A new UF study contradicts dire predictions that prenatal cocaine exposure leads to misbehavior in toddlers. Researchers found no significant behavioral problems in cocaine-exposed children, suggesting poverty and environment may be the cause.
The conference brings together theoreticians and practitioners to discuss the application of algorithms in industry. Experts share their experiences and knowledge on topics such as enabling algorithm use, repository development, and meeting specific client needs.
The AAPS Workshop on Analytical Methods Post Approval Changes and Packaging Post Approval Changes brings together experts to discuss scientific issues related to post-approval changes. Speakers will explore viable approaches to predict the impact of these changes on drug quality.
Two studies in Annals of Internal Medicine explore cost-effectiveness of statins on specific populations. Statin therapy was found to be reasonably cost-effective for patients aged 75-84 years old with a history of heart attack, increasing life expectancy by four months while costing $18,800 per quality-adjusted life year. Cost-effecti...
Dr. Kisilevsky and his team aim to develop agents that prevent protein-carbohydrate binding, effectively inhibiting malaria parasite infection. The project builds on expertise gained in amyloid and Alzheimer's research, exploring novel ideas at a molecular level.
A large clinical trial is underway at UCSF to study a combination drug therapy for osteoporosis, using recombinant human parathyroid hormone (1-84) and alendronate. The trial aims to combine agents that speed up bone formation and resorption with those that slow down resorption, resulting in a net gain of bone strength.
Researchers have successfully created genetically engineered mice that cannot produce their own vitamin C, a nutrient essential for growth and healthy tissues. These 'humanized' mice will aid in understanding vitamin C's role in diseases such as heart disease and cancer.
Barbara Fredrickson's broaden-and-build model asserts that positive emotions broaden thinking and action, creating an upward spiral that builds strength, character, and health. Her research shows positive emotions reduce cardiovascular activity and increase psychological resilience.
The Virginia Heritage Project will create an integrated database of thousands of tagged finding aids describing the history and culture of African-Americans in Virginia. Researchers can access primary sources online, saving time and money.
A study by Princeton researchers estimates that 8-18 million Americans may identify with more than one race in the 2000 census, several times greater than previous estimates. The vast majority of likely multiple race respondents chose 'White' when faced with the traditional single-response race question.
The two-part documentary series explores how West Virginia became a separate state, with equal support for northern and southern causes. The series highlights the military actions and events that led to West Virginia's secession from Virginia and its subsequent development as a distinct state.
A new study reveals that older Latina women are at a higher risk of having low birth weight infants, contradicting previous assumptions. The research, which analyzed data from over 220,000 Mexican-origin Latina women, found that maternal age was a significant factor in determining infant birth weights.
Researchers sequenced a region of the house finch genome, showing similarities to mammalian genomes in structure. The study found that birds' compact genomes favor metabolic demands related to flight, supporting shared basic genome structure with mammals.
A new study suggests that most gamma radiation reaching Earth is leftover energy from massive shock waves caused by gravitational forces. The collision of electrons with low-energy photons could be a sign of ordinary matter captured within intergalactic clouds, shedding light on the 'missing matter' puzzle.
A four-month study of over 200 ambulance arrivals found potential for injury to children and other occupants in urban medical centers. Researchers identified opportunities for prevention, including securing EMS equipment and ensuring proper restraint.
Researchers are developing cost-effective methods to capture and store carbon dioxide, with potential to reduce global warming impact. The DOE-funded projects include membrane development, vortex tube separation, and algae-based carbon sequestration.
Researchers create molecular footprints of information to encode diverse data, including music, on a single silicon surface. The novel approach enables precise control over structure and chemical composition of nano-devices, potentially leading to breakthrough electronic tools.
Researchers found that higher doses of electroconvulsive therapy (ECT) were more effective in relieving depression, with 66.7% of patients experiencing relief compared to 38.9% on lower doses. However, the high-dose group also experienced temporary memory disturbances and longer recovery times.
A door-to-door campaign in Auckland, New Zealand raised awareness of meningococcal disease among at-risk populations. The campaign, initiated in 1998, used lay educators to visit over 11,000 homes and deliver key messages about the disease.
Researchers at OHSU have discovered new synapses between nerve cells and oligodendrocytes, suggesting a key role in myelin formation. These connections may help answer questions about how nerve cells regulate myelin production, potentially leading to treatments for multiple sclerosis.
Researchers at the University of Southern California have discovered a unique nuclear DNA structure that helps elucidate the process of immunoglobulin class switching. This finding may provide insights into B cell cancer, such as Burkitt's lymphoma.
