Researchers found HIV's impact on T-cell production and its role in the immune system. The study involved measuring daily rates of new T-cell production in HIV-negative adults and those with suppressed virus, revealing a surprising increase in new cell production responsible for increased T-cell counts.
A portfolio optimization model (POM) developed in 1989 helps Chicago's Peoples Energy utilities balance costs by reserving natural gas supply, transportation, and storage. The model generates significant annual cost savings of $50 million since 1995, improving efficiency and decision-making.
Researchers have successfully developed a novel therapy that uses a fusion protein to selectively kill HIV-infected cells by triggering a chain of suicidal events. This approach has potential applications in treating other infectious diseases such as hepatitis C and malaria, and may also be used to target cancer cells.
Researchers have developed a new approach to solve multi-objective groundwater remediation problems, allowing decision-makers to weigh conflicting objectives like risk and cost. The Niched Pareto procedure will enable the creation of tradeoff curves to guide decision-making towards optimal solutions.
The National Institute on Alcoholism and Alcohol Abuse has awarded a $7 million grant to Wake Forest University Baptist Medical Center to study the causes of alcohol addiction. The studies will provide insights into brain processes that lead to alcoholism, with a focus on understanding the fundamental actions of alcohol on the brain.
A UK study found that decreasing food intake can help ward off age-related brain disorders such as Alzheimer's disease and Parkinson's disease. The research team led by Mark Mattson discovered that eating less made nerve cells in the brain more resistant to deterioration and death.
A new study reveals that alpha V beta 5-integrins on cell surfaces facilitate the entry of genetically engineered AAV viruses into cells, allowing for efficient gene delivery. This understanding can lead to improved gene therapy methods and enhanced chances of successful treatment outcomes.
Patients are willing to disclose behavior that puts them at risk for conditions ranging from HIV to domestic violence, regardless of the method used. The study's findings suggest that doctors can initiate discussions about sensitive subjects without worrying about patient willingness.
Researchers have successfully used gene therapy to partially correct protein deficiency responsible for hemophilia B in dogs, suggesting its potential for human treatment. The corrected genes produced blood clotting protein factor IX steadily more than a year and a half after treatment.