A UNC-CH study explains that variations in Earth's orbit over tens of thousands of years account for the timing of ice ages, providing a more complex understanding of long-term climate change. This new research confirms a theory from the 1920s and sheds light on predicting future global climate change.
Recent findings in cystic fibrosis (CF) suggest that gene mutations can cause unexpected effects, leading to distinct conditions with clinical similarities to CF. Minor mutations may result in partial disease manifestations, challenging traditional notions of genetic screening and diagnosis.
National Jewish researchers identified the specific peptide, ND1, on MHC molecules that controls positive selection of T cells. This discovery helps expand understanding of how the immune system develops and may lead to new treatments for cancer and autoimmune diseases.
Neurobiologists at Duke University Medical Center have captured the first detailed images of the living brain in action, revealing how it recognizes specific odor molecules. The imaging technique can provide new insights into the machinery of learning and help decipher the brain's internal 'language' of smell.
Vanderbilt's Program in Human Genetics will play a key role in identifying genes involved in common diseases, with initial focus on depression and sepsis. The program will utilize cutting-edge technology to analyze DNA samples and develop targeted treatments.
Researchers found that Slit repels young cells from their target destination, guiding them through the brain via concentration gradients. The discovery has implications for understanding neural migration and potentially treating neurological disorders such as Parkinson's disease and Alzheimer's.
The Wistar Institute's Recombinant Protein and Structure Evaluation Center has been admitted to the Ben Franklin Technology PArtners' Center of Excellence Network Program for the second consecutive year. The center provides services to small and medium-sized biotechnology and pharmaceutical companies, specializing in baculovirus expres...
A team of researchers found that tumor necrosis factor (TNF) may have a double-edged effect on brain-injured tissue, with potential benefits in chronic stages but harm in early stages. Blocking TNF in acute phases may be beneficial, while long-term recovery requires natural TNF presence.
Researchers at Massachusetts General Hospital discovered a critical protein called cryptochrome that assists per in regulating the mammalian clock's feedback loop. This finding effectively closes the gap in understanding the mechanisms behind human sleep-wake cycles and their disruptions.
The AVANT rotavirus vaccine demonstrated nearly 90% efficacy in preventing rotavirus disease in infants, surpassing existing vaccines' 49-68% efficacy rates. The vaccine was also found to be safe and immunogenic, with minimal side effects reported.