Scientists have created a comprehensive map of brain genes that regulate brain development, linking specific genes to specific brain locations. The Mahoney Transcription Factor Atlas will aid researchers in studying brain tumors and other disorders.
Researchers at Dana-Farber Cancer Institute found that the loss of hair color is caused by the gradual dying off of adult stem cells, which become depleted and make errors. This discovery may lead to a better understanding of the underlying mechanism of graying and potentially inform treatment for malignant melanoma.
A study found that people use different strategies to complete a jigsaw puzzle, which can increase competition and conflict when collaborating with others. The researchers identified two main approaches: 'border obsessives' who focus on completing the border first, and 'opportunistic' puzzlers who take a more creative approach.
Researchers found that male songbirds who shed their feathers too late may have duller, less colorful plumage, which could disadvantage them in attracting mates. The study, published in Science, used stable hydrogen isotopes and spectrometry to analyze feather color and carotenoid concentrations.
A new driving regulation in Japan allows people with epilepsy to obtain a driver's license after a seizure-free period of two years. The survey results highlighted the need for cooperation between authorities and the Japanese Epilepsy Society to further amend regulations and educate the public, patients, and professionals.
Research found lesions on sperm whale bones increase with age and size, suggesting chronic decompression damage. Nitrogen gas bubbles from sonar or seismic survey guns may cause acute problems in whales.
Researchers discovered a link between brain activity and abnormal heart rhythms during stressful events, particularly in people with pre-existing heart disease. The study suggests that uneven brain signals can disrupt heart function, leading to potentially fatal arrhythmias.
The UGA/Penn team aims to develop a single-access point for genomic and related information about Apicomplexa parasites, enabling accelerated vaccine, diagnostic, and therapeutic development. The database will link existing databases for Plasmodium species, Toxoplasma gondii, and Cryptosporidum parvum.
Enterococcus faecalis uses a Sonar-like system to detect human blood cells and produce a toxin in response, providing a potential mechanism for developing new antibiotic treatments. This discovery could also be adapted to help the aging population cope with vision loss.
Researchers found that beta-arrestin2 activates the hedgehog signaling pathway, which can lead to cancerous tumors. The study suggests potential new drugs to block tumor growth by disrupting beta-arrestin2's function.
Research suggests that changes in gut microflora can intensify immune reactions to common allergens, increasing the risk of chronic allergies or asthma. A mouse model study found that antibiotic treatment led to an overzealous allergic response in the lung.
Researchers found that modern snails began edge-drilling their prey when competing for food with others, but returned to slow wall drilling when separated. This suggests that the severe extinction event ended high competition levels in the ocean, which have not fully recovered since.
Women with breast implants after mastectomy have a lower mortality rate from breast cancer compared to those without implants, suggesting that breast implants may improve survival. The study of over 4,000 women found that implant recipients had a 12.4% mortality rate, half that of non-implant recipients.
Researchers discovered a jumping gene called Hermes, which creates changes in DNA similar to those created by the process behind antigen recognition. This discovery provides evidence that genetic processes behind antigen diversity may have evolved from the activity of a jumping gene.
A newly discovered civilization in Peru's Norte Chico region thrived 5000 years ago, featuring monumental architecture and a complex economy. The finding sheds new light on the development of complex societies, challenging previous assumptions about early civilizations.
The National Evolutionary Synthesis Center (NESCent) has been established in Durham, North Carolina, with a $15 million grant from the National Science Foundation. The center aims to unify the biological sciences by promoting cross-disciplinary studies and synthesizing evolutionary knowledge for policymakers, educators, and society.
The US Department of Energy has fulfilled its commitment to sequence the human genome, publishing data on Chromosome 16. The completed chromosome includes 880 genes linked to various diseases, such as breast and prostate cancer, Crohn's disease, and adult polycystic kidney disease.
HydroGlobe's patented water-filtration technologies will be licensed to Graver Technologies, treating potable water supplies at home and municipal levels worldwide. Stevens President Harold J. Raveché validates the acquisition as a major recognition of pioneering work in environmental technology innovation.
The Wide Field Camera (WFCAM) is the world's most powerful infrared survey camera, detecting objects one hundred times fainter than existing surveys. It has captured stunning images of the Orion nebula, revealing thousands of young stars and dramatic clouds of gas and dust.
