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Science News Archive 1997 - Page 10


Page 10 of 29

Common Drug-Capsule Coating Not As Inert As Previously Thought

A recent study at the University of Illinois found that polyethylene glycol (PEG) coating can undergo attractive interactions with proteins, changing its configuration and potentially increasing biocompatibility. The discovery has significant implications for biomedical applications, such as implants and artificial scaffolds.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the National Academy of Sciences·DateOct 3, 1997

Scientists Find New Trigger For Nerve Cell Death

Researchers found that potassium ions play a critical role in triggering programmed cell death or apoptosis in nerve cells. By blocking potassium channels, they may be able to prevent nerve cell death and reduce brain damage in patients with stroke, spinal cord injuries, or neurodegenerative disorders.

SourceWashU Medicine·JournalScience·DateOct 3, 1997

Stress Of Caring For Older And Ill Relatives Can Lead To Serious Depression Or Resentment For Caregivers

A new model developed by psychologists at the University of Georgia can predict how caregivers will suffer from depression or resentment based on their past relationship with the spouse they care for. The research, supported by grants from the National Cancer Institute and the National Institute of Mental Health, may help family caregi...

SourceUniversity of Georgia·JournalHealth Psychology·DateOct 2, 1997

OHSU Researchers Discover Host Site, Activation Mechanism For Virus That Causes Birth Defects And Deaths Following Transplant

Researchers Cecilia Soderberg-Naucler and Jay Nelson identified the host site where human cytomegalovirus (HCMV) resides and developed an activation mechanism in specific white blood cells. This breakthrough could lead to more effective treatments for HCMV-related complications, including birth defects and transplant deaths.

"Male-Stuffing" Conserves Food In Wasp Nests

Researchers at Cornell University discovered a unique behavior in paper wasps called 'male-stuffing,' where females aggressively force males into empty nest cells to limit their food consumption. This behavior may maximize worker wasps' inclusive fitness and contribute to the colony's fitness.

SourceCornell University·JournalNature·DateOct 1, 1997

Two-Pronged Attack On Immune System Cells Engineered By HIV Gene vpr: Effects Markedly Reversed By Antisteroid Compound RU-486

Researchers found that HIV gene vpr blocks cytokine production in infected cells, preventing immune activation. Vpr also prevents apoptosis in infected cells but induces apoptosis in neighboring immune cells, making it harder for the body to defend against the infection. The antisteroid compound RU-486 reversed many of these effects.

Modified Catalyst Simplifies Manufacture Of Myriad Goods

Scientists have discovered a new catalyst that enables the production of alpha-olefins at lower temperatures and pressures, resulting in higher-purity products. The modified metallocene catalyst simplifies the manufacturing process for plastics and other consumer goods, potentially reducing costs and improving safety.

SourceUniversity of Rochester·JournalJournal of the American Chemical Society·DateOct 1, 1997

Scientists Develop Powerful Tool For Studying TB

Researchers have created an efficient method to study Mycobacterium tuberculosis (TB) using transposon mutagenesis, allowing them to examine the effect of individual gene mutations on the bacteria's ability to grow or cause disease. This breakthrough enables the development of new drug targets and potential vaccine candidates.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalProceedings of the National Academy of Sciences·DateSep 29, 1997

New Discovery May Offer Protection Against Stroke

A new study suggests that inhibiting poly(ADP-ribose) polymerase (PARP) enzyme may protect nerve cells from energy loss and prevent irreversible damage after a stroke. The research, published in Nature Medicine, found that genetically modified mice without the PARP gene experienced reduced brain damage compared to unaltered mice.

SourceJohns Hopkins Medicine·JournalNature Medicine·DateSep 29, 1997

Novel Death-Receptor Gene Identified: KILLER/DR5 Triggers Cancer Cell Death After Chemotherapy Or Radiation

Researchers at the University of Pennsylvania School of Medicine have identified a novel death-receptor gene called KILLER/DR5 that responds to chemotherapy and radiation by killing cancer cells. The discovery provides new insights into how cancer cells are killed after treatment, with potential implications for improving cancer therapy.