Researchers created genetically engineered mice with pathological characteristics of Alzheimer's disease, providing a new model for studying the disease. The mice exhibit amyloid deposits similar to those found in human patients, and further elevation of beta-amyloid accelerates the age of onset of pathological changes.
SourceCase Western Reserve University·JournalNature Neuroscience·DateJul 20, 1999
The Pacific Northwest National Laboratory has won six spots on the 1998 R&D 100 list, recognized for their innovative technologies that have transformed industries such as personal heating, fuel cell-powered cars and environmental conservation. The researchers' advancements include tiny personal heating systems, advanced chemical m...
SourceDOE/Pacific Northwest National Laboratory·DateJul 20, 1999
Penn State researchers developed a neural network-based model to predict tire stress on roads, providing engineers with improved capabilities for designing better tires and roads. The software can accurately predict outcomes even without training data, using precisely measured contact-stress distribution patterns.
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A decade-long primate study on diet and aging will be extended with a $6.75 million NIH grant, exploring mechanisms of aging in rhesus macaques. The research aims to answer whether calorie restriction can slow or prevent aging, building on existing studies in rodents.
A research team suggests that electronic charge transfer in DNA occurs through temporary distortions in its structure, creating a 'polaron' that carries the charge. This process can help scientists understand DNA damage and repair mechanisms, leading to potential applications in diagnostic techniques and micromachines.
SourceGeorgia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJul 20, 1999
A mathematical model of H.pylori bacteria and their human hosts reveals the key role played by adherent bacteria in colonization, as well as the dynamic relationship between host response and bacterial persistence. The model sheds light on the complex interactions between the bacteria and human immune system.
SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateJul 20, 1999
A team of researchers at Washington University School of Medicine has been awarded a grant to develop new treatments for spinal cord injuries. They plan to use embryonic stem cells to replace damaged tissue and restore lost functions, with the long-term goal of enabling patients to regain bladder and bowel control and potentially walk ...
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A new study found that workplace cancer control programs can improve the nutritional environment and eating habits of employees. The Working Well Trial showed significant improvements in healthy food options, fruit and vegetable access, and reduced fat and added sugars.
SourceCenter for Advancing Health·JournalHealth Education & Behavior·DateJul 20, 1999
A study of 729 low-income urban older patients found limited confidence in physical exercise abilities due to environmental and physiological barriers. Encouragement from family, friends, or doctors increased confidence in exercising, while fear of crime actually boosted it.
SourceCenter for Advancing Health·JournalHealth Education & Behavior·DateJul 20, 1999
Phyllis I. Hanson, a researcher at Washington University School of Medicine, has been awarded a Keck Foundation grant to study the molecular machinery that neurons use to communicate. Her work may one day suggest treatments for neuromuscular and psychiatric disorders resulting from faulty communication between neurons.