A study published in Radiology found that MRI can accurately detect bone invasion by soft-tissue sarcomas, with a sensitivity and specificity of 100% and 93%, respectively. This accuracy enables radiologists to confidently evaluate MR results for bone involvement, previously reserved for soft tissue involvement.
Researchers have identified a molecular understanding of the abnormal proteins causing retinitis pigmentosa, a degenerative eye disease. They will now focus on designing effective drugs to delay disease progression by stabilizing the mutated rhodopsin protein.
A recent study of early-stage breast cancer patients found that tamoxifen is effective in reducing recurrence and mortality regardless of body mass index. However, obesity was linked to increased risks of second cancers and all-cause mortality.
A new dual-energy, contrast-enhanced digital subtraction mammography technique has shown promising results in revealing hard-to-detect breast cancers. The study found that the technique was able to identify cancerous tumors in 13 out of 26 patients, with accuracy rates similar to those achieved by breast magnetic resonance imaging (MRI).
A recent study by Henry Ford Health found a significant link between early antibiotic use in children and an increased risk of developing allergies and asthma. The study followed 448 children from birth to seven years and found that those who received antibiotics in the first six months were more likely to develop these conditions.
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded grants to fund the construction of six biosafety laboratories, including three NBLs and three RBLs. The new labs will provide a safe environment for scientists to conduct critical research on infectious diseases and bioterrorism.
The Tylenol Scholarship is one of the largest merit scholarship programs in the United States for all health-related studies. Since its inception in 1991, more than $6 million in scholarship grants have been awarded to over 5,000 students by McNeil Consumer & Specialty Pharmaceuticals.
A large-scale study from Massachusetts General Hospital finds radiofrequency ablation (RFA) to be the most effective treatment for osteoid osteoma, a type of benign bone tumor. RFA offers a high success rate and low complication rate, making it an attractive alternative to traditional surgery and medication.
Researchers found five SNPs associated with differences in BMI, waist size, and skinfold totals, highlighting the interplay between genetics, SES, and family history of cardiovascular disease. The study suggests that a combination of genetic makeup and behavioral environment is responsible for obesity development
Researchers found that variations in genes related to serotonin receptors and liver enzyme CYP2D6 impact antidepressant efficacy and side effects. The study suggests personalized treatment approaches based on individual genetic profiles.
Researchers at the Office of Naval Research created a national study to understand and predict abrupt wing stall (AWS) in aircraft. They developed new tools and procedures to assess an aircraft's susceptibility to AWS, which can be used to screen new wing designs earlier in their development phase.
Researchers found that adolescents with impaired stress-induced pressure natriuresis showed increased urinary creatine levels and higher blood pressure after stress, indicating excessive kidney workload. This response pattern may lead to early development of renal disease.
A study published in Journal of Personality and Social Psychology found that creative individuals have low levels of latent inhibition, a process that filters out irrelevant information. This allows them to remain open to new possibilities, potentially leading to original thinking and creative accomplishment.
This tip sheet explores the impact of continuity of care on patient outcomes and healthcare costs. Research suggests that provider continuity is associated with lower total healthcare costs, but not necessarily improved quality of care for patients with chronic conditions like diabetes.
Researchers investigated chronic pain management through surveys, questionnaires, and studies. The results highlighted the importance of pain treatment outcomes, associations with health-risk behaviors, and post-traumatic stress disorder relationships. Additionally, a new exercise program improved arm and hand recovery after stroke.
Researchers found increased COX-2 protein expression and changes in TXA2 and PGE2 levels in the Obese Zucker rat, which led to kidney damage. The study suggests that COX-2 inhibitors may be beneficial for preventing renal damage in obesity-related type II diabetes.
A study by John Bound found that health conditions limit work among all workers, but disproportionately affect minorities. Education plays a crucial role in income disparity, accounting for 52-84% of the gap between racial groups.
The CBLAST project aims to provide more accurate predictions of hurricane intensity, landfall, and storm surge using new data-collection instruments and computer models. This research will help save lives and reduce economic losses for citizens and the Navy.
A new study finds that stress-induced salt sensitivity and increased blood pressure load contribute to racial differences in hypertension prevalence. The research suggests that these factors may help explain the higher incidence of hypertension among African-Americans, a long-standing public health concern.
Researchers investigate how La Jolla and Scripps Canyons near San Diego impact waves, currents, and beaches. The study uses a multidisciplinary approach with sensors, aircraft, and autonomous underwater vehicles to gather data on the dynamic nearshore environment.
