Researchers at NIAID have determined the entire genetic sequence of molluscum contagiosum virus (MCV), which causes persistent and sometimes disfiguring skin lesions in HIV-infected individuals. The complete DNA sequence will enable testing of drugs against MCV genes and studying how the virus evades immune responses.
Researchers at Johns Hopkins University have made a surprising discovery about the movement of proteins within the Golgi apparatus. The enzymes, which are crucial for various cellular processes, were found to be mysteriously retained in the organelle despite their rapid movement, contradicting long-held assumptions about their function.
Researchers found a mutant gene in C. elegans that doubles adult lifespan when mutated, suggesting its role in regulating aging. The gene encodes a PI(3)K enzyme, which may trigger a biochemical program leading to decreased aging and senescence.
A new study by the NHLBI shows that bone marrow transplantation can provide a cure for young patients with sickle cell disease who have a matched sibling. The procedure has an overall survival rate of 90% and successfully transplanted 73% of participants, free from sickle cell disease.
Researchers have discovered complex organic molecules and mineralogical evidence of past life in the Martian meteorite ALH84001. The study suggests that these findings could be indicative of primitive life on early Mars.