A recent study published in Heart journal has found that recreational cocaine use promotes the formation of blood clots, leading to an increased risk of heart attacks. The research, which monitored 14 young adults after they received a dose of cocaine, showed that even occasional use can have significant effects on cardiovascular health.
Biologists at UCSD discovered that the Argentine ant's ability to thrive in California is due to its low genetic diversity, which allows it to recognize and accept individuals from the same colony. This has led to the formation of a single, large 'supercolony' that dominates native species.
A new Ohio University study reveals that e-commerce has increased the value of used and rare books, with online sales accounting for a 12.5% increase in book sales. The study also found that prices for rare books have climbed, while common titles have seen stabilization or decrease in price.
Astronomers have found evidence of a supermassive black hole similar to the one in our Milky Way in a nearby galaxy. The discovery was made using spectra from the Hubble Space Telescope and reveals details about the object's mass that could help scientists understand how these celestial phenomena are formed.
A new study found that two to three drinks significantly affect mariners' performance, making it twice as long to correct system failures after consuming alcohol. The researchers recommend lowering the current blood alcohol concentration limit for commercial ship personnel to mitigate this risk.
A University of Pittsburgh researcher found that children exposed to lead have a significantly greater odds of developing delinquent behavior. The study showed that delinquent youths had significantly higher mean concentrations of lead in their bones compared to non-delinquent controls, with results true for both whites and African Ame...
A large UM study found that mycophenolate mofetil (MMF) reduces the risk of losing a transplanted kidney due to chronic failure better than azathioprine (AZA). MMF protects against kidney loss even when acute rejection prevention effects are eliminated, with nearly 86% of MMF-treated kidneys surviving four years.
Molecular geneticists have characterized gene mutations in families with pseudoxanthoma elasticum (PXE), a rare inherited disorder that can lead to blindness, early heart attacks, and cardiovascular disease. The study provides the basis for DNA-based carrier detection, prenatal testing, and improved diagnosis of the condition.
Researchers at Oregon State University have discovered a new class of chemicals called 'bruchins' that signal a plant to form a benign tumor, helping prevent insect infestation. The unusual chemical can induce tumor formation even at low levels, with precise effects on the plant.
A recent study found that a half-day safety program for kindergarten students showed minimal improvement in basic safety skills. The research compared two groups of children, one that participated in the program and another that did not, but found no significant difference in their scores. This suggests that many safety programs, like ...
Researchers have used new methods to track the evolution of human chromosomes over a 130 million-year period, finding that one chromosome is shared only with chimpanzees. By examining analogous chromosomes in other mammals, scientists can reconstruct how human chromosomes evolved from ancient origins.
Researchers have developed a model called Reconstruction After Feedback with Take the Best (RAFT) that explains how hindsight bias occurs. Consistent with the model, experiments found that knowledge of nutrition values was updated with feedback, reducing hindsight bias.
Pediatric heart transplant patients with a specific cytokine gene profile may be identified as 'rejecters', indicating a higher risk of rejection. Researchers plan to evaluate the screening's value in tailoring immunosuppression to prevent serious episodes and graft loss.
A study by Thomas Jefferson University found that Pennsylvania's Early Discharge legislation resulted in longer hospital stays for new mothers and babies, increasing maternal and infant healthcare costs. The average maternity stay rose from 34 to 48 hours, with estimated annual costs of $20-25 million.
Researchers found that mice with a missing gene for Protein Kinase A drank twice as much alcohol and recovered in about 65 minutes from intoxication. The study suggests PKA may play a role in regulating voluntary consumption of alcohol and sensitivity to its effects.
A new international study found that parents of premature infants expressed strong interest in being involved in treatment and resuscitation decision-making. The majority felt that discussion on therapy was adequate, but suggested improvements could be made through better communication and simpler terminology.
Researchers found that PKA signaling regulates both alcohol-seeking behavior and sensitivity to alcohol intoxication in mice. Mice with a mutation in the RIIb subunit of PKA drank nearly twice as much 20-percent alcohol solution, while recovering faster from sedative effects.
A new UCSF study has analyzed data from 1.5 million births to Mexican-born Latinas, U.S.-born Latinas, and U.S.-born White women, revealing lower rates of tobacco use and medical complications among Mexican-born Latina women.
Research found that psychologically abused women experienced higher rates of disability, chronic pain, and other physical health issues compared to non-abused women. The study also highlighted the need for effective clinical- and community-based interventions to address intimate partner violence in women's lives.
