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Study finds non-hallucinogenic psilocybin neural receptor

A Dartmouth study identifies a novel target for using psilocybin to treat depression and anxiety without hallucinations. The serotonin 1B receptor is found to promote the therapeutic benefits of psilocybin, providing a potential new approach for developing safer and more cost-efficient medications.

SourceDartmouth College·JournalMolecular Psychiatry·TypeExperimental study·DateJan 12, 2026

Chongqing Medical University team: dual-branch graph attention network enables personalized prediction of ECT efficacy in adolescent depression

A team from Chongqing Medical University developed a model that integrates sMRI and fMRI data to predict treatment responders, achieving high accuracy rates. The dual-branch graph attention network (DBGAN) captures coordinated brain changes linked to emotion regulation and memory processing.

SourceKeAi Communications Co., Ltd.·JournalMeta-Radiology·TypeImaging analysis·DateJan 11, 2026

Schizophrenia and osteoporosis share 195 genetic loci, highlighting unexpected biological bridges between brain and bone

A comprehensive genetic investigation by Dr. Feng Liu and collaborators identifies shared genetic loci between schizophrenia and osteoporosis, suggesting overlapping biological pathways. The study found that psychiatric patients face elevated fracture risks due to these molecular connections.

SourceGenomic Press·JournalGenomic Psychiatry·TypeData/statistical analysis·DateJan 6, 2026

Schizophrenia-linked genetic variant renders key brain receptor completely unresponsive to both natural and therapeutic compounds

Researchers at Flinders University discover a genetic mutation that silences a brain receptor, rendering it unresponsive to both natural trace amines and clinical drug candidates. The C182F variant eliminates receptor signaling and reduces cell surface expression, with profound implications for emerging psychiatric treatments.

SourceGenomic Press·JournalGenomic Psychiatry·TypeExperimental study·DateJan 6, 2026

The untold story of life with Prader-Willi syndrome - according to the siblings who live it

A new study reveals the emotional challenges faced by siblings of people with Prader-Willi syndrome, including feelings of stress, loneliness, and sadness. Siblings often take on extra responsibilities at home and struggle to cope with their brother or sister's behavior and hunger.

SourceUniversity of East Anglia·JournalJournal of Applied Research in Intellectual Disabilities·TypeSystematic review·DateJan 6, 2026

ACC/AHA issue new guideline on managing congenital heart disease in adults

Adults born with heart defects are at increased risk of cardiac complications as they age. The new guideline provides recommendations for monitoring, counseling, and treating Congenital Heart Disease (CHD), including mental health assessment and physical activity guidance. It also emphasizes the importance of access to ongoing speciali...

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateDec 18, 2025

Journal highlights need to transform girls’ mental health care

A special issue of Child and Adolescent Psychiatric Clinics of North America seeks to transform how clinicians, educators, and policymakers think about girls' mental health by focusing on systems that support or fail to support them. The issue explores intersectionality, trauma-informed approaches, and the impact of social media on bod...

SourceUniversity of California - Riverside·JournalChild and Adolescent Psychiatric Clinics of North America·TypeObservational study·DateDec 18, 2025

How does grandparental care affect children’s health?

Regular grandparental care can ease the pressures on parents but may have negative impacts on children's health, with some children showing poorer general health in studies of over 11,000 kids. Grandparental care also benefits parents' satisfaction rates, particularly mothers and fathers.

SourceWiley·JournalHealth Economics·DateDec 17, 2025

Jeonbuk National University study shows positive parenting can protect adolescents against self-harm

A recent study by Jeonbuk National University researchers found that positive parenting styles can significantly reduce the risk of self-harm in adolescents. The study analyzed data from over 3,900 participants and identified three distinct parenting styles: negative, average, and positive, with positive parenting being the most protec...

