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People without jobs or secure housing have worse outcomes when treated for depression

A recent study published in JAMA Psychiatry has found that individuals without jobs or stable housing experience worse depression symptoms when treated with therapy or antidepressants. The researchers analyzed data from nine studies involving over 4,800 participants and discovered that unemployed patients had 28% poorer outcomes compar...

SourceUniversity College London·JournalJAMA Psychiatry·TypeMeta-analysis·DateMar 9, 2022

Psilocybin treatment for major depression effective for up to a year for most patients, study shows

A study by Johns Hopkins Medicine researchers found that psilocybin-assisted therapy can lead to significant and durable improvements in depression, with effects lasting at least a year for most patients. The treatment was shown to produce large decreases in depression severity and stable rates of response throughout the follow-up period.

SourceJohns Hopkins Medicine·JournalJournal of Psychopharmacology·DateFeb 15, 2022

Where mental health help is scarce, telehealth makes a big difference

A randomized study of over 1,000 people with PTSD and/or bipolar disorder shows that telehealth and integrated care models can improve treatment engagement and outcomes. Patients who received guidance from local clinic team members and in-person follow-up with nurses or social workers had better results.

SourceMichigan Medicine - University of Michigan·JournalJournal of General Internal Medicine·TypeRandomized controlled/clinical trial·DateFeb 7, 2022

Prolonged exposure or cognitive processing therapy?

A landmark VA study found that prolonged exposure was statistically more effective than cognitive processing therapy in easing PTSD symptoms, with most Veterans showing meaningful improvement from both treatments. The researchers recommended shared decision-making between clinicians and patients to select their preferred treatment.

SourceVeterans Affairs Research Communications·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateJan 19, 2022

Computer-, smartphone-based treatments effective at reducing symptoms of depression

A meta-analysis of 83 studies found that digital interventions improved depression symptoms over control conditions, but the effect was not as strong as face-to-face psychotherapy. Digital treatments with human components were most effective in reducing symptoms, particularly when accompanied by human guidance.

SourceAmerican Psychological Association·JournalPsychological Bulletin·TypeMeta-analysis·DateDec 13, 2021

Talk therapy by US psychiatrists declined by half since 1990s

A study found that the percentage of psychiatrist visits involving psychotherapy dropped to 21.6% between 1996 and 2016, with rural and Black/Hispanic patients experiencing significant declines. The shift towards medication management is attributed to economic factors and a national shortage in psychiatric services.

SourceColumbia University Irving Medical Center·JournalAmerican Journal of Psychiatry·TypeMeta-analysis·DateDec 8, 2021

Computer training to reduce trauma symptoms

Researchers from Ruhr-University Bochum found that computerised training can reduce PTSD symptoms by helping patients reappraise trauma memories. Patients who underwent the 'Cognitive Bias Modification-Appraisal' training showed fewer trauma-relevant symptoms and lower stress hormone levels compared to those in a control group.

SourceRuhr-University Bochum·JournalPsychotherapy and Psychosomatics·DateFeb 25, 2021

Cognitive behavior therapy tops other psychotherapies in reducing inflammation

A review of 56 randomized clinical trials found that cognitive behavior therapy is superior to other psychotherapies in reducing inflammation and boosting the immune system. CBT was most effective in reducing pro-inflammatory cytokines, which are associated with chronic diseases such as heart disease, cancer, and Alzheimer's disease.

Unique patterns of brain activity predict treatment responses in patients with PTSD

A neuroimaging study identified unique brain activity patterns that predict poorer responses to talk therapy in patients with PTSD. Patients with impaired verbal memory and VAN function had poorer outcomes after psychotherapy, while those with intact verbal memory or normal VAN function were more responsive.

SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience Translational Medicine·DateApr 3, 2019

MDMA opens door for PTSD sufferers

The MDMA-assisted psychotherapy trial at UConn Health will specifically recruit people from communities of color with PTSD, focusing on experiences of racial violence and discrimination. The treatment has shown promise in reducing symptoms and allowing patients to process their trauma into something stronger.

Brain scans may help clinicians choose talk therapy or medication treatment for depression

Researchers found that specific brain scan patterns can identify which treatment is most effective for individual patients with depression. Patients with positive connectivity in certain brain regions were more likely to achieve remission with cognitive behavioral therapy, while those with negative connectivity were more likely to resp...

SourceEmory Health Sciences·JournalAmerican Journal of Psychiatry·DateMar 24, 2017

Brain scans could help predict response to psychotherapy for anxiety and depression

Research found promising initial evidence that specific neuroimaging markers can help predict the response to psychotherapy in patients with depression or anxiety. Neuroimaging markers such as activity in the amygdala, anterior insula, and anterior cingulate cortex may indicate which patients are more likely to benefit from psychotherapy.

SourceWolters Kluwer Health·JournalHarvard Review of Psychiatry·DateNov 10, 2016

Clinical trial examines treatment of complicated grief

A randomized clinical trial found that psychotherapy for complicated grief is efficacious and adding antidepressant citalopram improves outcomes for those with co-occurring depressive symptoms. The study's results support using antidepressants in conjunction with therapy for relief of co-occurring symptoms.

SourceJAMA Network·JournalJAMA Psychiatry·DateJun 8, 2016

Racial and ethnic differences found in psychiatric diagnoses and treatment, according to researchers

Non-Hispanic blacks are almost twice as likely to be diagnosed with schizophrenia as non-Hispanic whites, but they're significantly less likely to receive medication for treatment. The study found that racial-ethnic differences in diagnosis and treatment of psychiatric conditions were significant across 11 private healthcare delivery s...

SourceGeorgia State University·JournalPsychiatric Services·DateMay 17, 2016

Very little evidence for cutting out certain carbs to ease irritable bowel

A review of the available data concludes that there is very little evidence to recommend a low FODMAP diet as an effective treatment for irritable bowel syndrome symptoms. While some studies suggest potential benefits, such as changes in gut bacteria profiles, more research is needed to establish its efficacy and long-term effects.

SourceBMJ Group·JournalDrug and Therapeutics Bulletin·DateAug 6, 2015

New therapy for personality disorders proven more effective than other major treatments

A large-scale randomized control trial shows Schema Therapy to be significantly more effective than Clarification-Oriented Psychotherapy and treatment as usual in treating a range of personality disorders. The therapy resulted in higher recovery rates, greater declines in depression, and lower dropout rates.

SourceInternational Society of Schema Therapy·JournalAmerican Journal of Psychiatry·DateFeb 10, 2014