A recent study published in Alcoholism: Clinical & Experimental Research found that transit employees with heavier weekly drinking rates were more likely to experience trauma on the job. The study suggests that off-the-job drinking can have costly impacts for workers and transit agencies, highlighting the importance of considering fact...
The USPSTF recommends that physicians routinely screen women over 65 for osteoporosis, a thinning of the bones that can lead to bone fracture. Women at higher than average risk should begin screening at age 60. Early nephrologist care is associated with better outcomes for kidney disease patients, particularly those with African-Americ...
A team-based approach to care significantly reduces hospital stays and the risk of blood clots in patients with stroke. The study, published in the Canadian Medical Association Journal, found a $2.1 million annual savings per 1000 patients treated.
A new study found that moderate alcohol consumption increases levels of good cholesterol, reduces inflammation, and protects against heart disease in post-menopausal women. The research suggests that drinking in moderation may be beneficial for women's heart health after menopause, similar to men.
A study of 818 fatally injured drivers found a strong association between blood alcohol content (BAC) and problem drinking. Despite this, over 40% of drivers with high BACs were not reported as problem drinkers by their spouses, highlighting the need for targeted countermeasures.
Researchers have successfully delivered the full-length dystrophin gene to mice with muscular dystrophy using stripped-down vectors, restoring normal muscle function. The breakthrough could pave the way for human clinical trials to assess the safety of this method in patients.
Researchers tracked water molecule movement on palladium surface, discovering clusters of two to six molecules exhibiting high mobility when bound together. The formation of hexamers led to stable honeycomb structures, which spread out and interacted with the substrate's lattice.
A study found that prenatal alcohol exposure can impair reaction times, particularly when processing multiple signals. Children with prenatal alcohol exposure showed slower premotor and motor reaction times, indicating difficulties in both central and peripheral processes involved in information processing and action planning.
Researchers found that women married to alcoholics are more likely to meet criteria for alcoholism themselves, use illicit drugs, and be current smokers. The study also suggests that understanding the mother's characteristics is crucial in interpreting the father's AUDs.
A novel gene therapy technique developed by Stanford researchers allows for the integration of large genes into human chromosomes, enabling continuous production of proteins. This technique has the potential to treat a variety of diseases, including Duchenne's muscular dystrophy and cystic fibrosis.
Researchers have identified a genetic link between macrophage scavenger receptor-1 (MSR1) and increased risk of prostate cancer. MSR1 mutations were found in approximately 12.5% of African American men with prostate cancer, compared to 1.8% without the disease.
The study identified specific genes regulated by Nrf2 in response to sulforaphane, a compound found in broccoli that can annihilate a broad spectrum of carcinogens. By understanding how this process works, researchers may develop new cancer preventive agents.
A research team led by Wake Forest and Johns Hopkins universities found that mutations in the MSR1 gene are associated with an increased risk of aggressive prostate cancer, particularly in African-American men. The study identified seven potentially important mutations of the MSR1 gene, including one that leads to rapid metastasis.
A recent study found that almost 33,000 pregnant women were involved in car crashes every year between 1995 and 1999. The researchers also discovered that younger women, aged 20-29, are more likely to be involved in car crashes during their peak childbearing years.
A new study has found that a second set of immune cells, known as regulatory T cells, prevent attack cells from acting against cancer. The study discovered that these regulatory T cells communicate with the attack cells via a messenger chemical called TGF-beta.
Researchers found that a single fly gene encodes two proteins with opposing actions: one inhibits the other's activity. This discovery provides insight into complex biological phenomena and may lead to novel treatments for human cancers, particularly those with overactive STAT proteins. The study highlights the importance of considerin...
Researchers have isolated a key component of cell death signals that can be targeted to prevent cancer growth. By understanding how these signals interact, scientists hope to develop new anti-cancer therapies.
Dogs on a reduced-calorie diet lived up to 13 years, while those with high-calorie diets averaged 11.2 years. The study also found that lean body conformation and dietary restriction can help prevent chronic illnesses like osteoarthritis.
Researchers conducted a Phase I clinical trial of endostatin, showing that it decreases blood flow to tumors and promotes the death of cancer cells. The study also found minor anti-tumor activity in two patients, but no long-term responses were seen.
A new generation antipsychotic quetiapine, combined with mood stabilizers, shows improved efficacy in treating manic symptoms of bipolar disorder. The study results indicate that more patients experience full resolution of manic symptoms when treated with quetiapine.
