Eukarion's antibody lipidation technology successfully blocks HIV-1 viral replication in human lymphocytic cells by targeting the Tat protein. The modified anti-Tat antibody is effective against laboratory and patient-strain viruses, offering new potential for cell-specific AIDS immunotherapies.
Research sheds light on climate change by showing fish in Antarctica and Arctic independently evolved similar antifreeze glycoproteins, linked to environmental adaptation. The genes arose around 5-14 million years ago, providing new evidence for the Southern Ocean's freezing timeline.
Protein binding events control many biological processes; removing water from binding sites provides energy that drives reactions. Duke researchers used a supersensitive instrument to measure minute temperature changes in normal and heavy water to separate protein-water interactions from ligand-water interactions.
Researchers discovered a way to disrupt the aggregation of proteins that form poisonous plaque deposits in Alzheimer's patients. By synthesizing specific inhibitor molecules, they successfully blocked the toxicity of beta amyloid proteins, potentially leading to new treatments for the devastating disease.
Researchers at the University of Pittsburgh Cancer Institute have found that vitamin D significantly reduces prostate cancer growth in rats. Tumors in treated rats were 88% smaller than those in control rats, and lung metastases were also reduced.
Researchers at the University of Delaware have developed a new theory on how chemical additives alter the growth rate of silicon and silicon-germanium alloys. By understanding this mechanism, they hope to improve the control of electronic properties in films grown from chemical vapors at low temperatures.
Researchers have identified a mechanism to trap key industrial metals such as nickel, copper and zinc in soils, reducing their mobility. This discovery could lead to more effective cleanup techniques using traditional methods.
A new screening procedure developed at Cornell University Medical College reliably identified persons with personality pathology using a self-administered true-false questionnaire. The test was then confirmed or discounted through a follow-up interview with a professional clinician.
Researchers at University at Buffalo demonstrate strongest evidence yet for reentrant superconductivity, a phenomenon where magnetic fields enhance superconductivity rather than destroy it. The findings have potential practical applications in energy storage and magnetic resonance imaging.
University of Delaware researchers use a 'bicyclic lactone' to synthesize five unique compounds derived from red sea algae, making them easier to access for potential pharmaceutical uses. The process allows for efficient synthesis in large quantities, paving the way for further research into the compounds' biological activity.
Researchers found that genetic variations in enzymes metabolizing drugs contribute to cancer risk, particularly head and neck cancer. Individuals with certain enzyme genotypes or histories of environmental exposures are at increased risk for cancer.
Researchers from Boston University developed network measurement techniques that enable Net.Medic to identify and fix internet performance problems. The software is designed to improve the effectiveness of the internet for millions of users worldwide.