive symptoms.
A study of over 42,000 children found that mothers who took antidepressants during pregnancy were more likely to have children with affective disorders, but not due to the medication itself. The research suggests that parental mental illness may be the underlying cause.
A study found that cells from people with major depressive disorder (MDD) have accelerated DNA methylation clocks, indicating an increased risk of mortality. The researchers discovered that these changes persisted even after accounting for lifestyle factors, suggesting a potential biological mechanism underlying the condition.
A new study by UMass Amherst researchers found that couples where one partner is responsive and supportive can maintain better relationship quality despite the other's depression or external stress. The study involved over 200 newlywed couples and found that responsiveness was associated with improved relationship outcomes.
A new study from Aarhus University shows that eight weeks of training in compassion can significantly improve the well-being of relatives. The training helps them deal with difficult emotions and life events, reducing symptoms of depression, anxiety, and stress.
Cells from depressed individuals have higher rates of methylation at specific DNA sites, accelerating their cellular age by approximately two years compared to healthy controls. This accelerated aging is linked to increased mortality risk, as measured by the GrimAge clock.
A recent study by Syracuse University researchers found that EMS workers are three times more likely to experience mental health issues such as depression and posttraumatic stress disorder. Daily mental health symptoms can be reduced through recovery activities like exercising, socializing, and finding meaning in challenges.
A small study found that exposure to phthalates and bisphenols, commonly found in plastics, may contribute to lower progesterone levels during pregnancy and an increased likelihood of developing postpartum depression. Reducing exposure to these chemicals could be a potential avenue for preventing postpartum depression.
Researchers at the University of Helsinki found that depression alters the way the brain processes visual information, with depressed individuals perceiving contrast as stronger. The study used two visual tests to compare brain function in patients with depression to those without.
Researchers identified a novel neural circuit that mediates the reciprocal control of feeding and psychological states in mouse models. Correcting this circuit eliminated anxiety, depression, and reduced body weight in obese mice.
A new study by Anglia Ruskin University found that women with sensory loss are more than twice as likely to report depression and anxiety as men. Women with dual sensory impairment were almost three and a half times more likely to experience depression.
Research suggests non-drug therapies like exercise and social interactions may reduce symptoms of depression in people with dementia. These interventions are found to be as or more effective than drugs in treating depression, suggesting a shift towards 'social' prescribing.
A multinational study of nearly 200,000 people found significant sex-dependent differences in the genetics of schizophrenia, bipolar disorder, and major depressive disorders. The findings suggest that interactions between genes and sex may affect disease risk and progression.
A study analyzing metaphors used by people with severe depression in blogs reveals the importance of social factors, surroundings, and medical practice. The research also highlights the usefulness of blogs as an outlet for expressing and understanding depression experiences.
A study by Thomas Jefferson University found that 87% of incoming medical students reported imposter syndrome, a mental health challenge linked to depression, anxiety, and self-sabotage. The researchers suggest that supportive feedback, collaborative learning, and individual counseling can help alleviate imposter syndrome.
A meta-analysis of over 53,000 patients found no evidence that beta blockers increase the risk of depression or most other psychiatric symptoms. However, sleep disturbance was linked to treatment with beta blockers.
A systematic review of 65 studies reveals that 1 in 5 healthcare workers experienced depression, anxiety, and/or PTSD during the pandemic. The highest pooled rates were found in Middle East countries.
A six-week training program improved emotional resilience in veterans by increasing confidence in regulating emotions and reducing symptoms of anxiety and depression. Brain function changes also occurred, with reduced crosstalk between brain regions involved in emotional processing.
Researchers have identified ezogabine, a drug that opens potassium channels in the brain, as a promising new approach to treating depression. The study showed significant improvements in depressive symptoms and anhedonia in patients with depression.
A new Northwestern University study finds that trained paraprofessionals delivering cognitive-behavioral therapy can reduce depressive symptoms in pregnant women as effectively as mental health professionals. This approach may help address the growing need for treatment and alleviate the burden on overwhelmed healthcare providers.
A new study found that people with depression and anxiety may experience dementia symptoms about two years earlier than those without these conditions. Those with bipolar disorder or schizophrenia may start experiencing symptoms three to seven years earlier.
