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Science News for December 5, 2005


Brain enlargement may be characteristic of autism

Researchers found significant brain volume enlargement in children with autism, particularly in white and gray matter, which affects the cerebral cortex responsible for thought, perception, and memory. The study suggests that this enlargement may begin as late as the first year of life, during the postnatal period.

SourceJAMA Network·JournalArchives of General Psychiatry·DateDec 5, 2005

Personal fulfillment may motivate adolescents to be physically active

Adolescents cite personal fulfillment as strongest motivator for physical activity, with weight-based motivation and peer influence also playing a role. The study's findings suggest that emphasizing personal fulfillment could be an effective approach to increasing physical activity among all youth, regardless of risk status.

SourceJAMA Network·JournalArchives of Pediatrics and Adolescent Medicine·DateDec 5, 2005

Mathematician's insight helps unravel knotty problem

Shelly Harvey's discovery applies to a longstanding problem within knot theory, but its significance lies in the broader context of topology. The underlying structure she uncovered uses algebraic structures to describe similarities and differences between knotted shapes, offering a new approach to proving equivalency.

SourceRice University·JournalGeometry & Topology·DateDec 5, 2005

Preclinical study of a new brain tumor therapy

Researchers developed a treatment that targets glioblastoma cells using epidermal growth factor receptors (EGFR), eliminating tumors in mice implanted with human brain cancer cells. The therapy showed no evidence of recurrence and remained effective for over a year, offering new hope for GBM patients.

SourcePLOS·JournalPLOS Medicine·DateDec 5, 2005

Medical College of Wisconsin study

A randomized controlled trial of 275 uninsured Latino children found that community-based case management resulted in a significant increase in insured children, with 96% obtaining health insurance compared to 57% without case managers. The intervention also showed improved parental satisfaction and faster insurance enrollment.

SourceMedical College of Wisconsin·JournalPEDIATRICS·DateDec 5, 2005

Molecule links Down syndrome to Alzheimer's

Research suggests that adults with Down syndrome have higher concentrations of myo-inositol in the brain, leading to reduced cognitive ability and increased risk of early-onset Alzheimer's disease. The study aims to develop a new treatment approach by reducing myo-inositol levels in the brains of people with Down syndrome.

SourceKing's College London·JournalArchives of General Psychiatry·DateDec 5, 2005

Ethnic minorities and health research

A new study found that racial and ethnic minorities are just as willing, if not more willing, to participate in health research than non-Hispanic whites. However, they were less likely to be invited to participate in these studies, highlighting the need for improved access and inclusivity.

SourcePLOS·JournalPLOS Medicine·DateDec 5, 2005

A leap forward in understanding cholera

Researchers developed a new cholera modeling approach that better explains past epidemics, suggesting human-to-human transmission is crucial for outbreak dynamics. The model incorporates the hyperinfectious state of the bacteria, which becomes more infectious when passing through a human host.

SourcePLOS·JournalPLOS Medicine·DateDec 5, 2005

Sooner is better with cochlear implants, Stanford scientist shows

A study published in the Proceedings of the National Academy of Sciences found that children who received cochlear implants before 30 months old fully integrated speech perception in their brains. In contrast, those who received implants later relied solely on lip movements to understand conflicting auditory and visual information.

SourceStanford Medicine·JournalProceedings of the National Academy of Sciences·DateDec 5, 2005

UCSD researchers report results of children's backpack study

The study found that pressures at 20% of body weight measured 70 mmHg on the left shoulder and 110 mmHg on the right shoulder - skin surface pressures that are more than double and triple the threshold for reduced blood flow. The researchers hope their findings will influence future backpack design to promote safety and comfort.

SourceUniversity of California - San Diego·JournalArchives of Pediatrics and Adolescent Medicine·DateDec 5, 2005

Research suggests making exercise more fun might boost fitness levels of US adolescents

A new small-scale study suggests that personal fulfillment is the strongest motivator for US adolescents to exercise. The research found that teens are more likely to participate in sports and vigorous activities if they enjoy the process and want to improve their fitness and physical skills.

SourceUniversity of North Carolina at Chapel Hill·JournalArchives of Pediatrics and Adolescent Medicine·DateDec 5, 2005