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Science News for August 11, 2002


Researchers find gene that causes leukemia in children with Down syndrome

Researchers have found a gene mutation that causes acute megakaryoblastic leukemia in children with Down syndrome, increasing their risk by 10-20 times. The discovery highlights the importance of GATA1, a transcription factor regulating red blood cell and platelet production.

SourceUniversity of Chicago Medical Center·JournalNature Genetics·DateAug 11, 2002