Research suggests that cognitive behavioral therapy (CBT) can help unemployed individuals find a new job or transition to full-time work within 16 weeks. The treatment also improves productivity and reduces negative beliefs associated with depression.
Researchers found that training primary care physicians in depression recognition and medication treatment can prevent suicide, often halving the risk. Reducing access to lethal methods, such as firearms, is also crucial in preventing suicidal behavior.
A study of over 2,100 first-year medical residents found that irregular sleep schedules can increase the risk of depression and negative mood. Those with variable wake-up times and sleep times were more likely to experience symptoms of depression.
A study by University of Granada researchers reveals that psychological variables contributed to increased anxiety and depression among pregnant women during the COVID-19 pandemic. Women who gave birth during the pandemic reported greater stress in delivery processes and lower quality of care received.
A study of over 7,100 veterans found that those with a combination of high depression, low social support, and low psychological resilience reported poor well-being. Higher psychological resilience mitigated the impact of depression on well-being.
The study analyzed tweets of 186 users taking antidepressant medication, revealing increased activity and positive emotions during treatment. Users posted longer messages with more interactions and fewer messages at night.
Researchers discover that a small group of neurons in the brain play a crucial role in depression. Chronic stress alters their function, leading to depressive behavior. Stimulation of these neurons reverses symptoms, suggesting a promising new approach to treating depression.
A study led by Johns Hopkins Bloomberg School of Public Health finds that nearly 60% of low-income, middle-aged African-American women with uncontrolled hypertension screened positive for depression. The researchers emphasize the need for routine screening and treatment for these women.
Long-COVID symptoms persist for over 12 weeks in many patients, causing health problems like cough, fatigue, and cognitive difficulties. Researchers explore potential pathways and propose strategies to manage symptoms using insights from studies of chronic fatigue syndrome, fibromyalgia, and depression.
Researchers developed a machine learning method to accurately diagnose patients with mixed symptoms, revealing that depression plays a greater role in psychosis than thought. The study highlights the need for better treatments and more accurate diagnostic methods.
A sequential approach to treating comorbid PTSD and major depressive disorder has shown promising results in a randomized control trial. The study found that combining Cognitive Processing Therapy (CPT) and Behavioral Activation Therapy (BA) led to meaningful reductions in PTSD and depression severity.
A new study found a reduced number of astrocytes in the brains of depressed adults compared to non-depressed individuals. The study suggests that targeting these cells may lead to improved treatment options for depression.
Researchers analyzed 94 million tweets to detect early signs of depression and suicidal thoughts during the pandemic. The study found a significant jump in depression levels at the start of the outbreak and a notable increase in users' social media time during lockdowns.
A new study examining sleep deprivation and frailty reveals that short sleep intensifies the impacts of frailty on depressive symptoms. Frail older adults who experienced worsening frailty and short sleep were more likely to develop higher levels of depression.
People with combined vision and hearing loss are nearly four times more likely to experience depression, while those with both issues suffer chronic anxiety. Researchers found a significant link between sensory loss and mental health problems in a study of over 23,000 adults.
A recent study found that minocycline, an antibiotic with anti-inflammatory properties, significantly improved depressive symptoms in patients with treatment-resistant depression and low-grade peripheral inflammation. The trial showed that patients with higher C-reactive protein levels responded better to minocycline treatment.
Research suggests that immune cells in the brain, microglia, contribute to negative mood experienced during inflammation and neurological diseases. Activating these cells can elicit a negative affective state in mice, highlighting their potential link to depression.
New research from McMaster University found that treating mothers with postpartum depression with cognitive behavioural therapy (CBT) results in healthy changes in the brains of their babies. The study also showed that these changes lead to improved infant behavior and reduced risk of emotional problems later in life.
A new study by Lund University researchers found that half of young people treated for severe obesity have neuropsychiatric problems, with two-thirds experiencing mental health issues. The study also revealed that symptoms of ADHD and autism are often misdiagnosed in teenagers with severe obesity.
Men's psychological well-being declined more than women during the second wave of the pandemic, with a significant drop in scores on the WHO-5 well-being index. The study suggests that uncertainty related to employment may play a role in this gender difference.
