Research suggests that cardiac arrest can cause structural changes in neurons, leading to memory deficits and behavioral changes. The study found that mice with a heart attack had difficulty learning new spatial tasks compared to healthy mice.
A collaboration between pharmaceutical manufacturers, healthcare agencies, and researchers led to a significant reduction in epoetin-associated pure red-cell aplasia. The incidence decreased by 83% after improvements were made in storage and handling of the drug.
A study published in the Journal of Clinical Oncology found that smokers have a higher risk of death, disease recurrence, and poorer survival rates compared to non-smokers with head and neck cancer. Researchers highlighted the importance of tobacco cessation and moderation of alcohol use to improve quality of life and survival.
The Illinois initiative aims to examine the biological effects of isoflavones on various bodily systems, including breast, brain and adipose tissues. Researchers will investigate the mechanisms at work between isoflavones and estrogen receptors to ensure safety and effectiveness in dietary supplements.
Researchers led by Harvard University's David R. Liu report a highly efficient system for reaction discovery using DNA-templated synthesis, allowing a single researcher to evaluate thousands of potential chemical reactions in just two days. The technique taps the unique assembly power of nucleic acids to address fundamental challenges ...
Mortality rates from injuries increased from 14.3 per 100,000 in 1960 to 42.3 per 100,000 in 1995, with males accounting for 88% of all injury deaths. Intentional injuries, such as stab wounds and homicides, contributed significantly to the rising death toll.
Researchers discovered that a type of plant TE called MULEs can capture and fuse rice gene fragments to create new genes and functions. This process, known as Pack-MULEs, may be an important mechanism for evolutionary change in plants.
Researchers validated five clusters of common withdrawal symptoms: headache, fatigue, dysphoric mood, difficulty concentrating, and flu-like symptoms. A stepwise approach can eliminate severe withdrawal symptoms by gradually reducing caffeine consumption.
Steve McKnight's research on gene regulation and the body's internal clock has led to discoveries that may help understand and treat insomnia and depression. The NIH Pioneer Award recognizes his innovative work in taking creative risks and achieving groundbreaking accomplishments.
Researchers led by Graham Bell discovered that increased carbon dioxide concentrations negatively impact algae growth, disproving the notion that plants absorb extra CO2. The study's findings have implications for all plant species, including agricultural ones, as fossil fuel emissions continue to rise.
A genetic predictive test identifies brain cancer patients who benefit from temozolomide, a targeted treatment. The study found a 46% survival rate for those with methylated MGMT promoter status.
Researchers have developed a method to stabilize and control the conductance state of single molecules using tailored intermolecular interactions. This breakthrough could lead to the development of molecular memory components with reduced power usage.
Researchers at UNC Health Care have identified a new mechanism by which Polycomb group proteins silence genes in cancer cells. The study found that ubiquitination of histone H2A is involved in this process, providing insight into gene expression regulation and potential targets for cancer treatment.
A Phase II study has shown that the drug imatinib is active against a rare type of cancer called DFSP, achieving complete control in eight out of ten patients. The research team believes molecular analysis can predict patient response to treatment based on genetic profiles.
Researchers from Imperial College London and UK universities successfully accelerated electron beams near the speed of light using laser-produced plasmas. This achievement paves the way for the development of smaller, more affordable particle accelerators that could be used in university laboratories.
Researchers discovered that the HMW1B protein forms a tetramer structure, unlike previously thought monomers, which creates an active pore for substance movement across cell membranes. This finding may lead to new targets for drugs to treat H. influenzae infection.
Researchers at Berkeley Lab develop a technique to channel laser-powered plasma waves, creating high-quality beams with particles over 80 MeV in energy. By optimizing plasma channel conditions and laser parameters, they achieve unprecedented beam intensity and suppress electron capture.
A review article suggests that age-associated executive function decline is due to frontal-striatal circuit changes, while medial temporal lobe memory system decline is more closely linked to Alzheimer's disease. Changes in white matter and neurotransmitter depletion also play a role.
Researchers at Ohio State University have identified five genes that can distinguish between papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC), two types of thyroid cancer with different behaviors and treatments. The study's findings may lead to a valuable diagnostic tool, improving patient outcomes.
Researchers created new memories in subjects and studied their recall in the laboratory using functional magnetic resonance imaging (fMRI). They found that recalling autobiographical memories activated similar brain areas as laboratory memories, but also distinct self-referential processing regions. This study provides new insights int...