Researchers at Argonne National Laboratory are developing an ice slurry procedure to cool the blood and brain cells after cardiac arrests, with the goal of improving survival rates. The ice slurry cools the brain by 2-5 degrees Celsius quickly, giving medics more time to revive normal blood flow and brain activity.
A global consensus on histopathological diagnostic criteria for Parkinson's disease is within reach thanks to an interactive website. NMDA receptor antagonists failed to show efficacy in clinical trials of stroke and traumatic brain injury, but lessons learned will guide new developments.
Researchers at UNC Chapel Hill used nuclear magnetic resonance spectroscopy to study the effects of crowded environments on protein shape. They found that intrinsically unstructured proteins exhibit a definite folded-up shape when inside cells, unlike their apparent lack of structure in water solutions.
Cosmologists suggest universe may collapse in 10-20 billion years due to dark energy, reversing the popular view of a runaway universe. The Stanford team's model predicts the universe will slow down and contract, leading to a cosmic 'big crunch',
A recent study by OHSU suggests that hormone replacement therapy (HRT) can lead to improved breast cancer detection and survival rates. The research found that HRT users had a 100% survival rate after six years, compared to an 87% survival rate for non-users.
Researchers found that invasive ants build shelters for mealybugs, allowing them to feed safely. The mealybugs produce a significant amount of honeydew, providing 32% of the daily energy for fire ant colonies.
Research suggests that diet is a second leading cause of cancer, accounting for approximately 30% of cancers in developed countries. A healthy weight, restricted alcohol consumption, and a balanced diet rich in fruits, vegetables, and cereals can help reduce cancer risk.
The study explores how older widowed women in Britain transition to becoming 'women alone', finding a new sense of confidence and self-sufficiency through personal growth and engaging in new activities.
Researchers found that beta-secretase activity is increased in Alzheimer's diseased brains, specifically in temporal and frontal cortex. This increase persists throughout the duration of the illness, making BACE a promising target for treatment, even late in the disease.
A University of Florida study found that married individuals, particularly whites, are less likely to recommit crimes. In contrast, unmarried men, including those from minority groups, are more likely to engage in criminal activity due to the lack of structured schedules and employment.
Researchers at Lawrence Livermore National Laboratory confirmed that waters migrating from the surface to the water table in drier regions can take many tens of thousands of years. These waters, which began their migration at the last ice age, hold a scientific and historical record of global climate change.
Researchers successfully immobilized an enzyme called organophosphorus hydrolase, nearly doubling its activity levels. The breakthrough could lead to the development of novel sensor and decontamination systems for homeland security and environmental protection.
A study by Nikola Pavletich and colleagues reveals that BRCA2 protein binds to damaged DNA, repairing it. This discovery sheds light on the mechanism of breast cancer development and opens new avenues for treatment strategies.
Despite a state budget crisis and terrorism, Virginia remains positive in its assessment of the state's qualities. Virginians report satisfaction with friendships, family relationships, education, medical care, retirement options, and vacations.
A new study published in Obstetrics and Gynecology found that oral contraceptive use during adolescence is not associated with weight gain or increased body fat. Researchers monitored 66 female participants, aged 16-21, for four years, tracking their blood lipid patterns and body composition.
The National Human Genome Research Institute (NHGRI) has upgraded the priority of cow, dog, Oxytricha trifallax, and Trichoplax genomes to high or moderate based on medical and biological opportunities. The genome sequences are expected to speed up studies of these agriculturally important animals and have medical benefits for dogs.
Scientists have unraveled the mystery of membrane fusion, a process crucial for gene therapy and drug delivery. By analyzing X-ray diffraction patterns, researchers revealed that membrane fusion begins with an hourglass-shaped structure called a stalk.
A new study reveals three distinct species of African elephants: savanna, forest, and west African. The west African population has been diverging for over two million years and is threatened with extinction due to human activities.
A Cornell University project explores the complex relationship between Kenyan small farmers, their communities, and the land they depend on. The research highlights the devastating effects of soil degradation, leading to reduced crop productivity and increased poverty. Understanding social and cultural factors is crucial in addressing ...
Head lice are becoming increasingly resistant to specialized shampoos, with 50-98% remaining after treatment. Researchers use artificial 'scalp' to study the pests on a genetic and molecular level, seeking alternative treatments.
