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Science News for November 19, 1997


Genetic Variation For Enzyme In Lung May Point To Cancer Susceptibility Gene, Mechanisms That May Cause Cancer

A recent study suggests that a human gene variation affecting lung enzyme production may be associated with reduced susceptibility to lung cancer. The study found that approximately 8% of the population has the 'protective' gene form, which reduces by about 54% the risk of developing lung cancer among smokers.

SourceNIH/National Institute of Environmental Health Sciences·JournalCancer Research·DateNov 19, 1997

Grapefruit Juice Used To Squeeze More Out Of Medications

Researchers isolated two substances in grapefruit, furanocoumarins, that increase drug absorption by inhibiting an enzyme called CYP3A4. This discovery could lead to improved oral medications and increased reliability of drugs.

SourceUniversity of Michigan·JournalDrug Metabolism and Disposition·DateNov 19, 1997
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