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Science News for May 7, 2003


Breakthrough in fight against infection misery

A team of researchers has developed a new method to prevent urinary catheter infections, which affects millions worldwide. By using a mild triclosan solution to inflate the balloon holding the catheter, they have successfully eliminated bacterial growth and blockages, offering a promising solution to this long-standing problem.

SourceCardiff University·JournalThe Lancet·DateMay 7, 2003

Genetic regulator of lifespan identified

The PNC1 protein regulates nicotinamide, a form of vitamin B3, which acts as an inhibitor of Sir2, a founding member of proteins controlling cell survival and lifespan. This discovery suggests that lifespan is controlled by an active genetic program in cells, potentially boostable.

SourceHarvard Medical School·JournalNature·DateMay 7, 2003

Gene enhances prefrontal function at a price

A study found that a specific gene variant affects prefrontal brain function and response to amphetamine. People with the val/val variant had reduced prefrontal dopamine activity and less efficient information processing, while those with met/met had more efficient function but also faced cognitive decline when challenged.

SourceNIH/National Institute of Mental Health·JournalProceedings of the National Academy of Sciences·DateMay 7, 2003

UCR scientists modify existing chemical scrubber to environmentally friendly, all-natural filter

Scientists at UC Riverside have modified an existing full-scale chemical scrubber to a biological trickling filter, achieving treatment rates comparable to chemical scrubbers. The conversion resulted in annual savings of $30,000 per year, with potential for widespread adoption and significant cost benefits.

SourceUniversity of California - Riverside·JournalProceedings of the National Academy of Sciences·DateMay 7, 2003

Dartmouth researchers find two circadian clocks in the same plant tissue

Researchers found that Arabidopsis plants respond differently to light and temperature signals, with one gene focused on photosynthesis and the other sensitive to temperature. This discovery suggests that plants have multiple internal clocks operating within a single tissue, allowing them to make critical decisions about flowering.

SourceDartmouth College·JournalProceedings of the National Academy of Sciences·DateMay 7, 2003

Success of chemotherapy tied to genetics

Researchers at McGill University discovered a genetic mutation, MTHFR variant, that predicts better response to fluoropyrimidine-based chemotherapy in advanced colorectal cancer patients. The study found 26 out of 43 patients with the variant responded well to chemotherapy.

SourceMcGill University·JournalClinical Cancer Research·DateMay 7, 2003