SourceJeonbuk National University, Sustainable Strategy team, Planning and Coordination Division·JournalActa Psychologica·TypeData/statistical analysis·DateDec 16, 2025

Tech savvy users have most digital concerns

A new study found that highly educated, Western European millennials have the most digital concerns, with individuals having higher levels of digital literacy being the most affected. The research also found that people's perceptions of digital harm are heightened by their level of digital exposure and knowledge.

SourceUniversity College London·JournalInformation Communication & Society·TypeData/statistical analysis·DateDec 14, 2025

AI chatbots could help reduce mental health stigma

A new study suggests that AI chatbots like ChatGPT can help reduce mental health stigma by making people feel more comfortable seeking support. The research found that believing the tool is effective plays a key role in reducing concerns about external judgment and increasing its perceived effectiveness.

SourceEdith Cowan University·JournalBehavioral Sciences·TypeSurvey·DateDec 14, 2025

Sweeping study shows similar genetic factors underlie multiple psychiatric disorders

A recent study has identified five categories of psychiatric disorders that share similar genetic factors, including compulsive features, internalizing conditions, substance use disorders, neurodevelopmental conditions, and a category combining bipolar disorder and schizophrenia. The research suggests that these shared genetic factors ...

SourceUniversity of Colorado at Boulder·JournalNature·TypeData/statistical analysis·DateDec 11, 2025

How maternal distress affects neurological development in children: New study sheds light

A new study found that maternal psychological distress experienced at 1 year postpartum has a stronger association with neurodevelopmental delay in toddlers compared to prenatal distress. The researchers also discovered that experiencing distress during both pregnancy and postpartum periods further amplifies the risk of delays.

SourceUniversity of Toyama·JournalJAMA Network Open·TypeObservational study·DateDec 8, 2025

Depression more common among women with gynecological disorders

A new study from the University of Southern Denmark reveals that depression is significantly more common among women with gynaecological disorders—both before and after receiving a diagnosis. The study highlights the need for earlier detection and a more integrated approach between somatic and psychiatric care.

SourceUniversity of Southern Denmark Faculty of Health Sciences·JournalPsychological Medicine·TypeData/statistical analysis·DateDec 4, 2025

FAU study finds connection between poor mental health and dark web use

A new FAU study reveals significant mental health differences between dark web users and surface web users, with dark web users reporting substantially higher levels of depressive symptoms and paranoid thoughts. The study also found substantial differences in suicidal thoughts, non-suicidal self-injury, and digital self-harm.

SourceFlorida Atlantic University·JournalCyberpsychology Behavior and Social Networking·TypeSurvey·DateDec 3, 2025

Mental health conditions may heighten liver cancer risk in veterans due to increased hepatitis C, UCLA study finds

A recent study by UCLA Health investigators found that mental health conditions significantly raise the likelihood of developing liver cancer among US veterans living with cirrhosis and hepatitis C. The study suggests that these disorders limit access to hepatitis C care, reducing the chance of a cure.

SourceUniversity of California - Los Angeles Health Sciences·JournalClinical Gastroenterology and Hepatology·DateDec 3, 2025

December 2025 issues of APA Journals feature new research on borderline personality disorder, depression, trauma interventions in schools, and more

The December issues of The American Journal of Psychiatry and Psychiatric Services feature updates on substance use disorders, depression, and borderline personality disorder treatment. New research on trauma interventions in schools aims to improve mental health support for students.

SourceAmerican Psychiatric Association·JournalAmerican Journal of Psychiatry·DateDec 2, 2025

Long-term antidepressant use surges in Australia, sparking warnings of overprescribing

A new study found that long-term antidepressant use has increased by nearly 20% among young people aged 10-24, raising concerns about potential overprescribing. The study also found no meaningful improvement in efforts to wean patients off antidepressants, highlighting the need for a stronger framework for safely tapering medications.

SourceUniversity of South Australia·JournalPharmacoepidemiology and Drug Safety·TypeData/statistical analysis·DateDec 2, 2025