Researchers discovered a simple mechanism of aging in yeast cells, where extrachromosomal ribosomal DNA (ERCs) replicates until the cell dies. ERCs' accumulation causes enlargement and fragmentation of the nucleolus, leading to cell death, suggesting a potential target for intervening aging processes.
Researchers found that making optimal use of backup agreements between catalogers and manufacturers can increase net cash by almost 50%. The strategy, tested on a multibillion-dollar retail giant, is applicable to various industries with seasonal demand fluctuations.
Researchers have identified a new molecular switch that triggers mismatch repair in cells, which can prevent colon cancer. The discovery provides a foundation to specifically target anticancer drugs to this gene.