Articles tagged with Depression
A study published in JAMA Pediatrics found that maternal posttraumatic stress disorder (PTSD) is associated with an increased risk for child maltreatment. Mothers with comorbid PTSD and depression showed the highest levels of physically and psychologically abusive behaviors, highlighting the importance of measuring PTSD symptoms when a...
A Penn study finds that shutting off GABA neurons helps bullied mice overcome symptoms of depression and anxiety. The research suggests targeting GABA neurons as a new potential drug target to treat patients with depression and other mood disorders.
A new study published in Clinical Psychological Science found that divorce elevates the risk of future depressive episodes, but only for individuals who already have a history of depression. The study suggests that separation and divorce may exacerbate underlying risk rather than directly increasing rates of depression.
A recent study published in the Journal of Affective Disorders found that depressive symptoms are not as influenced by time of year or weather conditions as previously thought. Researchers analyzed data from over 800 participants and concluded that people may be exaggerating the impact of seasonal changes on their mood.
A Florida State University researcher is studying how estrogen and progesterone impact the antidepressant effects of ketamine, which has shown promise in treating depression. The goal is to find a safer treatment for men, who require higher doses, while minimizing side effects.
Researchers found that Xingnao Jieyu capsules upregulate synaptotagmin expression in rats with post-stroke depression, improving depression symptoms. The therapeutic effects of Xingnao Jieyu capsules are similar to those of fluoxetine.
A study by Boston College researchers found that grandparents and adult grandchildren have a measurable impact on each other's psychological well-being. An emotionally close relationship is associated with fewer symptoms of depression for both, while tangible support affects grandparents' psychological health.
A Canadian study found that women living in large urban areas have a higher risk of postpartum depression. The study analyzed data from 6421 women and found that urban residents had almost 10% reporting postpartum depression compared to 6% in rural areas.
A new Canadian study found that women living in large urban areas are at a significantly higher risk of postpartum depression after five to 14 months of giving birth. The researchers suggest differences in stress, social support and history of depression may contribute to this risk.
A University of Zurich study found online psychotherapy to be equally effective, and in some cases better than, face-to-face therapy in reducing depression. After treatment, 53-57% of patients showed significant improvement, with higher satisfaction rates for both groups.
A University of Utah study suggests that isoflurane, a surgical anesthetic, may provide an alternative to electroconvulsive therapy (ECT) for treating drug-resistant depression. The pilot study found significant reductions in symptoms of depression with both ECT and isoflurane treatments.
Researchers at Duke University Medical Center used pharmacometabolomics to analyze biochemical changes in people taking antidepressants, finding that those whose depression improved had distinct metabolic profiles. The study suggests that serotonin metabolism in the pineal gland may play a role in depression treatment outcomes.
Research suggests that vitamins and minerals, such as B and D, as well as omega-3 fatty acids, can improve mood and reduce fatigue. Supplementing with these nutrients may provide an alternative to psychiatric medicines for symptom relief.
Researchers at Michigan State University found a link between the prefrontal cortex and learning and behavioral deficits in mice with mental illness genes. This study suggests targeting specific brain-behavior mechanisms may alleviate cognitive and motivational symptoms.
Rates of severe depression fell significantly among older adults between 1998 and 2008, particularly among those aged 80-84, with late middle agers experiencing increased depression symptoms. Despite this trend, a significant percentage of the population continues to experience severe symptoms.
Researchers found decreased structural integrity of white matter tract connecting brain regions, but increased functional connection between them. This may contribute to abnormally high functional interactions among brain circuits associated with depression.
Research at the University of Liverpool found that individuals with depression tend to set broad, abstract personal goals, making it harder to visualize and achieve them. This can create a downward cycle of negative thoughts, further exacerbating depression.
A key brain structure that regulates emotions works differently in depressed preschoolers compared to their healthy peers, according to new research. The findings suggest the children's brains may be experiencing an exaggeration of a normal developmental response to emotions.
A new study has found that pre-existing insomnia symptoms in military service members prior to deployments may be at greater risk of developing posttraumatic stress disorder (PTSD), depression, and anxiety upon return. The study also identified short sleep duration as a significant risk factor for new-onset PTSD symptoms.
Researchers found SAD participants have misconceptions about sleep habits similar to those of insomniacs, leading to incorrect reports of sleep duration. Cognitive behavioral therapy for insomnia may be effective in treating seasonal affective disorder by addressing unhelpful beliefs about sleep.
