Researchers discover 3-bromopyruvate selectively kills liver cancer cells while sparing healthy tissue. The compound, which blocks energy production in cells, may offer a promising alternative to existing treatments for liver cancer.
Researchers found that cardiopulmonary bypass surgery can cause impaired memory and attention, which persist beyond the first couple of weeks. The study suggests that brain systems supporting attention may be particularly vulnerable during major surgeries.
A recent study reveals that mutations in the FBN1 gene can cause Marfan syndrome by disrupting an exonic splicing enhancer, leading to exon skipping and compromised fibrillin protein activity. This understanding may help explain other human diseases associated with exon skipping.
Researchers have identified G9a as a chromatin-modifying enzyme essential for normal development. Studies show that G9a deficiency leads to severe developmental growth retardation and increased programmed cell death, highlighting the enzyme's critical role in regulating gene expression during embryogenesis.