The IBISCA project aims to understand the vertical stratification of insects throughout the dark understory and emergent canopy of Panama's tropical forest. Using advanced technologies, including a canopy crane, raft, bubble, and treehouse, researchers will collect samples and data on arthropods and other organisms.
Researchers will develop mathematical models to better understand coral bleaching and predict future changes. Localized warming of the world's oceans is causing thermal stress on coral reefs, leading to mass bleaching and ecosystem decline.
Researchers developed a systematic approach to inhibit 1,000 Drosophila genes and observed changes in cell morphology. By clustering genes by their effects, they assigned functions to 50 previously uncharacterized genes, shedding light on cellular processes.
A manual, low-tech method for 2nd trimester abortions has been deemed safe and effective. The study, conducted at Johns Hopkins Medicine, compared the procedure to electric vacuum aspiration and found no significant differences in complications or procedure time.
A recent study found that men aged 55-74 who received regular prostate cancer screenings every 4 years had a low rate of interval cancers. The screening procedure showed an 85.5% high sensitivity rate for detecting cancers, suggesting that very few aggressive prostate cancers escape screening.
A new study found that adjuvant chemotherapy did not improve survival rates for patients with surgically removed non-small-cell lung cancer. Additionally, a study on selenium supplementation revealed that it may increase the risk of squamous cell carcinoma and total nonmelanoma skin cancer in individuals at high risk.
Researchers used a new microdialysis technique to study amyloid-beta levels in interstitial fluid and cerebrospinal fluid of mice with Alzheimer's-like changes. They found that ABeta42 levels decrease in cerebrospinal fluid while AB40 increases, suggesting a shift in how the molecule is moved between compartments.
Researchers found that high-fat diet causes downregulation of CYP4A and CYP2C23 enzymes in renal tubules, leading to increased sodium reabsorption and elevated blood pressure. This study highlights the importance of eicosanoid synthesis in regulating renal function and blood pressure.
A new animal study found that PKC may contribute to reduced erectile response in diabetic-obese Zucker rats. The researchers observed increased protein expression of PKC isozymes and Rho-kinase b in the corpus cavernosum, suggesting a role for PKC in vasoconstriction and reduced erectile function.
A new study has identified specific molecules whose genetic regulation is altered during aging, contributing to vascular remodeling. The study found that inflammatory-associated adhesion molecules ICAM-1 and VCAM-1 had significantly increased expression at older ages.
A study published by the University of Pittsburgh found that hormone therapy has no benefit to postmenopausal women, even those at high risk of fracture. The research suggests that estrogen plus progestin increases bone mineral density but does not outweigh risks associated with breast cancer and heart disease.
Researchers found that 12-month-old infants looked longer at the ball approaching a helpful square, indicating they differentiated between the movies. This suggests that infants have ideas about what type of action would be more likely for the ball given its previous interactions.
Researchers found that common raven populations in the western Mojave Desert have exploded by 1,500 percent, posing a significant threat to young desert tortoises. The study used artificial baits to assess risk of predation and mapped areas with high predation risk, highlighting the importance of safe refuges for tortoises.
Researchers have developed a modified smallpox vaccine that is expected to be identical in effectiveness to the current vaccine but treatable for rare complications. The new vaccine will use genes to make the virus susceptible to common drugs, allowing doctors to effectively treat severe reactions.
Four research organizations will receive funding to develop promising HIV vaccine candidates using DNA vaccines, virus vector vaccines, subunit vaccines, and virus-like particle vaccines. Researchers aim to induce strong cellular and antibody immune responses in animal models.
Researchers found that combining anti-angiogenic and Hsp90 inhibitor drugs completely inhibited tumor growth in Id deficient mice, but had limited effect in mice with normal Id function. The study suggests a new approach for treating advanced breast cancer.
A new treatment approach uses a Trojan Horse technique to deliver a radioactive isotope into breast cancer cells, slowing tumour growth. The therapy combines EGF with Indium-111, exploiting the natural uptake of EGF by breast cancer cells.
A University of Toronto professor has created a way to turn hemp into strong and lightweight biocomposites. These materials can be used in various applications such as automotive interior parts, structural buildings, sports equipment, and even medical devices like cardiac devices and blood bags.
The NIAID Biodefense Research Agenda has made significant strides in developing vaccines, treatments, and diagnostics for bioterror agents. The Institute has expanded partnerships with industry and academia to accelerate research and development of countermeasures.
Researchers have identified over 2,700 genes with unusual activity in people with scleroderma, a mysterious skin disease. The study's findings suggest the disease is systemic, not confined to visible skin patches, and may lead to improved diagnosis and targeted treatment options.
