Researchers used X-ray crystallography to determine the structure of COX-2 with arachidonic acid bound, gaining insights into its interaction with inhibitors. The study's findings may help guide future drug development for pain, inflammation, and cancer treatment.
Researchers created self-assembling ink that forms nanoscopic pores with external function and internal structure. The new ink can be easily printed from ordinary printers or written by lithographic pens.
The Apes: Challenges for the 21st Century conference addresses pressing issues affecting gorillas, orangutans, chimpanzees, bonobos, gibbons, and siamangs in both their natural habitats and zoos. The event brings together leading researchers to develop action plans on conservation, husbandry, and other key topics.
The Canadian Arthritis Network hosted a conference showcasing advancements in arthritis research and one-stop services for industry and government. The event featured key developments in therapeutics, diagnostics, and devices.
Research suggests that occupational lead exposure significantly increases the risk of developing Alzheimer's disease, particularly among those working in jobs with high levels of lead exposure. The study found a strong correlation between lead exposure and Alzheimer's, while other metals such as aluminum and solvents were not associate...
A team of scientists identified Io as the dominant source of the Jovian dust streams, which are high-rate bursts of submicron-sized particles. The particles' motion is strongly influenced by Jupiter's magnetic field, providing a unique signature that could only be present if Io were the dominant source.
A new NIH clinical advisory statement recommends using systolic blood pressure as the primary criterion for diagnosing and treating hypertension in middle-aged and older Americans. This shift aims to improve outcomes by targeting systolic pressure, which is associated with a higher risk of heart disease.
A new University of North Carolina at Chapel Hill study suggests that benzene is responsible for between 8% and 48% of all smoking-induced leukemia deaths. The chemical also causes between 12% and 58% of smoking-related deaths from acute myeloid leukemia.
A study found that medical students' biases against black female patients with chest pain can affect clinical decisions. White male students rated a black female patient as having less desirable health status but considered the white male patient's coronary condition more severe.
A study of 31 prostate cancer patients found that quality of life returns to normal within a year following brachytherapy, with urinary symptoms disappearing. The treatment was compared to other options like removal of the prostate or standard radiation therapy, which carry higher risks of decreased sexual function and bowel problems.
The University of California, San Diego has secured $47 million in private support to build a state-of-the-art cancer facility, with John and Rebecca Moores committing $20 million towards the project. The facility will bring together over 300 physicians, scientists, and staff to provide advanced patient care and conduct research.
A study of retired football players found that over half had experienced concussions, leading to increased risk of neurological complaints such as memory problems and numbness in extremities. The survey suggests that repeated blows to the head may cause lasting damage, prompting calls for regular testing to monitor player health.
Scientists have identified an unusual protein in anaerobic bacteria that senses oxygen and causes the bacteria to swim away from it. The protein could lead to the development of new antibiotics and provide insight into the evolution of life.
Scientists are using lasers to detect gravitational waves, which could help study dark matter and unlock the universe's secrets. The technique involves splitting a laser beam into two halves and comparing them for minute movements caused by space stretching.
The NHLBI has released a clinical advisory emphasizing the importance of systolic blood pressure in diagnosing and treating hypertension in middle-aged and older adults. The guideline recommends reducing systolic blood pressure to less than 140 mm Hg to reduce heart attack, heart failure, and stroke risk.
A study presented at the American Academy of Neurology's annual meeting found that sudden falls among the elderly can be related to an overlooked inner ear disorder. Successful treatments are often available once the correct diagnosis is made, with excellent surgical success rates in older individuals.
Chemists at Washington University in St. Louis have created knedel nanoparticles that mimic viruses and show potential for a new direction in gene therapy and other biomedical applications. The nanoparticles can escape detection by the immune system and are designed to behave like viruses, but without the risk of live virus effects.
A new study will investigate whether cognitive therapy can prevent relapses and recurrences of major depression as effectively as standard antidepressant medication. The study, funded by a $1.6 million NIMH grant, aims to help patients who suffer from recurring episodes of major depression.
Volunteers use virtual reality helmet and computer program to take actions like turning on TV or stereo by simply wishing it so, in breakthrough study that may someday enable patients with extreme paralysis to regain control of their surroundings
Researchers found that spices can shield bacteria from irradiation by protecting their DNA, with chili and black pepper offering the highest protection. The study suggests spice extracts could be used to protect healthy tissue in radiation therapy.
