Researchers identify XOR as essential for enveloping milk fat droplets with phospholipid bilayer. Heterozygous XOR-mutant females fail to secrete milk fat, leading to premature involution of mammary gland and lactation insufficiency.
SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateDec 14, 2002
Scientists have developed a new mouse model of lipoatrophic diabetes, which reveals the genetic pathway underlying the disease. The study also suggests that leptin therapy may be effective in treating humans with lipoatrophic diabetes.
SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateDec 14, 2002