A new study finds that involving community groups in depression care improves mental health outcomes among low-income patients. The community engagement approach, which included collaborative planning with diverse services programs, resulted in increased physical activity, lower hospitalizations, and improved stability in daily life.
Dr. Chrystyna Kouros' research project aims to understand barriers to treating depression in Hispanic youth, with a focus on ethnic differences in parental and child attributions about symptoms. The study seeks to fill an important gap in the literature by examining ethnicity as a moderating factor.
A pilot study found that vitamin D supplementation significantly lowered blood pressure and improved moods in women with type 2 diabetes and symptoms of depression. Vitamin D also helped the women lose weight. The study suggests that vitamin D supplementation may be a valuable treatment option for these women.
A synthetic compound has been discovered to enhance the effects of SSRIs, a commonly prescribed antidepressant. By blocking secondary 'vacuum cleaners' in the brain, the compound increases serotonin levels, offering new potential targets for treating depression. Researchers hope this discovery will lead to more effective treatments.
A study found high rates of burnout and depression among US anesthesiology residents, with nearly half considered at risk of burnout. The researchers also discovered that these conditions can affect the quality of patient care and increase medical errors.
Researchers at Loyola University Chicago will study whether vitamin D supplementation can improve mood and blood pressure in women with Type 2 diabetes and symptoms of depression. The six-month study aims to explore the potential benefits of vitamin D as an antidepressant therapy.
A randomized controlled study found that short-term therapy delivered by para-professionals significantly reduced mental health symptoms among rape survivors in the Democratic Republic of Congo. Cognitive processing therapy (CPT) was effective in reducing depression, anxiety, and post-traumatic stress disorder symptoms.
Research published in PLOS ONE found that mildly depressed individuals' ability to distinguish between high-fat and low-fat foods is affected by their mood. After watching a sad movie clip, participants with mild depression were unable to tell the difference between the two types of foods.
Case Western Reserve University researchers found that 52% of individuals with PTSD also report symptoms of depression. The study, published in the Journal of Traumatic Stress, analyzed data from 57 peer-reviewed studies and concluded that both genders diagnosed with PTSD equally suffer from depression.
International researchers found that all seven psychotherapeutic interventions have comparable effects on depressive symptoms, regardless of patient group or therapy type. The therapies worked equally well for individual and group therapy, as well as internet-based interactions.
A new study reveals that childhood bullying can significantly increase the likelihood of self-harm in late adolescence. The research found that those subjected to chronic bullying over several years at primary school were nearly five times more likely to engage in self-harm six to seven years later.
Researchers at Lund University have prevented early symptoms of Huntington's disease, depression, and anxiety in mice by deactivating the mutated huntingtin protein. This discovery is a major breakthrough and may lead to more accurate treatments for this debilitating disease.
A University of Illinois study found that good marriage can buffer the effects of a dad's depression on his young children. When fathers report high emotional intimacy in their marriage, their children benefit from improved father-child interaction.
A new study suggests that disturbed sleep in adolescents is associated with more symptoms of depression. However, perceived support and acceptance from parents and teachers appear to have a protective effect on sleep disruptions and depressive symptoms. Support from peers does not offer the same benefits.
Researchers found that individuals with untreated major depression have increased telomerase activity in immune cells, which may help fight back against disease progression. The study also suggests a potential protective role for telomerase in the hippocampus and reducing depressive symptoms with treatment.
A study of 4,296 people found that those with both conditions had smaller brain tissue volumes than those with neither. The study suggests that people with both migraine and depression may require different treatment strategies.
A clinical study demonstrates the durability of NeuroStar TMS Therapy in patients with Major Depressive Disorder (MDD) who have failed to respond to prior antidepressant medication. After acute treatment, patients maintained significant improvement and remission through 12 months, suggesting a long-term benefit of the therapy.
Hopkins researchers identify two genes, TTC9B and HP1BP3, that can predict postpartum depression with 85 percent certainty in pregnant women. The study's findings could lead to early intervention and treatment options for the condition.
A new study has identified risk factors for depression among COPD patients, including female patients and those experiencing significant shortness of breath. The study found that physical activity was a protective factor against depression, with patients who had higher levels of physical activity less prone to developing depression.
Researchers found ketamine to be effective in treating treatment-resistant depression within 24 hours, with a response rate of 63.8% compared to 28% in the placebo group. The antidepressant benefits were durable after seven days, making ketamine a promising new treatment option for patients with severe and refractory forms of depression.