A new study found that asthma patients who experience more depressive symptoms have a lower quality of life. The study also showed that household income is negatively correlated with the level of depressive symptoms among patients.
Researchers at San Francisco State University discovered that blister beetle larvae mimic female bees as part of a three-step strategy to infiltrate and parasitize the bee's nest. The larvae use cooperative behavior to lure male bees into pseudocopulation, which then transport them to multiple females.
Patients with serious neurological conditions have a better chance of survival in Neurological/Neurosurgical Intensive Care Units (Neuro-ICU) compared to general ICUs. The study, presented at the American Academy of Neurology's Annual Meeting, found a 3.3-fold increase in hospital mortality among patients not in a Neuro-ICU.
Researchers at Washington University School of Medicine found that most household members were exposed to significantly less radiation than the government allows. The study's findings suggest that outpatient care for thyroid cancer patients is safe and poses minimal risk to those around them.
A nine-year study found that African-American women are 2.4 times more likely to develop diabetes due to lifestyle factors such as poor diet and lack of exercise. The study suggests that adopting a healthier lifestyle can help reduce the risk of developing diabetes in this population.
A 150-ton magnet has passed its initial operating test in Japan, producing a magnetic field of 13 Tesla and storing 640 megajoules of energy. The successful test demonstrates superconducting performance parameters and manufacturing methods for larger magnets planned for the International Thermonuclear Experimental Reactor (ITER).
Research finds that people typically focus on lower facial expressions when interacting with others, but these can be misleading. Studying brain activity, researchers discovered that the upper face is more closely tied to a person's true emotional state.
Insomnia is a prevalent and serious condition that can have serious consequences. Effective treatments include identifying underlying causes, such as lifestyle habits, medical conditions, or medications, and adopting good sleep hygiene practices, like restricting bedtime, avoiding naps, and increasing exercise.
A study of 50 patients at the Veterans Affairs Medical Center in Atlanta found that rectally administered lidocaine gel significantly reduced pain during transrectal prostate biopsy. Patients who received lidocaine rated their pain as moderate to severe, while those without anesthetic experienced more discomfort.
A study published in AIDS found an association between osteopenia and protease inhibitors, a class of medications used to treat HIV/AIDS. Researchers discovered that patients taking these medications were more likely to develop low bone-mineral density, which can lead to fractures.
Researchers found that human papillomavirus (HPV) is associated with a subset of head and neck cancers, particularly those of the oropharynx, which are more likely to be caused by HPV. The study also showed improved survival rates among patients with HPV-positive tumors compared to those with HPV-negative tumors.
Chlordane, a persistent organic pollutant, accumulates in the human body and can cause digestive and nervous system disorders; washing food before eating can reduce exposure risk
Researchers at Fred Hutchinson Cancer Research Center have discovered a novel agent that can prevent transplant reactions and promote immunological tolerance. The treatment, using an anti-CD28 antibody, could lead to safer and more effective transplants, reducing the risk of graft-versus-host disease.
A new vaccine technology has demonstrated a dramatically enhanced immune response in mice against tumor growth and infection. The PIC vaccine bypasses key steps in the normal chain of events leading to immune response, directly targeting the cellular switch to muster a potent attack on foreign proteins.
According to a study published in JAMA, the overall percentage of alcohol-related motor vehicle deaths among children has declined from 21.6% in 1991 to 17.8% in 1996. The majority of these fatalities involved minors as passengers, with 79.5% of alcohol-related deaths resulting in child passenger fatalities
The American College of Physicians-American Society of Internal Medicine has released new guidelines for treating depression with antidepressant drugs. The guidelines highlight the effectiveness of both older and newer medications, as well as the potential risks associated with St. John's wort. Patients should consult their doctor to d...
New antidepressant guidelines suggest both older and newer medications are effective in treating depression. A population-based study found that overweight women are less likely to receive screening for cervical and breast cancer, despite higher mortality rates from these cancers.
A new study suggests that ginkgo extract may help protect the brain against stroke damage by reducing the extent of brain damage caused by free radicals. However, more work is needed to determine the proper dose and ensure its safety for humans at risk for stroke due to potential blood-thinning risks.
