The U-M research will systematically study the proteins made by tumor cells, genes that instruct them, and subtle differences among proteins from different types of tumors. The goal is to develop rapid-analysis technology to detect cancer early and predict treatment response.
Günter Blobel's work on protein signaling discovered the importance of signal sequences in targeting proteins to their proper intracellular destinations. His research has led to a deeper understanding of protein trafficking, with implications for drug delivery and cellular processes.
A study of 2283 children aged 8-10 found that those living on farms were 3 times less likely to develop hay fever and asthma. Regular exposure to microbial antigens in stables may play a role in developing immune tolerance.
World leaders discuss economic, ethical and human rights issues underlying healthcare resource allocation for HIV/AIDS. The meeting highlights the need for better balance of resources between prevention and treatment, as well as access to essential drugs and treatments.
A Penn State researcher found that nearly three-fourths of women addicted to crack cocaine engage in prostitution to support their habit, highlighting the need for comprehensive support services. The study suggests that programs should offer housing, education, and job training to help these women escape poverty and addiction
Researchers have developed a model to study viral evasion and co-option of cellular defense strategies, revealing that persistent infection is achieved by suppressing cell suicide. Physiological changes occur, including slower growth and reduced virus infectivity over time.
Researchers used angle-resolved photoemission spectroscopy to study the electronic structure of Nd-LSCO, finding charge carriers segregated into one-dimensional lines and exhibiting quantum fluctuations that give rise to two-dimensional effects. This discovery may help resolve a paradox between different theories of superconductivity.
The new HIVWatch database, developed at UC San Francisco, tracks real-world treatment outcomes for patients with HIV disease. Preliminary data show an increase in CD4 cells among patients at their first clinic meeting, but a stable viral load, suggesting further analysis is needed.
Researchers at Thomas Jefferson University and Oxford University have found a promising drug against the hepatitis C virus (HCV), called N-nonyl-DNJ, which inhibits the activity of an important cellular enzyme, glucosidase. This drug may sidestep resistant viruses, a major problem with current treatments.
A recent survey by researchers at the University of Michigan Health System found that patients (70%) and physicians (83%) want to communicate via e-mail, but only 14% and 27% are currently using it. The study aims to facilitate electronic communication between patients and their doctors.
A study by Brown researchers has found that the brain releases a naturally produced cannabinoid called anandamide in response to pain. The substance produces analgesia and may provide a new approach to treating chronic pain, particularly in cases where opiates are ineffective.