Children's Hospital researchers estimate national costs associated with bicycle handlebar-related injuries, which can result in lengthy hospital stays and long-term disability. The study recommends adopting safer designs and educating parents on choosing and maintaining bicycles to minimize the risk of such injuries.
A home-based preschool program in South Carolina has shown significant improvement in disadvantaged children's school readiness and academic performance. The program, which provided twice-weekly visits to families from low-income backgrounds, resulted in higher test scores compared to the general population.
Researchers uncovered characteristics of faults that move backwards, contrary to conventional observations, and found the material within faults is significantly different than its surroundings. The study provides a new way to identify potentially active faults and better understand the earthquake process.
Researchers have discovered a key molecule involved in regulating the immune system that may contribute to stomach cancer. Mutations to this molecule, gp130, induced cellular changes reminiscent of early gastric cancer in mice, highlighting a potential new target for treatment.
Researchers identified 216 'stemness' genes that are active in embryonic, neural, and hematopoietic stem cells. These genes are involved in coping with stress, signaling, and self-renewal, and can aid in developing techniques to induce stem cells to differentiate into specific adult cells.
A recent clinical trial found that tamoxifen reduces the frequency of breast cancer by a third in women at increased risk. However, tamoxifen use also increases the risk of blood-clotting complications, which may contribute to higher death rates.
Researchers observe temporary structure during membrane fusion, forming hourglass-shaped stalk connecting two membranes. This discovery may lead to understanding of viral infection and designing new drug delivery methods.
Researchers at Princeton University identified a core set of genes responsible for regulating stem cell behavior and unique activities. The study also uncovered over 4,000 genes active in surrounding tissues that influence stem cell behavior.
Researchers found that using a mesh patch for large hiatal hernias results in no recurrence of the condition, marking a significant improvement over traditional surgical methods. This breakthrough study provides new hope for patients with large hiatal hernias, offering an effective and lower-risk treatment option.
Researchers at Memorial Sloan-Kettering Cancer Center have uncovered the function of the BRCA2 protein, which interacts directly with DNA to repair genetic damage. This new understanding sheds light on how mutations in the BRCA2 gene contribute to inherited breast and ovarian cancers.
Researchers at Purdue University have found that chlorine dioxide gas is highly effective in killing bacteria on food surfaces, particularly Listeria monocytogenes. The study showed significant reductions in bacterial populations on apple skin, stem cavity, and calyx using the gas.
Researchers found that benzene derivatives have higher neurotoxic potency than previously thought. The study suggests related aromatic chemicals may also damage the nervous system, with potential applications as a biological marker of exposure.
In Angola, displaced people turn to family members, neighbours, and church groups for advice and consolation in the form of conselho. This community-based approach emphasizes shared suffering and practical help over Western-style counseling. Local perspectives are crucial for culturally relevant psychosocial interventions.
The National Functional Genomics Project aims to track genetic changes in cancer to design more effective therapeutic agents and understand hereditary and environmental influences. Moffitt's expertise in translational research will accelerate the translation of molecular medicine into early detection and clinical treatment.
A randomized multicenter trial of 840 patients with severe heart attacks found no difference in mortality between pre-hospital fibrinolysis and emergency angioplasty. Despite this, experts advocate for early intervention with antiplatelet therapy and primary PTCA, regardless of hospital proximity.
Bipolar disorder is associated with high rates of substance abuse, with 60% of patients using stimulants. Dual-diagnosis patients require increased hospitalization and have poorer treatment response. Researchers are studying medications to reduce drug cravings and usage.
Researchers at Johns Hopkins Medicine have successfully created a biologic pacemaker using gene therapy in guinea pigs. The new pacemaker allows heart cells to regulate their own rhythm, potentially providing an alternative to traditional electronic pacemakers for patients at high risk of infection or with limited space for implantation.
Researchers from Leiden discovered that vitamins C and E can prevent breathing problems in patients after surgery by reducing the impact of sedatives and painkillers. The study found that stress and pain play a significant role in maintaining alertness, which may help counteract breathing issues.
A new soot filter for diesel engines has been developed, featuring a series of perforated ceramic foams that can absorb large quantities of ash before becoming blocked. The filter's design is based on studies of diesel particle structure and fractal geometry.
A recent terror warning highlights the potential danger of laptops and electronic devices on planes, sparking calls for improved security measures. Researchers like Uber advocate for airline monitoring systems to detect interfering signals inside aircraft cabins.