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Science News Archive 2002 - Page 10


Page 10 of 93

Genotyping targets individuals at high risk for H. pylori-associated stomach cancer

A study has identified specific combinations of H. pylori bacterial strain and host genetic variations that increase the risk of stomach cancer in infected individuals. These findings suggest that personalized genotyping can help identify high-risk individuals, who may benefit from targeted H. pylori eradication treatment.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateNov 19, 2002

Other highlights in the November 20 issue of JNCI

Two new studies published in the Journal of the National Cancer Institute identified key risk factors for classical Kaposi's sarcoma and found that smoking may decrease the risk of this disease. Meanwhile, research on leptin suggests it controls breast cancer cell proliferation. Additionally, a potential screening tool for ovarian canc...

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateNov 19, 2002

JCI Table of Contents, November 18, 2002

Researchers discover two compounds that inhibit parathyroid hormone-related protein production in human breast cancer cells, reducing metastatic bone breakdown and calcium levels. The findings suggest a novel therapeutic approach to treating bone metastasis and hypercalcemia in breast cancer patients.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateNov 19, 2002

Researchers create DNA 'nanocircles' to probe the mystery of aging in human cells

Scientists at Stanford University have created synthetic DNA nanocircles that can lengthen telomeres in test tube cells, a key factor in determining cell lifespan. This breakthrough could lead to the development of new methods for studying aging and cancer, as well as alternative approaches to transplantation medicine.

SourceStanford University·JournalProceedings of the National Academy of Sciences·DateNov 19, 2002

Blood proteins tied to inflammation

Researchers found that high levels of C-reactive protein and low albumin are associated with a higher risk of cardiovascular disease in dialysis patients. The study, which followed over 1,000 patients for four months, found that these proteins can identify patients at high risk before heart events occur.

LSUHSC research shows drug blocks enzyme that activates bacterial and viral toxins

A new peptide, D6R, has been developed by LSUHSC researchers to block the action of an enzyme that activates toxic proteins in bacteria and viruses. The peptide was found to protect cells from lethal toxins without triggering a cytokine response, offering potential as a treatment for sepsis and other infections.

SourceLouisiana State University Health Sciences Center·JournalInfection and Immunity·DateNov 18, 2002

Life expectancy following diagnosis of Alzheimer’s disease depends on age at diagnosis

The study found that median survival times for Alzheimer's patients vary significantly depending on the age at diagnosis, ranging from nearly 9 years for those diagnosed at 65 to approximately 3 years for those diagnosed at 90. Additionally, researchers reported an average time of 2.8 years between symptom onset and diagnosis.

SourceJohns Hopkins Bloomberg School of Public Health·JournalArchives of Neurology·DateNov 18, 2002

Nation's two largest medical specialty groups issue migraine treatment guidelines

The American College of Physicians and the American Academy of Family Physicians have released new guidelines for treating migraines, recommending immediate treatment with NSAIDs or triptans, as well as managing nausea and vomiting symptoms. The guidelines also emphasize the importance of patient involvement in charting migraines and i...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateNov 18, 2002

American Thoracic Society Journal news tips for November (second issue)

Researchers found that halting COPD treatment with inhaled corticosteroids increases exacerbation risk and worsens quality of life. Men are more prone to pharyngeal collapse due to longer airways, which may contribute to their higher obstructive sleep apnea risk. Additionally, patients with OSA showed reduced brain gray matter volume, ...

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateNov 18, 2002

Assisted reproduction may be linked to birth defect syndrome

Researchers have found a possible association between IVF and an increased risk of Beckwith-Wiedemann syndrome (BWS), a genetic disorder that can predispose children to cancer. BWS is characterized by excessive growth and occurs in about 1 in 15,000 births, with the incidence being significantly higher among IVF-conceived babies.

SourceJohns Hopkins Medicine·JournalAmerican Journal of Human Genetics·DateNov 15, 2002