At the University of Rochester Medical Center, a team of nurses led by Diane O'Brien and John Treanor developed a system to inoculate over 200 volunteers with an experimental flu vaccine. The study aimed to assess the safety and effectiveness of the vaccine in preventing another flu vaccine shortage.
The invention uses protein-DNA chimeras to detect and count small numbers of molecules, offering exquisite sensitivity and dynamic range. Methods based on these molecules are designed to work with existing PCR machines, making them useful for human disease diagnosis, environmental monitoring, and pathogen detection.
Professor Xiaolian Gao's research develops a technology to mass-produce multiple genes on a single chip, reducing costs and time factors by 100 times. This breakthrough has the potential to create complete functioning organisms, produce energy, neutralize toxins and make drugs.
Researchers found that increased solar radiation affects calcium and sodium deposition in Antarctica, indicating a link between solar activity and climate. This discovery sheds light on the Earth's climate system without accounting for human impacts.
Researchers used somatic hypermutation to evolve a red fluorescent protein with improved stability and color emission properties. The new protein, mPlum, was created by allowing B cells to mutate the gene at a rate of roughly a million times that of the genome. This process enabled the production of multiple mutations in a single cycle.
A new stool DNA test has been found to detect a significant proportion of colorectal cancers, potentially overcoming barriers to screening among unwilling individuals. The test, which analyzes tumor-specific DNA, detected 52% of cancers in average-risk asymptomatic individuals.
Scientists have developed a range of new fluorescent proteins with unique colors, allowing them to track the effects of multiple genetic alterations in a single cell. These monomeric proteins retain fluorescent properties while being less toxic than their multimeric counterparts, enabling precise cellular analysis.
Archaeologists have confirmed the existence of a complex society in South America dating back over 5,000 years. The inland culture, based on agriculture, featured monumental architecture and sophisticated social hierarchies.
A team of researchers from Duke University has successfully used micromanipulation to study the separation of sister chromatids in cell division. Their experiments revealed that chromatids are initially attached but then separate at their centers, with linkages playing a crucial role in their separation.
Male crickets fed high protein diets engage in more sexual calling and die sooner than those on low protein diets. This is because they spend extra resources on mating behavior, shortening their lifespan. In contrast, males on low protein diets tend to delay calling until later in life, maintaining their body weight for longer.
The McMaster researchers developed a detailed bleeding history questionnaire to discriminate between patients with QPD and those without. The tool helps identify higher likelihoods of bleeding that leads to lifestyle changes, bruises or bleeding in joints, providing valuable clues for doctors diagnosing the condition.
A study analyzing cancer death records from 1989-2000 found no correlation between cancer mortality and holiday events like Christmas or birthdays. However, it did reveal a slight increase in cancer deaths among certain populations, such as black Americans before Thanksgiving and white women on their birthdays.
Scientists studying prion diseases in mice found that preventing cell death does not stop the progression of neurological symptoms. Damage to synapses, critical for nerve cell communication, is instead linked to the disease.
A study by Johns Hopkins Medicine found that pulsatile lavage equipment was the cause of an Acinetobacter baumannii outbreak, infecting 11 patients. The investigation led to changes in hospital procedures, including wearing masks and gloves during procedures and using private treatment rooms.
A study examining genetic factors in lung cancer found increased risks for first-, second-, and third-degree relatives of patients with lung cancer. The risk was stronger for early-onset disease, suggesting a possible genetic component beyond environmental factors.
Researchers found a significant increase in obesity (12% of men, 11% of women) and drinking (almost doubled in women with highest qualifications) among UK youth since the 1940s. Additionally, depression and anxiety rates have risen, with modern mothers less likely to breastfeed their children.
A study of 10,591 Taiwanese residents found that those exposed to high levels of arsenic in their drinking water had a 3.29 times increased risk of developing lung cancer. Cigarette smoking further exacerbated this risk, particularly among non-smokers and those with lower arsenic exposure.
Researchers analyzed death certificate data from Ohio between 1989-2000 and found no significant dip or peak in cancer deaths around Christmas, Thanksgiving, or birthdays. Women dying of cancer were more likely to die during the week before their birthday compared to men.
Nanotubes form along atomic steps due to iron nanoparticles' attraction to local fields created by the steps. The orientation and form of these steps can be controlled, enabling the production of different nanowire arrangements.
Researchers found that increasing one skill can significantly impact others, with some activities dropping and others increasing in levels. The primary function of the enzymes remained largely unchanged despite changes in other promiscuous traits.