A survey of 161 military personnel found that those with multiple head injuries face a significantly higher risk of suicidal thoughts and behaviors. The study's lead author says that knowing this association can provide valuable information for professionals treating wounded combat servicemen and women to help manage the risk of suicide.
Researchers found that depressed individuals express personal goals in vague terms, such as 'to be happy,' rather than specific objectives like improving a running time. This reduced specificity may be linked to the motivational deficits seen in depression, and could inform more effective psychotherapeutic approaches.
Researchers found that genes controlling circadian clock rhythms are profoundly altered in the brains of people with severe depression, suggesting a physical basis for many symptoms. The study provides clues for potential new classes of compounds to rapidly treat depression by resetting abnormal clock genes.
New guidelines from the Canadian Task Force on Preventive Health Care recommend against routine screening for depression in adults without apparent symptoms. The recommendations are based on a lack of high-quality evidence on the benefits and harms of screening. Clinicians should be alert to the possibility of depression in patients wi...
The Lancet Series on bipolar disorder offers a comprehensive overview of the condition, including its genetic basis, diagnostic challenges, and treatment limitations. The series highlights the need for more accurate diagnosis and personalized treatments, with neuroimaging research potentially transforming bipolar diagnosis.
Researchers found that vagus nerve stimulation brings about changes in brain metabolism weeks or months before patients begin to feel better. The treatment was able to improve symptoms of depression in 9 out of 13 participants, with significant changes in brain metabolism occurring far in advance of any improvement in mood.
A new study found that adults with depression and certain antidepressant medications are more likely to develop Clostridium difficile infections, a serious and costly hospital-associated infection. Individuals with major depression were 36% more likely to develop the infection than those without depression.
Researchers identified a key protein responsible for stress hormones' detrimental effect on brain cells. A new compound was found to block this effect, increasing the number of new brain cells in a potential new avenue for drug discovery.
A recent study has found a significant link between certain antidepressants and an increased risk of Clostridium difficile infection. People with major depression were 36% more likely to develop CDI, while the use of mirtazapine and fluoxetine doubled the risk. Researchers stress that the exact cause of this association is unknown.
Researchers have developed a new, more precise form of electroconvulsive therapy (ECT) called FEAST, which shows promising results in reducing depressive symptoms with minimal adverse cognitive effects. In a feasibility study, patients experienced significant improvements after just 10 sessions over four weeks.
A large randomised controlled trial found that exercise had no effect on reducing depression among frail elderly care home residents. Despite being well-received by residents and staff, the intervention failed to improve mental health or quality of life.
A new study found that only 38.4% of adults with clinician-identified depression met the 12-month criteria for depression. Many participants used prescription psychiatric medication despite not meeting the criteria, highlighting the need for improved diagnosis and treatment targeting in community settings.
Research reveals that strained relationships with spouses and low-quality social interactions significantly increase the risk of major depression. In contrast, individuals without a spouse are at no increased risk, highlighting the importance of relationship quality in mental health.
Early child adversity can lead to chronic physical and mental disability, as well as increase the risk of smoking, substance abuse, obesity, cardiovascular disease, depression, and attempted suicide. Effective interventions, such as maternal depression treatment and economic support, can reverse or attenuate these effects.
Flies develop depression-like symptoms in response to uncontrollable stress, slowing down and taking more frequent rests. The study offers insights into the biological basis of depression and presents a potential method for testing antidepressant drugs.
A new study reveals that a particular style of thinking can be contagious and increase symptoms of depression. College freshmen who were assigned to roommates with high levels of cognitive vulnerability showed an increase in their own vulnerability and depressive symptoms six months later.
A public-private partnership (PPP) successfully addressed the mental health needs of people in post-conflict northern Uganda, establishing five psycho-trauma centers and increasing clinic attendance from 300 to over 3,000. The most common diagnoses were depression, PTSD, epilepsy, and substance use disorders.
A study found that electroconvulsive therapy (ECT) can improve the quality of life for severely depressed patients who go into remission. However, patients may experience challenges with social function and emotional role after treatment.
Researchers at Bonn University Hospital have achieved remarkable results using deep brain stimulation to treat treatment-resistant major depression. In six out of seven patients, symptoms improved considerably and rapidly, with significant improvements observed in anxiety, despondence, listlessness, and joylessness.
A recent CWRU study found that mothers with postpartum depression prefer online interventions for anonymous access to professional advice. The study also highlights the need for accessible resources to help new mothers cope with depression, which affects up to 15% of new mothers.