A 10-year study of over 6,500 patients with diabetes undergoing major vascular operations revealed a mortality rate of only 1 percent. The study's findings contradict previous research and suggest that patients with diabetes should be offered the same surgical options as those without diabetes.
Scientists have developed a new 'gene silencing' strategy using short hairpin RNAs (shRNAs) that can efficiently silence specific genes in mammalian cells. This technique has the potential to revolutionize gene function exploration and could lead to targeted therapies for cancer, AIDS, and other diseases.
Researchers have successfully mapped the genetic regions responsible for Hirschsprung disease, a rare inherited disorder affecting the intestines. The study reveals that three crucial regions on chromosomes 3, 10, and 19 contribute to the disease's complex inheritance pattern.
During adolescence, the brain undergoes significant changes, gaining scope and depth of knowledge and comprehension but losing ability to acquire new sounds and speech patterns. Research on post-mortem cerebral cortexes reveals that nerve cells undergo pruning or streamlining during this period.
Researchers at The Wistar Institute have identified a new enzyme required for silencing certain genes, which can lead to cancer. The discovery could lead to new cancer therapies by targeting the enzyme's activity.
Adult neural stem cells isolated from rats' brains can mature into functioning brain cells, forming normal neuronal structures and connections. The study's findings suggest potential for clinical application in regenerating damaged brain tissue.