Jean M.J. Frechet, a renowned Berkeley chemist, has been honored with the 2001 Arthur C. Cope Scholar Award for his groundbreaking research on dendrimers, complex organic compounds with various applications, including drug delivery to tumors and light-harvesting antennae.
Researchers at Dartmouth/VA reveal that operative mortality for major surgery varies significantly by procedure and patient age. Elderly patients face two- to four-fold higher mortality risks than younger patients, highlighting the need for more realistic estimates in decision-making.
Researchers will model and study supernovae to discover how they occur and the complex physical processes involved. They aim to understand challenging issues in theoretical and computational physics, advancing national security interests.
A chemist at Ohio State University has won a national award for his work on studying reactive intermediates in chemical reactions. He is using high-tech techniques to 'freeze-frame' these ephemeral species, which are crucial in determining the success or failure of reactions.
Researchers at the University of Illinois Chicago have developed a fluorous chemistry-based method to convert alcohols into aldehydes and ketones, retaining the convenience of the Swern reaction. The new reagents eliminate the byproduct dimethyl sulfide, producing an odorless and easily recyclable alternative.
Researchers at Howard Hughes Medical Institute developed a new parallel focusing method to solve the Poisson-Boltzmann equation, enabling efficient simulation of complex biomolecules. This approach allows for high-resolution modeling of molecules like microtubules and ribosomes, providing insights into their collective properties and p...
Smoking cessation can lead to significant improvements in heart disease risk factors within a few weeks of quitting or reducing smoking. The sooner an individual quits, the more substantial the benefits will be.
Jeffery W. Kelly's work focuses on designing and utilizing small molecules to prevent neurodegenerative diseases similar to Alzheimer's but more rare. His team's molecular braces are now in preclinical trials for disorders like familial amyloid polyneuropathy.
Research finds that student activism is linked to extracurricular involvement and a strong social network. Students who are well-established in campus life are more likely to participate in protests.
A study found raw (uncooked), contaminated alfalfa and clover sprouts cause illnesses in California, leading to six outbreaks of salmonellosis and E. coli 0157. Researchers also discovered that hormone replacement therapy (HRT) may help lower blood pressure in women as they age.
The Terra satellite beams daily images of western U.S. wildfires to NASA, which are then transmitted to the Forest Service. The collaboration uses MODIS data to create Active Fire Maps that help resource allocation decisions and aid in public understanding of fire locations.
John Montgomery, a Wayne State University chemist, has developed a new method to create complex molecules efficiently. He achieves this by making multiple bonds at once, using catalysts based on reactive nickel.
A study found that emotional smokers have a harder time quitting due to the urge to smoke triggered by anger or anxiety. The research also revealed gender differences in emotional triggers of smoking, with men more likely to smoke when angry and women more likely to smoke when happy.
A new enzyme increases the number and size of heart muscle cells in mice, allowing them to live longer. This discovery could lead to gene-based therapies for heart disease, with potential benefits for millions of Americans affected by the condition.
A study by Dartmouth Medical School researchers found significant regional variation in neonatal intensive care workforce distribution, with cities like Washington DC and Newark NJ having higher numbers of neonatologists. The team's findings suggest that more resources do not necessarily lead to better outcomes for newborns.
Chemist Nicole S. Sampson has made significant breakthroughs in understanding the process of fertilization, discovering that protein fertilin-beta binds to egg protein alpha-6 beta-1 integrin. Her research could lead to new applications for sperm mimics and insights into tissue formation.
Murray Goodman, a bioorganic chemist at the University of California, San Diego, has developed new strategies to create more effective and selective drugs. His research aims to mimic the action of peptides, which help direct processes in the body, and improve upon their natural opioids.
Researchers created atomic-resolution maps of microtubules and ribosomes to understand their functions in transporting drugs like taxol. The maps revealed areas that play a key role in intracellular transport, with potential binding sites for such drugs.
A study by Steven M. Ortiz finds that athlete wives develop coping strategies to deal with the stress of infidelity, often using humor or changing boundaries of trust. The wives who marry athletes for glamour and money may be more accepting of their husbands' affairs.
A new study by Harvard Medical School researchers suggests that complementary and alternative medicine (CAM) is here to stay for the foreseeable future. The use of CAM therapies has steadily increased in popularity since the 1960s, with the largest growth rate occurring during the transition from the 1960s to the 1970s.
Researchers are conducting field studies on three Hawaiian islands to examine the origins and evolution of plant life on Earth. The team is collecting plant samples in various ecosystems to identify invasive species and determine their impact on native biodiversity.
Physicists at Brookhaven National Laboratory have produced a significant number of 'doubly strange nuclei', containing two strange quarks, to study nuclear forces and neutron stars. The discovery uses statistical techniques to infer the presence of these nuclei, which may provide insight into the properties of neutron stars.
Corn-based biodegradable plastics have won a national award, thanks to Cornell chemist Coates' innovative work in developing polymers that can be easily absorbed by the environment. His research has also led to new applications, such as sutures and drug delivery systems.
University of North Carolina chemist Michael T. Crimmins wins national award for developing laboratory methods to create compounds with anti-tumor activity and potential health benefits. His team successfully synthesized a chemical from the gingko tree called gingkolide B, which may also delay Alzheimer's disease onset.
Researchers analyzed lake sediment samples to find two naturally occurring warm periods in Alaska spanning 2,000 years. The initial period occurred from A.D. 0-300 and was accompanied by drier conditions; the second period corresponded to the Medieval Climatic Anomaly, a global warming event.
Richard R. Schrock has developed catalysts that make molecules efficiently, leading to discoveries of potential antibiotics and anticancer compounds. His work significantly influences the field of organic chemistry.
Dr. Duane Grandgenett receives nearly a million dollars in grants to study ways of inhibiting HIV replication in humans. He aims to develop an HIV inhibitor targeting the integrase protein, which plays a crucial role in the virus's survival.
Victor Snieckus has invented more efficient methods for creating organometallic compounds, which have applications in pharmaceuticals, agriculture, and electronics. His research has led to the development of a new painkiller, fungicides for wheat crops, and conducting materials.