A genetically engineered listeria bacteria-based vaccine has shown promising results in targeting metastatic cancer cells, inducing a strong innate and acquired immune response. The vaccine, aiming to target pancreatic and ovarian cancers, could potentially be used to prevent recurrence after surgery and chemotherapy.
A team from Pacific Northwest National Laboratory and Oregon Health & Science University has discovered a record number of proteins for the highly infectious human cytomegalovirus, doubling the previously identified amount. The study reveals that HCMV may express as many as 200 proteins at various points in its life cycle.
Researchers find that transposable elements, called Pack-MULEs, copy themselves prolifically and rearrange genes, making them newly discovered players in evolution. The discovery elevates these little-considered elements to potentially major players in the process of evolution.
Vascular tumor growth in children is linked to a protein called MCP-1 that recruits macrophages, stimulating angiogenesis and tumor growth. Anti-MCP-1 therapy may prevent tumor development and improve patient outcomes.
Two studies strengthen the connection between chronic kidney disease (CKD) and cardiovascular disease, showing that reduced kidney function increases the risk of death, heart disease, and hospitalization. Early detection and treatment are crucial to slow CKD progression and prevent these complications.
Scientists at the University of Illinois developed a new surface chemistry method to control defects in silicon wafers, extending the life of transistor technology. This technique uses nitrogen-containing gases to saturate dangling bonds and remove interstitials, resulting in shallower active regions and enhanced dopant activation.
The UK's productivity gap with the US, France, and Germany is substantial, driven by factors such as capital investment, skills, and innovation. Research suggests that improving competition, investing in physical and human capital, and enhancing management skills can help bridge the gap.
The Adult Learning@Home project found that e-learning is often associated with the same factors that determine school-leaving age, such as sex and socio-economic background. Despite universal access to ICTs, actual use is limited to just over half of the adult population.
A new system uses fuzzy logic to automatically detect room acoustics and speaker placement, providing each listener with their own personalized
Carbon nanotubes' electronic and mechanical properties are highly dependent on the presence of defects, which alter their vibrational modes and affect electrical conductivity and heat transport. The study demonstrates the importance of understanding these effects for optimizing nanoscale devices.
Scientists have successfully slowed down the group velocity of light in semiconductors, achieving speeds of about 6 miles per second. This breakthrough could lead to faster optical networks and higher performance communications, enabling applications like 3-D graphics transmission and high-resolution video conferencing.
The development of nanomedicines has led to significant advances in the diagnosis and treatment of disease. Thousands of patients are already benefiting from products used to treat conditions such as cancer, AIDS, and arthritis.
Parkinson's disease is often associated with depression, a condition that can significantly impact patients' lives. Research suggests that depression is part of the illness and not just a reaction to the disease.
The SNEWS system, an international collaboration of neutrino observatories, aims to provide astronomers with a prompt alert for galactic supernovas. This network can electronically compare data to increase scientists' confidence that a neutrino signal is really from a supernova.
A perfect lens could improve electronic circuitry, fiberoptic communications, and medical imaging, but mathematical analysis shows it is not feasible. Researchers used rigorous math to demonstrate that a perfect lens would struggle with the concept of negative refraction.
A computer program simulated how people who felt threatened would respond to a serial subtraction problem, showing a 25% decrease in performance speed. Increasing knowledge through instruction and practice, or continuously checking results to bolster confidence, can help individuals switch their pre-task appraisal from threatening to c...
Recent APS exercise research highlights significant findings in various areas, including reduced flu mortality and improved cardiovascular function. Studies on protein expression and skeletal muscle regeneration have also shed light on the mechanisms behind these processes.
A Princeton University study found that changes in U.S. forests caused by land use practices have increased the emission of smog-producing chemicals from trees, which may have worsened ozone pollution in some parts of the country. The study suggests that intensified tree farming and other land use changes have altered the mix of trees ...
Intraoperative MRI improved tumor removal by detecting additional tissue that needed to be removed, altering surgical strategy in 27.5% of cases. High-field MRI provides better image quality and reduced scan time, but its high cost is a limiting factor.
Researchers at Harvard University have found evidence of ancient grain milling and baking 23,000 years ago in present-day Israel. The discovery provides insight into the transition from foraging to food production, revealing that humans first developed technologies to process wild grains around 20,000 years ago.
