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Science News for July 12, 2000


Two studies compare triple nucleoside therapy Ziagen® + Combivir® with protease inhibitorplus Combivir® regimens in therapy-naive patients

Two studies compare the efficacy and adherence of the triple nucleoside regimen of Ziagen/Combivir versus PI-containing regimens. Preliminary data show that patients on the Ziagen/Combivir regimen had better viral load suppression, with 68% achieving <400 copies/ml at 24 weeks, compared to 57% on the PI-containing regimen.

Multifaceted intervention program helps prevent asthma in high-risk infants

A randomized controlled study found a modest but significant reduction in asthma risk at 12 months in high-risk infants through a multifaceted intervention program. The program included avoidance of house dust mites, pet allergens, and tobacco smoke, as well as breastfeeding promotion and partially hydrolyzed formula supplementation.

SourceCenter for Advancing Health·JournalArchives of Pediatrics and Adolescent Medicine·DateJul 12, 2000