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Science News for August 3, 1999


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Scientists discover second gene for disorder described by Darwin

Researchers have found another aberrant gene on chromosome 2 that produces identical symptoms to the X-chromosome gene discovered earlier. The discovery improves genetic diagnosis prospects and may help in developing future therapies for hypohidrotic ectodermal dysplasia.

SourceNIH/National Institute of Dental and Craniofacial Research·JournalNature Genetics·DateAug 3, 1999

Factor for acquiring skin barrier function identified

Scientists at the University of Chicago Medical Center have discovered a key gene that enables skin to acquire its barrier function, which is crucial for preventing dehydration and infections in premature babies. The study uses genetically engineered mice with a mutated Klf4 gene to demonstrate the importance of this factor.

SourceUniversity of Chicago Medical Center·JournalNature Genetics·DateAug 3, 1999