A study by University of Pittsburgh surgeons found that liver cancer patients wait nearly a year for transplants, allowing tumors to grow too large to be cured. Modifying the policy could improve survival rates for Stage IV patients with four or more nodules less than 3 cm.
Two Hopkins studies confirm prenatal exposure to normal male hormones dictates male gender identity in genetically male children born with cloacal exstrophy. Most reassigned as females later reassign themselves back to males, exhibiting strong male behaviors and attitudes.
A new study from Michigan Medicine found that three-quarters of US states cover alternative therapies like chiropractic care and hypnosis for low-income children through Medicaid. The study suggests that more research is needed on the quality of care and outcomes of these treatments, particularly when combined with conventional medicine.
Visitors to NASA's Marshall Space Flight Center will enjoy live performances by country, rock, pop, and gospel artists while exploring rocket firings, space exhibits, and facility tours. The event also features appearances by NASA astronauts and real space flight hardware.
Researchers at Cornell University have developed a nanofabricated device that can separate DNA fragments by length in as little as 15-30 minutes, compared to the traditional method which takes 12-24 hours. The device uses alternating deep and shallow sections to propel DNA strands through it, allowing for faster separation and analysis.
A new study documents the increase in Ritalin-type stimulant drugs and Prozac-type antidepressants prescribed to children, raising concerns about diagnosis and treatment. Thirty percent of children on SSRIs also took stimulants, highlighting the need for further research on safety and effectiveness.
A team of researchers has discovered two nearly complete fossil skulls from the Dmanisi site in Georgia, which may represent the first hominid species to migrate out of Africa. The fossils show clear signs of African ancestry and are dated to around 1.7 million years old.
Future wireless devices may use multiple antennas to outperform single-antenna versions, reducing interference and increasing reception accuracy. This technology could enable three times as many users to operate within the same frequency band.
A new study contradicts the long-held assumption that the Helicobacter pylori bacterium has been with humans forever. Researchers analyzed DNA from over 500 strains from five continents and found that strains from Peru resemble those from Spain, not those from eastern Asia.
Student engineers at Johns Hopkins University designed a low-tech, affordable childproofing device for handguns that can be defeated by adults but not young children. The device automatically switches the gun back to safe mode when it leaves an adult's hand, providing passive protection.
Researchers found evidence of El Niño-like climate changes in New England during the Ice Age, revealing a strong three-to-five-year cycle of activity. This finding provides new insights into El Niño's persistence under different climate conditions.
Researchers have found nearly complete fossil cranium and skullcap in Dmanisi, Georgia, dating back to 1.7 million years ago. The discovery suggests early human species may have left Africa earlier than previously thought, with the possibility that they were driven by appetite for more protein.
A new Penn State study reveals that restrictive feeding practices can pass eating problems from mother to daughter as early as five years old, increasing the risk of childhood overweight. Mothers who control their own weight tend to use more restrictive feeding practices, which can actually promote patterns of intake influenced by pala...
A molecular-level malfunction in patients with heart failure can be repaired with existing treatments, suggesting a new approach to treating the root cause of the disease. The research reveals that a malfunctioning calcium channel is responsible for the defect, and beta blockers may prevent or reverse its development.
Researchers discovered that low nitric oxide levels in mouse newborns with hypoplastic lungs hinder the proper development of blood vessels, leading to persistent pulmonary hypertension and respiratory distress. The study aims to identify genes affecting lung development and function.
The Chandra X-ray Observatory has imaged the full impact of Supernova 1987A for the first time, revealing a shock wave smashing into the outer parts of a ring at 4,500 km/s. The gas behind the shock wave has a temperature of ten million degrees Celsius.
A new study reveals that even in countries with universal healthcare, there are significant restrictions on prescription drug accessibility for the elderly. The research found that countries like Australia, Canada, and the UK have varying levels of outpatient pharmaceutical plans, but often come with high costs.
The Fred Hutchinson Cancer Research Center is proud to announce that five of its researchers have been selected as Howard Hughes Medical Institute (HHMI) investigators. Drs. David Baker, Philip Green, and Michael Shadlen from the University of Washington, and Drs. Leonid Kruglyak and Cecilia Moens from the Fred Hutchinson Cancer Resear...
A new Harvard Medical School study found that only 14% of patients treated for three common mental illnesses received adequate care. African-Americans and those without insurance coverage are less likely to receive satisfactory mental health care.
David Wetzel's new technique uses infrared microspectroscopy to analyze small specimens without grinding or staining, revealing localized chemical content and spatial resolution. The technology has increasing applications in biological and other research, including rare blood disorders and hit-and-run cases.