A study by the University of Wales and the University of Exeter suggests that high levels of calcium intake combined with vigorous daily exercise are crucial for building and retaining bone mass in children. The researchers found that children should engage in at least 25-40 minutes of vigorous activity and consume at least 700-800 mil...
Researchers identified gene clusters that predict severe disease severity and location of atherosclerotic lesions in human aorta samples. The study used DNA microarray analysis to reveal 208 genes associated with severe disease and 28 genes related to disease location, showing promise for personalized medicine approaches.
The NSF-funded research centers will investigate decision-making strategies for addressing climate uncertainty, including water management and policy implications. The projects will integrate psychological insights with social sciences to develop tools for better understanding the impacts of climate change.
A survey of over 700 adults found that 50% of men and only 32% of women supported routine paternity testing. The difference in response remained consistent despite marital and income status. Researchers speculate that women may seek a father's genetic heritage or parental investment, but this practice is rare due to the potential risks.
The new guideline suggests tricyclic antidepressants, gabapentin, lidocaine skin patch, and opioids as effective in reducing pain from postherpetic neuralgia. However, the long-term effects of these treatments are not yet supported by sufficient data.
The Wisconsin team developed two assays for botulinum toxin, including a real-time test and a cell-based assay that can screen millions of chemicals. The new technology could lead to the development of drugs that act like a prophylactic to confer protection from botulinum poisoning.
Dartmouth Medical School emphasizes ongoing feedback and mentoring in its educational research environment. The school attributes its success to a supportive faculty culture and rigorous evaluation processes.
Researchers at Washington University in St. Louis found that genetically distinct populations of brown lizards (Anolis sagrei) introduced to five countries can be traced back to Florida. The study, which analyzed DNA from over 600 individuals, suggests that the Sunshine State is a key site for species migration.
Scientists at Indiana University and the EPA will study the circulation of polychlorinated biphenyls (PCBs) between the air and Great Lakes, aiming to inform new clean-up policies. Elevated PCB levels have led to fish consumption advisories for all five Great Lakes, with implications for human health.
A randomized controlled trial found that patients referred to an alcohol-health worker after visiting the emergency department consumed significantly less alcohol over six months. This intervention reduced reattendance at emergency departments by 0.5 visits on average per year.
The study found that rural counties had over 1.5 times the rate of gun suicides compared to urban counties, while urban areas experienced almost twice the gun homicide rate of rural counties. Gun suicides have outpaced gun homicides in the US, accounting for over half of all firearm deaths.
A three-month study found that patients with type 2 diabetes preferred the prefilled NovoLog(R) Mix 70/30 FlexPen(R) disposable pen due to its ease of use and flexibility. Patients who had never used insulin before reported significant benefits in perceived clinical efficacy.
Researchers at Temple University validated the c-myb gene as a potential cancer drug target by demonstrating its critical role in white blood cell formation. The study found that deleting the gene reduced cell proliferation and the risk of developing cancer, offering hope for future breast cancer treatments.
Scientists use Zoe, an autonomous solar-powered rover, to explore the Atacama Desert and test robotic capabilities. They aim to detect signatures of microbial life remotely, which will aid in future human missions to Mars.
Researchers found that chronic exposure to morphine makes nerve cells more sensitive to stress, leading to increased anxiety and disrupted sleep patterns. The study suggests that this sensitivity may play a role in the cycle of addiction that causes drug abusers to continue seeking drugs.
A study by University of Washington researchers finds that press coverage of lawsuits often portrays plaintiffs winning far more frequently than they do in reality. The distortion is attributed to a combination of factors, including corporate public relations campaigns and the tendency of news media to skim on scientific evidence.
Researchers have identified Foxa2 as a master gene controlling lung development and function at birth. The absence of Foxa2 leads to respiratory distress syndrome and death, highlighting its crucial role in stabilizing surfactant production.
Researchers discover two distinct COI barcodes in each of four species: solitary sandpiper, eastern meadowlark, marsh wren and warbling vireo. The findings indicate that these species should be split, confirming suspicions among taxonomists.
Over 30 years of follow-up, Vietnam veterans experienced a 7% higher death rate from external causes, including motor vehicle collisions, suicides, and homicides. This excess mortality was limited to the first five years after discharge, but also included higher mortality rates from unintentional poisonings and drug-related deaths.
A study found that black men aged 65+ were half as likely to be tested for prostate cancer as white men, highlighting racial disparities in healthcare access. Low screening rates among African American men may contribute to higher prostate cancer mortality rates.