Scientists at UCSF have developed a personalized neuromodulation approach that targets individual patients' distinctive symptoms, providing relief from severe depression within minutes. The approach uses stereo-EEG to map brain regions and identify optimal stimulation sites.
Researchers developed a test to distinguish between forms of BDNF proteins, which can predict depression and bipolar disorder. The test uses serum mBDNF levels as a biomarker for diagnosis.
A study by Kayla Follmer and Jake Follmer found that low-grade forms of workplace mistreatment can amplify suicidal thoughts in employees with depression or bipolar disorder. The researchers surveyed 279 American adults and discovered that perceived mistreatment, job engagement, and suicidal ideation are linked.
Researchers found that persistently high insulin levels from mid-childhood are linked with a higher chance of developing psychosis in adulthood. In contrast, an increase in BMI around puberty was linked with a higher chance of depression in adulthood, particularly in girls.
Researchers found that certain metabolites can predict which patients are most likely to relapse into major depressive disorder. The study identified six metabolic pathways and specific lipids associated with the condition, suggesting a new approach for predicting vulnerability to depression recurrence.
A systematic review of 136 randomised controlled trials found that mindfulness reduces anxiety, depression and stress in most community settings, but with no significant benefit in over one in 20 trials. The findings suggest that individual results may vary depending on factors such as implementation, setting and target group.
Researchers combined psychiatric assessments with machine learning models to predict mental illness, improving disease course prediction and intervention timing. The algorithm assists decision-making and provides recommendations for targeted interventions.
A new study found that religious individuals employ cognitive reappraisal and coping self-efficacy, two psychological strategies linked to reduced anxiety and depression symptoms. The research suggests a convergence between science and religion in promoting well-being and resilience.
A recent study found that MBCT reduces feelings of self-inadequacy and improves self-reassurance in patients with depression. Individuals who showed improvements in self-reassurance were less likely to experience depressive relapse within 2 years after the intervention.
A study conducted by researchers from the Icahn School of Medicine at Mount Sinai found that repeated ketamine infusions significantly reduced symptom severity in individuals with chronic PTSD. The improvement was rapid and maintained for several weeks afterwards, suggesting this may be a promising treatment option for PTSD patients.
A new UC Berkeley study suggests that individuals with clinical anxiety and/or depression have difficulty making sound judgments when faced with changing circumstances. Emotionally resilient people, on the other hand, are better equipped to adapt to these changes by focusing on their past successes.
Researchers developed an AI that can detect the type of post-stroke depression (PSD) in patients, which is crucial for providing the right treatment. The study used a probabilistic artificial neural network to analyze data from 274 patients and found that early detection is key to improving functional recovery.
Researchers found a correlation between inflammatory molecules and depression severity, as well as a link between specific symptoms of menopause and depression. The study used data from the Dallas Heart Study to analyze the association between GlycA levels and depressive symptoms in adults.
A University of Gothenburg study reveals that male managers are more likely to hold negative attitudes toward depression, especially in senior positions. The research, which surveyed over 2,600 managers in Sweden, found that female managers had a significantly lower proportion of negative attitudes towards the mental disorder.
Researchers at the University of South Australia have made a breakthrough in treating post-stroke depression using high-frequency brain stimulation. The study found that large doses of repetitive transcranial magnetic stimulation (rTMS) significantly improved low moods by increasing brain activity.
A new national study by the University of Arkansas links increased social media use to developing depression in young adults. Young adults who used more than 300 minutes per day were 2.8 times as likely to become depressed within six months.
A review examines the bidirectional causal relationship between poverty and common mental illnesses, depression and anxiety. Interventions improving mental health or economic condition often positively affect those suffering from poverty or mental illness.
Depressed children and teenagers have a significantly higher risk of premature death, self-harm, and suffering from other diseases later in life. The study found that depression was associated with 66 out of 69 examined medical conditions, including sleep disorders, type 2 diabetes, and kidney disease.
Researchers at UC Davis have developed a non-hallucinogenic version of the psychedelic drug ibogaine, which retains therapeutic properties without its serious side effects. The new molecule, TBG, has shown promising positive effects in animal models of depression and addiction.