A study by Johns Hopkins researchers found that doctors talk more to white patients than black patients during medical visits, leading to less engagement and participation. This difference in communication style contributes to health disparities among African-American patients.
Pharmacogenomics has the potential to improve treatment successes and reduce adverse reactions by targeting specific drugs at specific patients. The industry is expected to bear a larger share of costs associated with drug-treatment failures as well-targeted therapies become more commonplace.
Researchers at UCL found that brain activity increases in areas known as the 'mirror system' when experts view movements they've been trained to perform, compared to non-experts. This fine-tuned system may enable professionals to simulate skills without moving and maintain movement ability despite injury.
The St. Jude team determined the shape of CbpA, a large protein used by Streptococcus pneumoniae bacteria to invade human cells. This discovery will guide researchers in developing a new vaccine that can trigger production of antibodies against the CbpA protein.
A team of researchers led by Gary Gilliland discovered that certain leukemia oncogenes can reactivate self-renewal programs in mature white blood cells. This finding has significant implications for understanding and treating chronic myeloid leukemia, a disease fueled by a small population of cancer stem cells.
Researchers found that women experiencing menopause have reduced estrogen sensitivity in their brains, leading to increased hot flashes and night sweats. The study suggests that this insensitivity may contribute to menopause-related symptoms.
Researchers found that dreams up to a week after a memorable emotional event often reflect problem resolution and positive emotions. This suggests that dreams can serve as a treatment for working through personal difficulties.
A study found that acute eosinophilic pneumonia (AEP) was diagnosed in 18 US military personnel deployed to Iraq, with a high incidence rate of 9.1 per 100,000 person-years. All patients reported significant exposure to fine airborne sand or dust and used tobacco, but no common source exposure was identified.
Researchers tested devices outside of the body and found no interference, but warn that technology advances require continual testing for clinical safety.
A new technique developed by the University of Toronto team enables accurate measurements of individual exons that make up different mRNAs, opening doors to understanding more about some diseases. This process, known as alternative splicing, is a cellular process that acquires the ability to control genetic messages.
Researchers study the impact of hurricanes on coral reefs in South Florida, finding a temporary removal of invasive seaweed. However, experts caution that without addressing nutrient pollution and its root causes, reefs will remain vulnerable to similar problems.
A study found that only 12% of jails continued methadone treatments for withdrawal, while 48% failed to provide appropriate detoxification methods. The lack of coordination between jails and community clinics is a major concern.
The Journal of Dental Research (JDR) is now featuring manuscripts from Critical Reviews in Oral Biology & Medicine, enhancing its content and Scientific Impact Factor. The journal will also be made freely available online after 12 months.
A large study of 188 women found that nearly 55% with minimal unwanted hair growth had an androgen excess disorder, primarily polycystic ovary syndrome (PCOS). Women with PCOS often struggle with menstrual irregularities, skin problems, and excess weight.
Ohio State University engineers created software that enhances a speaker's face and gesturing hands without increasing bandwidth, resulting in clearer visuals for users. The technology uses video recordings of TV personalities like Jay Leno to test the software, showing improved results.
Researchers found that Paxceed increased protein travel down spinal axons and improved microtubule density in tau transgenic mice. The drug also reduced motor impairment in the mice.
The guidelines provide recommendations for screening and management of late effects in pediatric cancer survivors, aiming to improve adult quality of life. The report authors anticipate that widespread use will help researchers determine the efficacy of screening survivors to reduce medical complications and death.
A study found that home-based treatment for moderate to severe chronic hand dermatitis was as effective as hospital-based treatment in improving symptoms. Patients treating themselves at home had a similar decrease in hand eczema scores and maintained the effect during an eight-week follow-up period.
A recent study published in Archives of Surgery found that patients with abdominal trauma are at high risk of developing intra-abdominal infections following surgery. The likelihood of infection increased with more severe wounds, contamination of the abdominal cavity, and admission to the intensive care unit.
Researchers at Boston University analyzed heartbeat data from five healthy volunteers to understand the impact of circadian cycles on cardiac rhythms. The study found that the internal body clock influences cardiac fluctuations, with values showing a strong correlation when considering the entire 28-hour cycle.
Researchers found that old T cells weaken the immune system in older mice, causing impaired B cell activation and antibody production. However, infusing young T cells into old mice restored B cell function, suggesting a key role for helper T cells in maintaining immune capacity with age.