A 12-week study found that combining sertraline and CBT was more effective than treatment with just one or the other in reducing symptoms of obsessive compulsive disorder (OCD) in adolescents. CBT alone was also shown to be effective, particularly at the University of Pennsylvania site.
A new study finds that combining Pegasys with ribavirin reduces hepatitis C viral levels more effectively than Peg-Intron, a promising development in treating the virus. The study's lead investigator hopes that the findings will inform the design of better drugs to combat the infection.
A study of nearly 400 African-American patients found that weight-based REBETOL dosing with PEG-INTRON improved viral clearance and reduced relapse rates compared to a flat dose. The treatment showed promise in improving outcomes for this patient population, which has historically had lower response rates to hepatitis C therapy.
A new study reveals that stress activates the mania-linked enzyme PKC, leading to impaired cognitive functions in the prefrontal cortex and reduced memory-related cell firing. Inhibiting PKC may offer a fast-acting treatment for mania, with potential benefits for patients seeking emergency room care.
The American Geosciences Institute announced winners of the Earth Science Week contest, showcasing artistic talents in visual arts, essay writing, and photography. The contests aimed to increase public awareness of geology and the earth sciences.
Researchers at the University of Pennsylvania School of Medicine have found a gene-silencing technique that induces cell death in drug-resistant CML cells. The technique targets the Lyn kinase enzyme, which is essential for cancerous blood cells to survive and grow.
A new study by Professor Faye Mishna explores the complexities surrounding bullying, finding that children's perspectives often differ from those of parents and educators. The research highlights the importance of validating a child's distress even if the situation is not considered bullying.
Researchers have discovered that actin acts as a binding protein in the nucleus, recruiting other proteins to facilitate DNA transcription. This process is crucial for cellular activity and understanding its dysregulation is essential for developing new treatments for diseases like cancer.
FOSRENOL effectively controls hyperphosphatemia, a leading cause of renal osteodystrophy and bone pain in ESRD patients. Long-term use maintains bone health status without worsening bone status, unlike aluminum-based phosphate binders.
Researchers analyzed a sample from Gabon's natural nuclear chain reaction site and found how the reactor operated in a 30-minute cycle. The study also revealed the role of alumophosphate as the system's waste absorber, providing insights into safer nuclear reactor operations.
Researchers have developed blood cells without animal serum, paving the way for potential human applications. The new method uses specific growth factors to guide cell differentiation, avoiding contamination risks associated with animal serum.
A study of 806 women with early stage breast cancer found that regular physical activity significantly reduced the risk of weight gain and improved breast cancer prognosis. Physical activity was assessed during an in-person interview as part of the Health, Eating, Activity and Lifestyle (HEAL) study.
Researchers found evidence that HIV co-opts human enzyme DDX3 to transport its genetic material out of the cell nucleus. The discovery provides an attractive target for drug development and could lead to a new type of HIV drug that blocks viral replication without causing harm to human cells.
Researchers from the Collaborative Mercury Research Network (COMERN) are conducting a unique experiment to test whether old-fashioned tea can prevent mercury absorption. In this study, participants will eat local Lake Winnipeg fish with or without black tea for three days, and provide blood samples to track mercury levels.
A recent Canadian study found that workplace smoking bans lead to a significant reduction in daily cigarette consumption among smokers, with an average drop of 15.4 cigarettes per day. The ban has been shown to increase the likelihood of smokers cutting down or quitting altogether.
Apolipoprotein E is responsible for converting harmless amyloid-beta protein into toxic filamentous amyloid, a major hallmark of Alzheimer's disease. Mice with the gene showed memory deficits only when it was present.
A new study suggests that the DASH diet's numerous fruits, vegetables, and whole grains contribute significantly to its health benefits. The diet's high intake of phytochemicals may help protect against various chronic diseases, including cancer, heart disease, and other health conditions.
Researchers found that patients who were diagnosed with non-cardiac chest pain and then had heart events were older, more likely to be men, and had high-risk features such as high cholesterol. Further evaluation should be considered for these patients, says lead researcher Chadwick Miller.
Astronomers confirm that the Virgo Cluster of galaxies is a highly non-uniform structure consisting of several subunits. The cluster's formation history can be studied using planetary nebulae stars, which trace the masses within the region. These findings provide new insights into the dynamic evolution of galaxy clusters.