The study reveals that protein components in the post-synaptic density (PSD) move together in response to neural activity, with a significant percentage undergoing up-and-down regulation. The findings also suggest a high rate of PSD remodeling, with neurons replacing its content multiple times a day.
Researchers at Memorial Sloan-Kettering Cancer Center successfully eradicated cancer in mice using targeted immunotherapy with engineered human T cells. The study, published in Nature Medicine, demonstrates the first-in-vivo efficacy of adoptive immunotherapy with engineered human T cells in mice.
A team of scientists from the University of Wisconsin-Madison has developed methods for recombining DNA segments in human embryonic stem cells using homologous recombination. This technique allows for manipulating any part of the human genome to study gene function and mimic human diseases.
A host gene variant on chromosome 6 has been identified as making people more vulnerable to leprosy. Researchers used genome scanning to analyze DNA samples from nearly 100 families and confirmed the findings in an additional 200 families.