The Navy is hosting its first annual Naval-Industry R&D Partnership Conference to discuss reducing barriers between government and commercial industries. The conference aims to leverage commercial products and technology to maintain advanced capabilities and reduce costs.
Researchers from MGH discover that a protein called SDF-1 not only attracts but also repels T cells at high concentrations. This finding opens up potential new ways to manipulate the immune system for treatment of autoimmune diseases and organ transplantation.
Researchers at Penn School of Medicine have developed a prototype of an integrated database that can instantly retrieve and store digital breast images from mammography facilities across the country. The project aims to improve detecting and diagnosing women with breast cancer in a more controlled and cost-effective manner.
Canadian Medical Association Journal article highlights lack of consensus among otolaryngologists on indications for ear tube insertion in children. Only 6 of 17 factors and 1 of 4 clinical vignettes were agreed upon, suggesting a need to revisit clinical practice guidelines.
The new system can analyze many samples within seconds, nearly 5,000 times faster than other technology in screening samples of catalysts that react with liquids. It will speed up the analysis of combinatorial chemistry samples and reveal molecular mechanisms involved in gas-solid catalysis.
According to a study published in JAMA, African American women and men are more likely to develop type 2 diabetes than their white counterparts. The researchers found that being overweight was a significant factor in the excess risk for African American women, while high blood pressure was a key contributor for African American men.
A new study found that work/family spillover has distinct effects on physical and mental health, with both negative and positive spillover exerting separate impacts. Positive spillover was independently associated with better health, while less negative spillover was linked to improved well-being.
The study suggests that teenagers' recommendations can inform effective school-based obesity prevention programs, prioritizing fun and interactive activities over weight control. Schools can also create support groups specifically for overweight youth, leveraging their resources to provide low-cost programs.
Falling fertility rates in sub-Saharan Africa may signal the first steps towards a balanced population, adequate food supplies, and relative economic stability. The region's population is expected to increase from 650 million to 1.5-2 billion by 2050.
A review of Canada's waiting lists reveals a need for better infrastructure and information about management approaches, contradicting frequently offered solutions. The authors conclude that information defects are often misdiagnosed as financial shortages, leading to forced decision-making.
Towns that vigorously enforced youth tobacco laws had lower crime rates, including violent and property crime. The association suggests a potential link between strong enforcement and crime prevention.
A new technology developed by Dr. Lawrence Larsen at Sandia National Laboratories can treat benign prostatic hyperplasia (BPH) without surgery, reducing side effects and costs. The non-invasive procedure uses radio frequency energy to kill excess cells, shrinking the prostate gland and alleviating urinary obstruction and pain.
A study found that 64% of alcohol-related child passenger deaths involve a child riding with the drinking driver, emphasizing the need for deterrents such as lower legal blood alcohol limits and child endangerment laws.
Researchers at UCSF found that excessive water consumption during marathons can lead to fatal brain swelling and fluid leakage into the lungs, a condition known as hyponatremia. Intravenous salt treatment has been shown to be effective in treating hyponatremia.
Scientists found that even in desolate areas, protected plants like seeds, spores, and root balls could sprout new life. The standing dead trees and debris acted as 'lifeboats' for plants and animals, adding complexity to the recovering ecosystem.
A new study by the University of North Carolina at Chapel Hill finds that drinking drivers are responsible for a significant number of child passenger deaths in the US. Between 1991 and 1996, approximately 550 U.S. children died each year in crashes involving drinking drivers, with about one in five deaths involving alcohol.
A new Cornell University study reveals that household chores such as scrubbing, mopping, and vacuuming are still among the most tiring tasks, similar to those found in a 1937 survey. The researchers recommend redesigning these processes to reduce strain and fatigue.
Researchers test new fragrances to bait coyotes into consuming birth control drugs, aiming to reduce attacks on livestock and wildlife. The approach aims to decrease the need for lethal methods like shooting, which have cost farmers millions in lost earnings.
A new study finds that men with high blood pressure, weight and cholesterol levels in their 50s are more likely to develop vascular dementia in their late 70s. The research suggests that reducing these risk factors may help delay the onset of dementia, but more large-scale studies are needed to confirm the findings.
A longitudinal study of 291 students found that their diets became less healthful as they transitioned from childhood to adolescence. Breakfast and fruit consumption decreased significantly, while soft drink consumption increased.