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Science News for October 9, 2000


Fred Hutchinson Cancer Research Center's Puget Sound Oncology Consortium to participate in nationwide study to evaluate benefit of Herceptin therapy

The Puget Sound Oncology Consortium is partnering with the National Surgical Adjuvant Breast and Bowel Project to evaluate Herceptin therapy in women with early stage breast cancer. The trial, Protocol B-31, aims to assess the safety and efficacy of combining Herceptin with chemotherapy in treating node-positive breast cancer patients.

Driving differentiation of human embryonic stem cells

Researchers at Howard Hughes Medical Institute successfully directed human embryonic stem cells to differentiate into three germ layers: ectodermal (brain, skin), mesodermal (muscle) and endodermal (liver and pancreas). The study suggests that a combination of growth factors may be needed to achieve specific cell lineages.

SourceHoward Hughes Medical Institute·JournalProceedings of the National Academy of Sciences·DateOct 9, 2000