A study by Thomas Stamey and colleagues found that the correlation between PSA levels and prostate cancer severity has decreased over time, making the test less useful for early detection. Instead, they recommend a yearly digital rectal exam for men over 50.
A recent study found that sex and drug use behaviors are associated with higher levels of depression, suicidal thoughts, and suicide attempts among teenagers. Girls who engage in high-risk behaviors are more vulnerable to poor mental health than boys.
The 5-year project aims to determine which microbial proteins interact with human host cells, pointing the way to new drugs. Researchers will use advanced proteomics instruments to analyze these interactions, accelerating treatment development during outbreaks.
Researchers have developed a new dye that allows for direct visualization of activated proteins in living cells, enabling high-throughput drug screening. Cdc42, a key regulator of cell movement and proliferation, was visualized with the novel dye 'I-SO', which proved highly sensitive and required no protein over-expression.
Researchers found that growth hormone reduces STAT3 activation, modulates cellular apoptosis and proliferation, and improves weight gain in mice with colitis. The study suggests using growth hormone as a new therapeutic approach to improve growth and intestinal healing in IBD.
A new gene test can predict a child's risk of having an isolated cleft lip and palate, allowing parents to make informed decisions about future pregnancies. The test, based on distinct mutations in the IRF6 gene, has been shown to be effective in predicting the birth defect with approximately 12% accuracy.
Researchers at Texas A&M University found that blue marlin caught in the Gulf of Mexico contain 20-30 times the acceptable levels of mercury. The team aims to understand why mercury accumulates in pelagic fishes and how it affects human health.
Research conducted by Penny Gordon-Larsen found that excessive TV watching and a lack of safe outdoor spaces contribute to increased obesity risk in young black girls. The study, which included 51 interviews with girls aged 6-9 and their mothers, highlights the need for affordable and accessible opportunities for physical activity.
Researchers explore how prosthetic legs can be tailored to improve mobility and comfort for amputees. Studies examine the impact of different shoes, sock liners, and physical activities on residual limb soft tissue damage and overall health outcomes.
Scientists have successfully created a mouse lacking both MAO A and MAO B, revealing the combined actions of these enzymes in neurotransmitter regulation. This breakthrough may lead to new insights into anxiety- and stress-related disorders.
A government study estimated that nearly half a million medical device injuries occur each year, with falls while using wheelchairs and walkers being the most common recorded injury type. The study suggests that the actual number of injuries may be higher due to underreporting by healthcare providers.
A 73-year-old woman lost all dreaming and most brain functions following a stroke, but regained some dreaming function over time. Researchers found that the damaged area of her brain was involved in visual processing and emotions.
Researchers will study 120 patients with chronic and aggressive periodontitis to identify molecular basis of disease and develop targeted therapies. The goal is to reduce risk of periodontitis and improve treatment outcomes for the leading cause of adult tooth loss.
Dr. C. Ronald Kahn receives the award for his groundbreaking work on insulin signal transduction and its link to diseases like diabetes, Alzheimer's, and obesity.
Researchers at Baylor, MIT and Hebrew University have made significant progress in understanding the potential of combination therapy for Inflammatory Bowel Disease (IBD). Probiotics and commensal bacteria have been shown to modulate mucosal pro-inflammatory cytokine production and reduce symptoms in mice. Additionally, a new class of ...