Vanderbilt University Medical Center researchers found that a 'transporter molecule' called P-glyco protein may prevent protease inhibitors from reaching the virus, raising hope for boosting treatment effectiveness and reducing costs. The discovery could provide new strategies for treating HIV by targeting the protein's action.
Scientists have determined the 3D molecular structure of HIV's nucleocapsid protein, which recognizes and binds to viral RNA. This discovery may lead to the development of highly specific anti-AIDS drugs that can prevent HIV spread and be safe for patients.
The research reveals the structure of T7 DNA polymerase, a protein crucial for DNA replication, showcasing its high accuracy and speed. The study provides insights into how this enzyme achieves its accuracy and could guide the development of better reagents for DNA sequencing.
Researchers from Vertex Pharmaceuticals have solved the three-dimensional atomic structure of the hepatitis C virus NS3 helicase enzyme, an enzyme critical to viral replication. The achievement provides valuable insights into the mechanism of helicase enzymes and offers opportunities for accelerating antiviral drug development.
The Institute of Food Technologists (IFT) Foundation has received a $60,000 grant from The Gerber Foundation to administer fellowships to graduate students focusing on pediatric nutrition. This grant will support tuition assistance and recognition for successful fellowship recipients.
Researchers have isolated a bacterial protein that allows Helicobacter pylori to attach to the gastric lining, a key step in developing a vaccine against peptic ulcers and gastric cancer. The discovery of BabA protein, found on the surface of H. pylori, could lead to an effective, cheap vaccine that boosts immunity after every exposure.