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Science News for March 23, 2000


How a hormonal henchman triggers death

Scientists discovered how ecdysone initiates a biochemical cascade controlling genes that destroy salivary gland tissues during Drosophila metamorphosis. The study reveals key components of the 'death cascade' and suggests potential connections to mammalian cell death programs.

SourceHoward Hughes Medical Institute·JournalMolecular Cell·DateMar 23, 2000

Fruit fly's genome sequence finished in record time: Physical maps are the key to accuracy

The Drosophila melanogaster fruit fly genome has been sequenced in full, with a focus on physical maps to ensure accuracy. The completion of the genome sequence is significant, as it reveals connections between fruit fly and human genes, offering insights into diseases such as cancer, kidney disease, and metabolic disorders.

SourceDOE/Lawrence Berkeley National Laboratory·JournalScience·DateMar 23, 2000

Cell division study aids cancer drug search

Researchers at the University of Glasgow have identified a complex of proteins that activate cell growth and division protein E2F, leading to excessive cell division and cancer. This breakthrough provides an opportunity to develop small molecule drugs that can arrest E2F activity and prevent tumour cell proliferation.

SourceUniversity of Glasgow_·JournalNature Cell Biology·DateMar 23, 2000
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Drosophilagenome sequence completed

The Drosophila genome sequence has been completed, providing valuable insights into human diseases and animal development. The sequence data reveals homologues for 60% of known genetic flaws causing disease in humans and 70% of genes involved in human cancers.

SourceHoward Hughes Medical Institute·JournalScience·DateMar 23, 2000

Manatees saved by ONR-supported technology

The Manatee Protection System uses acoustic sensors to detect manatees in the Port Canaveral locks, preventing collisions and saving their lives. The system's advanced technology, developed by ONR-supported scientists, has already saved five manatees during installation and early testing.

SourceOffice of Naval Research·DateMar 23, 2000

Mothers' depression may induce earlier puberty in daughters

A new study suggests that mothers' depression may cause their daughters to enter puberty earlier. Researchers found a correlation between maternal depression and the timing of puberty in adolescent girls. The study also discovered a link between exposure to unrelated adult men, such as stepfathers, and early puberty in girls.

SourceCenter for Advancing Health·JournalChild Development·DateMar 23, 2000
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