Researchers developed a reliable blood test to diagnose diabetes in children at an early stage, allowing for prediction of the condition with a reliability of 50%. The test measures concentration of islet antibodies in a child's blood and combines it with DNA testing for hereditary susceptibility.
Researchers discovered a novel pathway controlling bone formation and density through the brain's hypothalamus, where leptin acts as a natural bone inhibitor. This finding offers potential treatment approaches for osteoporosis by manipulating the leptin pathway.
A research team has found that the immune system protein Crry is essential for fetomaternal tolerance in mice, preventing destruction of the developing fetus. Without this protein, complement components activate, leading to embryonic death and miscarriage.
A new report highlights the significant threat of emerging infectious diseases in wildlife to both human health and global biodiversity. The study reveals that many diseases have spread from domestic animals to wildlife populations through various means, including globalization, animal trade, and environmental changes.
Researchers at Yale have discovered new insights into the development of polycystic kidney disease (PKD), a life-threatening genetic disorder affecting millions. The study reveals crucial information about the PKD2 gene's role in normal development and its impact when mutated.
Researchers have produced the first 3-D structures of poliovirus in the moments after it attaches to and enters a host cell. The structures reveal tiny adjustments in the virus's protein shell that allow it to grab onto its host receptor more tightly.
Researchers at the University of Chicago discovered how neighboring skin cells adhere to form sealed barriers, a critical function for maintaining body fluids and keeping germs out. The study found that calcium concentration plays a crucial role in this process, enabling the formation of adherence junctions and 'puncta' between cells.
The percentage of Americans aged 65 and older in nursing homes has declined since the mid-1980s, with increasing numbers opting for assisted living and care within their own homes. This shift is attributed to declining disability rates among the elderly and the growing availability of alternative long-term care options.