A study by Penn State researchers found that employer understanding of the Marine Corps experience is crucial in seeing its value, with those who comprehend core values and life skills leading to higher salary offers. However, a majority of employers lack clear understanding, resulting in no difference being seen between hiring civilia...
The Center for Environmental and Biological Chemistry (CEBC) will focus on developing greener chemical processes, including catalysts for cleaner solvents. Researchers will work with industry partners to create more efficient reactors and reduce waste, aiming to improve the quality of life through cleaner chemicals.
Researchers found that middle-aged individuals with high blood pressure perform slower in certain tasks compared to older adults with similar blood pressure levels. Age-related decline in cognitive performance was not accelerated by high blood pressure, but rather associated with overall difficulty of the task.
National Institute of Standards and Technology (NIST) researchers have developed a new metal-stamping test station with an X-ray stress measurement system. This equipment enables detailed maps of stresses and strains as sheets of steel and other metals are punched, stretched or otherwise shaped.
A study found that PET scans can detect activation of lymph nodes in HIV-infected individuals, suggesting potential targets for treatment. Researchers propose using PET scans to locate active nodes and target them with radiation or removal.
Researchers aim to create a scalable, secure, and economical network with two-way symmetric data communications service at 100 megabits per second. The project will explore fundamental innovations in network design and management to support applications not yet envisioned.
Researchers at UCSD investigate human dietary absorption of a cell-surface molecular sugar called N-glycolylneuraminic acid (Neu5Gc), found in red meat. The study reveals that people absorb and metabolize small amounts of Neu5Gc, triggering an immune response.
Girls developing early are more likely to be involved in delinquency due to their relationships with friends, who may be already involved in delinquent behaviors. Dating also plays a significant role, as early-developing girls are more likely to have romantic relationships and engage in minor delinquencies.
Researchers have identified a novel treatment for polycystic kidney disease (PKD) by targeting a specific receptor responsible for cyst development. The treatment, OPC31260, shows promise as a potential therapy for conditions like heart and liver failure.
The study found that nearly 68% of patients who received antidepressant treatment were alive after nine years, compared to about 36% of those who received placebo. The researchers believe antidepressants may provide protective effects by improving recovery and reducing mortality in stroke patients.
Researchers at University of Wisconsin-Madison identify a receptor for botulinum neurotoxin B, allowing for improved medical uses and prevention against biological threats. The discovery enables the development of antidotes and protective agents to neutralize the toxin.
A new analytical technique allows archaeologists to accurately date pottery and associated artifacts, resolving issues with organic material dating. The method involves extracting lipids from pottery fragments and radiocarbon dating them, providing a more reliable way to classify archaeological sites.
A study by Professor Nick Mount reveals how Canadian writers who emigrated to the US in the 19th century formed expatriate communities that helped promote and publish their work. These communities provided valuable networking opportunities, enabling many Canadians to achieve literary success and make a living from writing.
Researchers at UCSD identified a novel gene called Nxf1 that restores function to mutated genes by increasing normal product production, alleviating abnormalities in mouse mutations. This discovery offers hope for controlling human disorders caused by retrovirus insertion mutations.
A global physician survey found that six in ten doctors believe men are more likely to die from stroke than women, despite women being 11% more likely to die from the condition. The study highlights the importance of addressing hypertension as a major risk factor for strokes and improving awareness among women about their risk factors.
Researchers at NIST are studying how different factors affect fuel cell efficiency, including electrical and heating demands, temperatures, humidity, and power systems. The goal is to develop performance ratings that can help consumers understand the financial costs and benefits of fuel cells in various geographic and climate conditions.
Researchers at Johns Hopkins University have developed tiny plastic particles that can release medicine over a prescribed period, without triggering an immune response. The particles are designed to dissolve slowly in the body and cross the mucus lining of air passages, reaching their target cells underneath.
Researchers developed a new method combining atomic force and scanning capacitance microscopes to measure semiconductor switching speeds, enabling quick scanning of wafers for defects. This technique has the potential to determine if missing atoms in semiconductors slow down electrical charge movement.
Florida Institute of Technology scientist receives three-year grant to study high-energy proton-proton collisions and fundamental questions of nature. The grant is part of the CMS experiment at CERN, a large international collaboration involving over 1,850 scientists from 34 countries.
Research reveals early Andean cultures were advanced technologically, polluting the atmosphere with heavy metals and facing climate change challenges. The study suggests that several thousand tons of silver were produced in pre-Incan times, but most likely recycled or exported.